JP6675981B2 - 内視鏡的粘膜切除術および/または内視鏡的粘膜下層剥離術に使用するためのエマルジョンまたはマイクロエマルジョン - Google Patents

内視鏡的粘膜切除術および/または内視鏡的粘膜下層剥離術に使用するためのエマルジョンまたはマイクロエマルジョン Download PDF

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JP6675981B2
JP6675981B2 JP2016533027A JP2016533027A JP6675981B2 JP 6675981 B2 JP6675981 B2 JP 6675981B2 JP 2016533027 A JP2016533027 A JP 2016533027A JP 2016533027 A JP2016533027 A JP 2016533027A JP 6675981 B2 JP6675981 B2 JP 6675981B2
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pharmaceutical composition
emulsion
oil
microemulsion
microemulsion according
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JP2016540754A5 (de
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マリア ロンゴ ルイージ
マリア ロンゴ ルイージ
モーロ ルイージ
モーロ ルイージ
フリモンティ エンリコ
フリモンティ エンリコ
レピシ アレッサンドロ
レピシ アレッサンドロ
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コスモ・テクノロジーズ・リミテツド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/006Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0005Ingredients of undetermined constitution or reaction products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/442Colorants, dyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions

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  • Health & Medical Sciences (AREA)
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  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Oncology (AREA)
  • Optics & Photonics (AREA)
  • Materials Engineering (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Polymers & Plastics (AREA)
  • Surgical Instruments (AREA)
  • Endoscopes (AREA)
  • Cosmetics (AREA)
JP2016533027A 2013-11-20 2014-11-18 内視鏡的粘膜切除術および/または内視鏡的粘膜下層剥離術に使用するためのエマルジョンまたはマイクロエマルジョン Active JP6675981B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2020041957A JP6978537B2 (ja) 2013-11-20 2020-03-11 内視鏡的粘膜切除術および/または内視鏡的粘膜下層剥離術に使用するためのエマルジョンまたはマイクロエマルジョン

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT001924A ITMI20131924A1 (it) 2013-11-20 2013-11-20 Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica
ITMI2013A001924 2013-11-20
PCT/EP2014/074886 WO2015075024A1 (en) 2013-11-20 2014-11-18 Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection.

Related Child Applications (1)

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JP2020041957A Division JP6978537B2 (ja) 2013-11-20 2020-03-11 内視鏡的粘膜切除術および/または内視鏡的粘膜下層剥離術に使用するためのエマルジョンまたはマイクロエマルジョン

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JP2016540754A JP2016540754A (ja) 2016-12-28
JP2016540754A5 JP2016540754A5 (de) 2017-12-28
JP6675981B2 true JP6675981B2 (ja) 2020-04-08

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JP2020041957A Active JP6978537B2 (ja) 2013-11-20 2020-03-11 内視鏡的粘膜切除術および/または内視鏡的粘膜下層剥離術に使用するためのエマルジョンまたはマイクロエマルジョン

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US (7) US9987366B2 (de)
EP (2) EP2911707B1 (de)
JP (2) JP6675981B2 (de)
KR (1) KR102398802B1 (de)
CN (2) CN105848689B (de)
AU (1) AU2014352009B2 (de)
BR (1) BR112016011345B1 (de)
CA (1) CA2929911C (de)
DK (2) DK3106182T3 (de)
ES (2) ES2843521T3 (de)
HK (1) HK1210972A1 (de)
HR (2) HRP20161376T1 (de)
HU (2) HUE052870T2 (de)
IL (1) IL245118B (de)
IT (1) ITMI20131924A1 (de)
LT (2) LT3106182T (de)
MX (2) MX2016006581A (de)
NZ (1) NZ720148A (de)
PL (2) PL2911707T3 (de)
PT (2) PT3106182T (de)
RS (2) RS61290B1 (de)
RU (1) RU2696263C1 (de)
WO (1) WO2015075024A1 (de)
ZA (1) ZA201603313B (de)

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KR102027311B1 (ko) * 2019-03-27 2019-10-02 주식회사 티젤바이오 염증성 비정상 조직 또는 종양 조직의 선택적 염색이 가능한 나노 진단 제제의 제조 방법
RU203313U1 (ru) * 2020-11-18 2021-03-31 Александр Александрович Соколов Устройство для проведения холодовой ишемии при резекции
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US20180236087A1 (en) 2018-08-23
MX2016006581A (es) 2017-01-12
BR112016011345B1 (pt) 2021-01-05
IL245118B (en) 2020-04-30
CN110665047B (zh) 2022-03-18
KR20160098243A (ko) 2016-08-18
HUE031801T2 (en) 2017-08-28
US9962445B2 (en) 2018-05-08
ES2843521T3 (es) 2021-07-19
US20150141526A1 (en) 2015-05-21
LT2911707T (lt) 2016-11-10
RS55330B1 (sr) 2017-03-31
US20160296659A1 (en) 2016-10-13
US9364580B2 (en) 2016-06-14
HK1210972A1 (zh) 2016-05-13
US9522216B2 (en) 2016-12-20
HRP20161376T1 (hr) 2016-12-02
JP2020114829A (ja) 2020-07-30
NZ720148A (en) 2020-06-26
CA2929911A1 (en) 2015-05-28
PL3106182T3 (pl) 2021-05-04
US20160074554A1 (en) 2016-03-17
CA2929911C (en) 2021-11-23
EP2911707B1 (de) 2016-09-07
CN105848689B (zh) 2019-11-01
RU2016124105A (ru) 2017-12-22
CN105848689A (zh) 2016-08-10
HRP20210048T1 (hr) 2021-04-30
AU2014352009A1 (en) 2016-06-02
KR102398802B1 (ko) 2022-05-18
JP6978537B2 (ja) 2021-12-08
EP3106182A1 (de) 2016-12-21
CN110665047A (zh) 2020-01-10
LT3106182T (lt) 2021-04-26
ITMI20131924A1 (it) 2015-05-21
IL245118A0 (en) 2016-06-30
US10413611B2 (en) 2019-09-17
WO2015075024A1 (en) 2015-05-28
AU2014352009B2 (en) 2017-09-07
EP3106182B1 (de) 2020-10-21
US9226996B2 (en) 2016-01-05
ES2602964T3 (es) 2017-02-23
EP2911707A1 (de) 2015-09-02
US10849979B2 (en) 2020-12-01
MX2020011901A (es) 2022-05-13
RU2696263C1 (ru) 2019-08-01
US20160256594A1 (en) 2016-09-08
DK3106182T3 (da) 2021-01-18
US20200000926A1 (en) 2020-01-02
PL2911707T3 (pl) 2017-02-28
JP2016540754A (ja) 2016-12-28
US9987366B2 (en) 2018-06-05
ZA201603313B (en) 2017-09-27
PT2911707T (pt) 2016-11-28
PT3106182T (pt) 2021-01-18
US20170043018A1 (en) 2017-02-16
RS61290B1 (sr) 2021-02-26
DK2911707T3 (en) 2016-12-05

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