JP6727237B2 - 血液がん及び固形腫瘍の治療のための併用療法 - Google Patents

血液がん及び固形腫瘍の治療のための併用療法 Download PDF

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JP6727237B2
JP6727237B2 JP2017568243A JP2017568243A JP6727237B2 JP 6727237 B2 JP6727237 B2 JP 6727237B2 JP 2017568243 A JP2017568243 A JP 2017568243A JP 2017568243 A JP2017568243 A JP 2017568243A JP 6727237 B2 JP6727237 B2 JP 6727237B2
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JP2018524347A5 (enExample
JP2018524347A (ja
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ガンディー アニタ
ガンディー アニタ
チウ フシリング
チウ フシリング
ポウルデフナド マイケル
ポウルデフナド マイケル
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
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  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017568243A 2015-07-02 2016-07-01 血液がん及び固形腫瘍の治療のための併用療法 Expired - Fee Related JP6727237B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562188404P 2015-07-02 2015-07-02
US62/188,404 2015-07-02
US201562245916P 2015-10-23 2015-10-23
US62/245,916 2015-10-23
US201662308055P 2016-03-14 2016-03-14
US62/308,055 2016-03-14
US201662340972P 2016-05-24 2016-05-24
US62/340,972 2016-05-24
PCT/US2016/040718 WO2017004532A1 (en) 2015-07-02 2016-07-01 Combination therapy for treatment of hematological cancers and solid tumors

Related Child Applications (1)

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JP2020112519A Division JP2020172502A (ja) 2015-07-02 2020-06-30 血液がん及び固形腫瘍の治療のための併用療法

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JP2018524347A JP2018524347A (ja) 2018-08-30
JP2018524347A5 JP2018524347A5 (enExample) 2019-08-15
JP6727237B2 true JP6727237B2 (ja) 2020-07-22

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JP2020112519A Pending JP2020172502A (ja) 2015-07-02 2020-06-30 血液がん及び固形腫瘍の治療のための併用療法

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US (1) US10973822B2 (enExample)
EP (1) EP3316888A1 (enExample)
JP (2) JP6727237B2 (enExample)
KR (1) KR20180023968A (enExample)
AU (1) AU2016288246A1 (enExample)
BR (1) BR112017028530A2 (enExample)
CA (1) CA2991164A1 (enExample)
EA (1) EA201890199A1 (enExample)
MX (1) MX2018000216A (enExample)
WO (1) WO2017004532A1 (enExample)

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MX2018000216A (es) 2018-05-22
WO2017004532A1 (en) 2017-01-05
CA2991164A1 (en) 2017-01-05
EA201890199A1 (ru) 2018-06-29
EP3316888A1 (en) 2018-05-09
AU2016288246A1 (en) 2018-02-01
JP2018524347A (ja) 2018-08-30
BR112017028530A2 (pt) 2018-08-28
US10973822B2 (en) 2021-04-13
KR20180023968A (ko) 2018-03-07
US20180193342A1 (en) 2018-07-12
JP2020172502A (ja) 2020-10-22

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