JP6694827B2 - Ｍｄｍ２阻害剤及びそれを使用する治療方法 - Google Patents
Ｍｄｍ２阻害剤及びそれを使用する治療方法 Download PDFInfo
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
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Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020033622A JP6909323B2 (ja) | 2014-04-17 | 2020-02-28 | Ｍｄｍ２阻害剤及びそれを使用する治療方法 |
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| US201461980747P | 2014-04-17 | 2014-04-17 | |
| US61/980,747 | 2014-04-17 | ||
| PCT/US2015/026098 WO2015161032A1 (en) | 2014-04-17 | 2015-04-16 | Mdm2 inhibitors and therapeutic methods using the same |
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| JP2020033622A Division JP6909323B2 (ja) | 2014-04-17 | 2020-02-28 | Ｍｄｍ２阻害剤及びそれを使用する治療方法 |
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| JP2017511360A JP2017511360A (ja) | 2017-04-20 |
| JP2017511360A5 JP2017511360A5 (OSRAM) | 2018-05-17 |
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| JP2020033622A Active JP6909323B2 (ja) | 2014-04-17 | 2020-02-28 | Ｍｄｍ２阻害剤及びそれを使用する治療方法 |
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| JP2020033622A Active JP6909323B2 (ja) | 2014-04-17 | 2020-02-28 | Ｍｄｍ２阻害剤及びそれを使用する治療方法 |
Country Status (12)
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| US (1) | US9745314B2 (OSRAM) |
| EP (1) | EP3131544B1 (OSRAM) |
| JP (2) | JP6694827B2 (OSRAM) |
| KR (2) | KR102599945B1 (OSRAM) |
| CN (2) | CN111718354A (OSRAM) |
| AU (1) | AU2015247646B2 (OSRAM) |
| CA (1) | CA2945527C (OSRAM) |
| ES (1) | ES2712973T3 (OSRAM) |
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| JP2020100662A (ja) * | 2014-04-17 | 2020-07-02 | ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン | Ｍｄｍ２阻害剤及びそれを使用する治療方法 |
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