JP6728049B2 - 拡張性のある骨格筋系譜形成及び培養の方法 - Google Patents

拡張性のある骨格筋系譜形成及び培養の方法 Download PDF

Info

Publication number
JP6728049B2
JP6728049B2 JP2016552246A JP2016552246A JP6728049B2 JP 6728049 B2 JP6728049 B2 JP 6728049B2 JP 2016552246 A JP2016552246 A JP 2016552246A JP 2016552246 A JP2016552246 A JP 2016552246A JP 6728049 B2 JP6728049 B2 JP 6728049B2
Authority
JP
Japan
Prior art keywords
cell line
differentiation
cells
cell
paralogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2016552246A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016535601A5 (enExample
JP2016535601A (ja
Inventor
ジェノビーズ,ニコラス,ジェイ.
ロバーツ,アール.,マイケル
テルグー,ブハヌー,プラーカーシュ,ヴイ.,エル.
Original Assignee
ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ
ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ
メンフィス ミーツ インコーポレイテッド
メンフィス ミーツ インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53005145&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP6728049(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ, ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ, メンフィス ミーツ インコーポレイテッド, メンフィス ミーツ インコーポレイテッド filed Critical ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ
Publication of JP2016535601A publication Critical patent/JP2016535601A/ja
Publication of JP2016535601A5 publication Critical patent/JP2016535601A5/ja
Application granted granted Critical
Publication of JP6728049B2 publication Critical patent/JP6728049B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L13/00Meat products; Meat meal; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
    • C12N2501/392Sexual steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • C12N2501/415Wnt; Frizzeled
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/602Sox-2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/603Oct-3/4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/604Klf-4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • C12N2501/72Transferases [EC 2.]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • C12N2501/72Transferases [EC 2.]
    • C12N2501/727Kinases (EC 2.7.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999Small molecules not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2016552246A 2013-10-30 2014-10-30 拡張性のある骨格筋系譜形成及び培養の方法 Expired - Fee Related JP6728049B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361962068P 2013-10-30 2013-10-30
US61/962,068 2013-10-30
PCT/US2014/063250 WO2015066377A1 (en) 2013-10-30 2014-10-30 Method for scalable skeletal muscle lineage specification and cultivation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020005873A Division JP2020089381A (ja) 2013-10-30 2020-01-17 拡張性のある骨格筋系譜形成及び培養の方法

Publications (3)

Publication Number Publication Date
JP2016535601A JP2016535601A (ja) 2016-11-17
JP2016535601A5 JP2016535601A5 (enExample) 2017-12-07
JP6728049B2 true JP6728049B2 (ja) 2020-07-22

Family

ID=53005145

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016552246A Expired - Fee Related JP6728049B2 (ja) 2013-10-30 2014-10-30 拡張性のある骨格筋系譜形成及び培養の方法
JP2020005873A Pending JP2020089381A (ja) 2013-10-30 2020-01-17 拡張性のある骨格筋系譜形成及び培養の方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020005873A Pending JP2020089381A (ja) 2013-10-30 2020-01-17 拡張性のある骨格筋系譜形成及び培養の方法

Country Status (10)

