JP6643996B2 - アンジオポエチン様３発現の調節 - Google Patents

アンジオポエチン様３発現の調節 Download PDF

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JP6643996B2
JP6643996B2 JP2016542739A JP2016542739A JP6643996B2 JP 6643996 B2 JP6643996 B2 JP 6643996B2 JP 2016542739 A JP2016542739 A JP 2016542739A JP 2016542739 A JP2016542739 A JP 2016542739A JP 6643996 B2 JP6643996 B2 JP 6643996B2
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certain embodiments
antisense
modified
compound
angptl3
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JP2017505116A (ja
JP2017505116A5 (https=
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フレアー，スーザン・エム
グラハム，マーク・ジェイ
クルック，ロザンヌ・エム
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Ionis Pharmaceuticals Inc
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Ionis Pharmaceuticals Inc
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2016542739A 2013-12-24 2014-12-24 アンジオポエチン様３発現の調節 Expired - Fee Related JP6643996B2 (ja)

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US201361920652P 2013-12-24 2013-12-24
US61/920,652 2013-12-24
PCT/US2014/072303 WO2015100394A1 (en) 2013-12-24 2014-12-24 Modulation of angiopoietin-like 3 expression

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JP2020000628A Division JP2020072713A (ja) 2013-12-24 2020-01-07 アンジオポエチン様３発現の調節

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JP2017505116A JP2017505116A (ja) 2017-02-16
JP2017505116A5 JP2017505116A5 (https=) 2018-02-08
JP6643996B2 true JP6643996B2 (ja) 2020-02-12

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US (3) US20170037409A1 (https=)
EP (2) EP3087183B1 (https=)
JP (2) JP6643996B2 (https=)
KR (2) KR102298476B1 (https=)
CN (3) CN111394355A (https=)
AU (2) AU2014369900B2 (https=)
BR (1) BR112016013473A2 (https=)
CA (1) CA2931510A1 (https=)
DK (1) DK3087183T3 (https=)
ES (1) ES2830257T3 (https=)
HU (1) HUE052243T2 (https=)
IL (2) IL245707B (https=)
MX (1) MX383753B (https=)
NZ (1) NZ720286A (https=)
PL (1) PL3087183T3 (https=)
PT (1) PT3087183T (https=)
RU (1) RU2706964C2 (https=)
SI (1) SI3087183T1 (https=)
WO (1) WO2015100394A1 (https=)

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CN110944675B9 (zh) 2017-12-01 2024-08-09 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
AU2018394875B2 (en) 2017-12-29 2023-08-03 Suzhou Ribo Life Science Co., Ltd. Conjugates and preparation and use thereof
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KR20220011689A (ko) 2019-05-22 2022-01-28 쑤저우 리보 라이프 사이언스 컴퍼니, 리미티드 핵산, 약제학적 조성물, 접합체, 제조 방법, 및 용도
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