JP6685925B2 - 治療用として改善された特性を有するβ−ラクタマーゼ - Google Patents
治療用として改善された特性を有するβ−ラクタマーゼ Download PDFInfo
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- JP6685925B2 JP6685925B2 JP2016562248A JP2016562248A JP6685925B2 JP 6685925 B2 JP6685925 B2 JP 6685925B2 JP 2016562248 A JP2016562248 A JP 2016562248A JP 2016562248 A JP2016562248 A JP 2016562248A JP 6685925 B2 JP6685925 B2 JP 6685925B2
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- lactamase
- antibiotic
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- protein
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461980844P | 2014-04-17 | 2014-04-17 | |
| US61/980,844 | 2014-04-17 | ||
| US201462046627P | 2014-09-05 | 2014-09-05 | |
| US62/046,627 | 2014-09-05 | ||
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| WO2016144856A1 (en) * | 2015-03-06 | 2016-09-15 | Synthetic Biologics, Inc. | Safe and effective beta-lactamase dosing for microbiome protection |
| WO2017144495A1 (en) * | 2016-02-23 | 2017-08-31 | Da Volterra | Beta-lactamase variants |
| US10982205B2 (en) | 2016-02-23 | 2021-04-20 | Da Volterra | Beta-lactamase variants |
| WO2018005606A1 (en) | 2016-06-28 | 2018-01-04 | Synthetic Biologics, Inc. | Microbiome protection from oral antibiotics |
| KR20210040395A (ko) | 2018-08-05 | 2021-04-13 | 다 볼떼라 | 이식편 대 숙주 질환의 치료를 위한 조성물 |
| AU2019317986A1 (en) | 2018-08-05 | 2021-02-11 | Da Volterra | Method for improving anticancer agent efficacy |
| CN109337889B (zh) * | 2018-12-26 | 2020-10-02 | 广州白云山拜迪生物医药有限公司 | 一种酶活提高的金属β-内酰胺酶突变体及其构建方法 |
| CN109576250A (zh) * | 2018-12-26 | 2019-04-05 | 广州白云山拜迪生物医药有限公司 | 一种酶活提高的头孢菌素酶突变体及其构建方法 |
| CN113939308A (zh) * | 2019-05-06 | 2022-01-14 | 合成生物制品有限公司 | 用于治疗移植物抗宿主病的β-内酰胺酶组合物 |
| EP4148136A1 (en) | 2021-09-08 | 2023-03-15 | Da Volterra | An engineered yeast cell for the delivery of antibiotic-inactivating enzymes |
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