Country Link
US (3) US20160251625A1 (enExample)
EP (1) EP3071040B2 (enExample)
JP (2) JP6728049B2 (enExample)
CN (2) CN111154726A (enExample)
AU (2) AU2014342180B2 (enExample)
BR (1) BR112016009803B1 (enExample)
CA (1) CA2928726A1 (enExample)
ES (1) ES2782380T5 (enExample)
IL (2) IL296889A (enExample)
WO (1) WO2015066377A1 (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016009803B1 (pt) 2013-10-30 2022-02-08 The Curators Of The University Of Missouri Método para especificação e cultivo de linhagem muscular esquelética escalonável
US11318167B2 (en) 2015-12-11 2022-05-03 The Johns Hopkins University Isolation of fusion-competent myoblasts and therapeutic applications thereof related to muscular dystrophy
CA3011484A1 (en) * 2016-01-14 2017-07-20 Memphis Meats, Inc. Methods for extending the replicative capacity of somatic cells during an ex vivo cultivation process
IL302693B2 (en) 2016-07-11 2025-10-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Methods and systems for growing cells in culture
EP4424837A3 (en) 2017-05-06 2024-12-11 Upside Foods, Inc. Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure
CA3066060A1 (en) * 2017-06-07 2018-12-13 Wild Type, Inc. Ex vivo meat production
EP3638777A4 (en) 2017-07-13 2021-05-12 Memphis Meats, Inc. COMPOSITIONS AND METHODS FOR INCREASING THE EFFICIENCY OF CELL CULTURES FOR FOOD MANUFACTURING
CA3070048A1 (en) 2017-07-15 2019-01-24 Aleph Farms Ltd. Cultured meat compositions
GB2573327B (en) * 2018-05-03 2021-05-12 Mosa Meat Bv Apparatus and process for production of tissue from cells
US12478571B2 (en) 2018-12-17 2025-11-25 Pontis Biologics, Inc. Enzyme based compositions and methods for removing dental calculi
WO2020230138A1 (en) 2019-05-14 2020-11-19 Aleph Farms Ltd. Pluripotent cell aggregates and use thereof
CN114072494B (zh) 2019-05-28 2024-01-23 阿普赛德食品公司 用于制备可食用肉制品的设备和方法
IL304043B2 (en) 2019-11-20 2024-07-01 Upside Foods Inc Apparatuses and systems for preparing a meat product
MX2022006590A (es) * 2019-12-02 2022-09-19 Avant Meats Company Ltd Metodos de produccion de carne por cultivo celular in vitro.
US20210235733A1 (en) 2020-02-04 2021-08-05 Memphis Meats, Inc. Characteristics of meat products
WO2021248141A1 (en) 2020-06-05 2021-12-09 Upside Foods, Inc. Nutrient media for the production of slaughter-free meat
GB202008821D0 (en) * 2020-06-10 2020-07-22 Highersteaks Ltd Systems and methods for cell conversion
US12252681B2 (en) 2020-08-18 2025-03-18 Upside Foods, Inc. Systems, devices, and methods for sterilizing bioreactors and culture media
US20220195368A1 (en) * 2020-12-21 2022-06-23 Upside Foods, Inc. Fluid conduit with radial expansion of fluid flow
US11912967B2 (en) 2020-12-22 2024-02-27 Upside Foods, Inc. Systems and methods for cultivating tissue on porous substrates
WO2022156939A1 (en) * 2021-01-22 2022-07-28 HigherSteaks Limited Products for cell conversion
US20240352423A1 (en) 2021-03-10 2024-10-24 Terasaki Institute For Biomedical Innovation Methods and systems of producing products such as animal derived products
AU2022254053A1 (en) 2021-04-07 2023-10-12 Upside Foods, Inc. Generation of cell-based products for consumption that comprise proteins derived from exotic, endangered, and extinct species
CN117795058A (zh) 2021-04-28 2024-03-29 阿普赛德食品公司 生产用于人类消费的基于细胞的产品
EP4334436A1 (en) 2021-05-06 2024-03-13 Yeda Research and Development Co. Ltd Method for inducing hypertrophic muscle fibers for industrial meat production
EP4346395A4 (en) * 2021-05-28 2025-04-23 ABS Global, Inc. In vitro breeding systems and methods in livestock
EP4647490A3 (en) 2021-06-11 2026-01-07 Upside Foods, Inc. Comestible cell-based meat products comprising dry cell powder and methods of making such products
AU2021450828B2 (en) 2021-06-16 2024-09-19 Upside Foods, Inc. Plant fat-based scaffolds for the growth of cell-based meats and methods of making such products
WO2023281114A1 (en) 2021-07-09 2023-01-12 Suprême Foodstuffs comprising cells differentiated from engineered oligopotent stem cells
WO2023069991A1 (en) 2021-10-19 2023-04-27 Eat Scifi Inc. Plant base/animal cell hybrid meat substitute
IL313347A (en) * 2021-12-23 2024-08-01 Upside Foods Inc Myogenic tissue augmentation: late transition myogenicity
WO2023240152A1 (en) 2022-06-07 2023-12-14 Upside Foods, Inc. Engineering cell lines capable of proliferation in growth factor free media formulations
EP4292440A1 (en) 2022-06-14 2023-12-20 Upside Foods, Inc. Suspension based chicken product formulation
EP4293109A1 (en) 2022-06-14 2023-12-20 Upside Foods, Inc. Non-skeletal muscle-derived cells as a source of suspension capable myogenic cells for cultured foods
US11981884B2 (en) 2022-10-17 2024-05-14 Upside Foods, Inc. Pipe-based bioreactors for producing comestible meat products and methods of using the same
WO2025011578A1 (zh) * 2023-07-10 2025-01-16 中国农业大学 一种猪多能干细胞的肌源性分化方法及其用于细胞培养肉制备
EP4497814A1 (de) 2023-07-28 2025-01-29 Green Elephant Biotech GmbH Vorrichtung zur vermehrung von differenzierten und undifferenzierten zellen und verwendung der vorrichtung für die herstellung von kultivierten lebensmitteln
IL325324A (en) 2023-09-01 2026-02-01 Upside Foods Inc Transposon system and methods of using it
US20250120418A1 (en) * 2023-10-12 2025-04-17 Btl Healthcare Technologies A.S. Pet food, methods and devices for producing pet food
WO2025141211A1 (en) * 2023-12-29 2025-07-03 Meatable B.V. Cells for forward programming

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510254A (en) 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
IE904639A1 (en) * 1989-12-21 1991-07-17 Univ Georgia Bovine myogenic factor gene
US5298422A (en) * 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
WO1999031222A1 (en) 1997-12-18 1999-06-24 Willem Frederik Van Eelen Industrial scale production of meat from in vitro cell cultures
WO1999043786A2 (en) 1998-02-27 1999-09-02 Purdue Research Foundation Submucosa gel compositions
US6537782B1 (en) 1998-06-01 2003-03-25 Chugai Seiyaku Kabushiki Kaisha Media for culturing animal cells and process for producing protein by using the same
US6835390B1 (en) 2000-11-17 2004-12-28 Jon Vein Method for producing tissue engineered meat for consumption
EP1639097B1 (en) * 2003-06-25 2013-08-07 Ottawa Health Research Institute Methods and compositions for modulating stem cell growth and differentiation
DE102004017484B4 (de) 2004-04-08 2006-07-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Herstellung einer biologischen Materialzusammensetzung tierischen Ursprungs
US20060121006A1 (en) 2004-09-10 2006-06-08 Chancellor Michael B Production of nutritional and therapeutic products from cultured animal cells
EP1789063B1 (en) 2004-09-17 2011-12-14 Jon Vein Tissue engineered meat for consumption and a method for producing tissue engineered meat for consumption
US8226973B2 (en) * 2005-11-02 2012-07-24 Nestec, S. A. Isoflavone compositions for reducing accumulation of body fat in male mammals, and methods for their use
KR20080108487A (ko) * 2006-02-28 2008-12-15 트르스티스 오브 보스톤 유니버시티 대사 조절인자 및 그의 용도
DE102007029699B4 (de) 2007-06-27 2010-12-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Isolierte proliferierende Zellen mit Stammzelleigenschaften aus adultem Gewebe von wechselwarmen Wirbeltieren, stabile Zellkulturen davon und Verfahren zu deren Herstellung
CN101624570B (zh) 2008-07-07 2011-04-13 刘志军 中药培养养殖肉灵芝方法及养殖肉灵芝保健品的制备方法
WO2010068897A2 (en) 2008-12-12 2010-06-17 Kedar Challakere Stem cell enhanced protein products and uses thereof
US20110091604A1 (en) 2009-10-21 2011-04-21 Seth Adrian Miller Synthetic meat
WO2012034101A2 (en) 2010-09-09 2012-03-15 The Regents Of The University Of California Expandable cell source of neuronal stem cell populations and methods for obtaining and using them
WO2012170995A2 (en) * 2011-06-10 2012-12-13 University Of Georgia Research Foundation, Inc. Avian induced pluripotent stem cells and their use
US8900572B2 (en) * 2011-06-14 2014-12-02 UNIVERSITé LAVAL Myogenic differentiation of stem cells and uses thereof
WO2012176023A1 (en) 2011-06-23 2012-12-27 Indian Institute Of Technology Kanpur Hydrogel scaffolds for tissue engineering
KR102724112B1 (ko) 2011-07-12 2024-10-31 임파서블 푸즈 인크. 소비재를 위한 방법 및 조성물
US10039306B2 (en) 2012-03-16 2018-08-07 Impossible Foods Inc. Methods and compositions for consumables
JP6523683B2 (ja) 2011-07-26 2019-06-05 ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ 加工食用肉
CA2792081C (en) * 2011-10-11 2020-10-27 Bond University Ltd Layered compositions comprising 3d nanofibre webbing for tissue repair
WO2013073246A1 (en) * 2011-11-18 2013-05-23 Kyoto University Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
US9737875B2 (en) 2012-03-16 2017-08-22 Impossible Foods Inc. Affinity reagents for protein purification
CN104603293A (zh) 2012-03-28 2015-05-06 现代牧场有限公司 工程的皮革和其制造方法
BR112015016651A2 (pt) 2013-01-11 2017-07-11 Impossible Foods Inc réplica de queijo não láctea compreendendo um coacervado
PT2959005T (pt) 2013-02-22 2021-12-30 Univ Leland Stanford Junior Utilização médica relacionada com extensão de telómero
WO2015038988A1 (en) 2013-09-13 2015-03-19 Modern Meadow, Inc. Edible and animal-product-free microcarriers for engineered meat
BR112016009803B1 (pt) 2013-10-30 2022-02-08 The Curators Of The University Of Missouri Método para especificação e cultivo de linhagem muscular esquelética escalonável
US20150296834A1 (en) 2014-04-17 2015-10-22 Savage River, Inc. dba Beyond Meat, Inc. Plant based meat structured protein products
US9526267B2 (en) 2014-04-17 2016-12-27 Savage River, Inc. Nutrient-dense meat structured protein products
WO2017019125A1 (en) 2015-07-24 2017-02-02 Synthetic Genomics, Inc. A protein rich food ingredient from biomass and methods of production
CA3011484A1 (en) 2016-01-14 2017-07-20 Memphis Meats, Inc. Methods for extending the replicative capacity of somatic cells during an ex vivo cultivation process
EP4424837A3 (en) 2017-05-06 2024-12-11 Upside Foods, Inc. Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure
EP3638777A4 (en) 2017-07-13 2021-05-12 Memphis Meats, Inc. COMPOSITIONS AND METHODS FOR INCREASING THE EFFICIENCY OF CELL CULTURES FOR FOOD MANUFACTURING

Also Published As

Publication number Publication date
AU2019202244B2 (en) 2021-09-23
AU2019202244A1 (en) 2019-04-18
IL296889A (en) 2022-12-01
US20160251625A1 (en) 2016-09-01
BR112016009803B1 (pt) 2022-02-08
WO2015066377A1 (en) 2015-05-07
BR112016009803A2 (pt) 2017-12-05
IL245292A0 (en) 2016-06-30
ES2782380T3 (es) 2020-09-14
US20160227830A1 (en) 2016-08-11
CN105899079A (zh) 2016-08-24
JP2016535601A (ja) 2016-11-17
AU2014342180B2 (en) 2019-01-03
CN111154726A (zh) 2020-05-15
AU2014342180A1 (en) 2016-05-19
JP2020089381A (ja) 2020-06-11
CA2928726A1 (en) 2015-05-07
IL245292B (en) 2022-10-01
EP3071040A1 (en) 2016-09-28
BR112016009803A8 (pt) 2018-01-30
IL245292B2 (en) 2023-02-01
US10920196B2 (en) 2021-02-16
EP3071040B2 (en) 2022-12-28
ES2782380T5 (es) 2023-05-08
EP3071040B1 (en) 2020-01-01
EP3071040A4 (en) 2017-06-21
US20210171912A1 (en) 2021-06-10

Similar Documents

Publication Publication Date Title
JP2020089381A (ja) 拡張性のある骨格筋系譜形成及び培養の方法
US9670463B2 (en) Inhibition and enhancement of reprogramming by chromatin modifying enzymes
US20120034192A1 (en) Compositions and methods for enhancing cell reprogramming
CN121175408A (zh) 骨骼肌细胞的成熟
Mo et al. Generation and characterization of bat-induced pluripotent stem cells
KR20140101390A (ko) 반수체 세포
WO2014069479A1 (ja) 分化多能性幹細胞の製造方法
CA3221942A1 (en) Foodstuffs comprising cells differentiated from engineered oligopotent stem cells
JP6351018B2 (ja) アミノ酸組成変更培地を用いた幹細胞の分化誘導方法、及び該培地を含む培地キット
CA3201825A1 (en) Compositions and methods for gene editing with woolly mammoth alleles
JP2015536143A (ja) 細胞分化
Sandoval et al. Tumor suppressors inhibit reprogramming of African spiny mouse (Acomys) fibroblasts to induced pluripotent stem cells
WO2023067090A1 (en) Ipsc induction and progeny derivation
JPWO2017073763A1 (ja) 多能性幹細胞の分化抵抗性を減弱する方法
HK1229164A1 (en) Method for scalable skeletal muscle lineage specification and cultivation
HK1229164B (en) Method for scalable skeletal muscle lineage specification and cultivation
Aimaletdinov et al. Isolation and Cultivation of Sterlet Myoblasts
Heffernan et al. Induction of pluripotency
Morey Ramonell et al. Pluripotency and epigenetic factors in mouse embryonic stem cell fate regulation
Autio Investigating the Regulation of Distinct Epigenetic States in Human Embryonic Stem Cells
정현교 Studies on Transcriptional and Epigenetic Mechanisms of NANOG gene in Chicken Primordial Germ Cells
Page et al. Methods for Inducing Pluripotency

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171030

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20171030

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20181002

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20181217

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190402

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20190917

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200117

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200305

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20200325

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20200602

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20200701

R150 Certificate of patent or registration of utility model

Ref document number: 6728049

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees