JP6607855B2 - 薬物送達デバイスのアセンブリ - Google Patents

薬物送達デバイスのアセンブリ Download PDF

Info

Publication number
JP6607855B2
JP6607855B2 JP2016531071A JP2016531071A JP6607855B2 JP 6607855 B2 JP6607855 B2 JP 6607855B2 JP 2016531071 A JP2016531071 A JP 2016531071A JP 2016531071 A JP2016531071 A JP 2016531071A JP 6607855 B2 JP6607855 B2 JP 6607855B2
Authority
JP
Japan
Prior art keywords
piston rod
assembly
guide
lead screw
housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016531071A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016537105A (ja
JP2016537105A5 (enExample
Inventor
シュテファン・ブランク
アクセル・トイチャー
ミヒャエル・ユーグル
クリスティアン・シュナイダー
Original Assignee
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング filed Critical サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
Publication of JP2016537105A publication Critical patent/JP2016537105A/ja
Publication of JP2016537105A5 publication Critical patent/JP2016537105A5/ja
Application granted granted Critical
Publication of JP6607855B2 publication Critical patent/JP6607855B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2016531071A 2013-11-22 2014-11-17 薬物送達デバイスのアセンブリ Active JP6607855B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361907724P 2013-11-22 2013-11-22
US61/907,724 2013-11-22
EP14165751 2014-04-24
EP14165751.0 2014-04-24
PCT/EP2014/074708 WO2015074982A1 (en) 2013-11-22 2014-11-17 Assembly for a drug delivery device

Publications (3)

Publication Number Publication Date
JP2016537105A JP2016537105A (ja) 2016-12-01
JP2016537105A5 JP2016537105A5 (enExample) 2019-09-12
JP6607855B2 true JP6607855B2 (ja) 2019-11-20

Family

ID=50542896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016531071A Active JP6607855B2 (ja) 2013-11-22 2014-11-17 薬物送達デバイスのアセンブリ

Country Status (6)

Country Link
US (2) US10537684B2 (enExample)
EP (1) EP3071268B1 (enExample)
JP (1) JP6607855B2 (enExample)
CN (1) CN105744976B (enExample)
DK (1) DK3071268T3 (enExample)
WO (1) WO2015074982A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6479795B2 (ja) * 2013-11-22 2019-03-06 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス
US10617825B2 (en) * 2014-06-27 2020-04-14 Sanofi-Aventis Deutschland Gmbh Drug delivery device
EP3170527B1 (en) * 2015-11-23 2023-04-12 SHL Medical AG Medicament delivery device
US11135376B2 (en) * 2016-03-15 2021-10-05 Sanofi Dosing mechanism for multi-shot injection device comprising flexible ratchet element
CN206837199U (zh) * 2016-12-05 2018-01-05 甘肃成纪生物药业有限公司 一种药物输送装置及其防退机构
US10327854B2 (en) * 2017-02-02 2019-06-25 Ethicon Llc Robotic surgical system and methods for articulation calibration
US10934088B2 (en) * 2018-01-18 2021-03-02 Srm, Llc Manway open and close assist device
US11839748B2 (en) 2018-09-07 2023-12-12 Cc Biotechnology Corporation Plunging apparatus for syringe
CN109512235B (zh) * 2019-01-14 2023-05-09 北京小米移动软件有限公司 可穿戴设备、食物补给方法、装置及存储介质
WO2022013155A1 (en) 2020-07-15 2022-01-20 Novo Nordisk A/S A reusable torsion spring driven injection device
CN115887821B (zh) * 2022-11-01 2024-09-27 江苏欧凯医疗器械科技有限公司 可重复使用的注射笔

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US533575A (en) 1895-02-05 wilkens
GB8713810D0 (en) * 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
US5226895A (en) 1989-06-05 1993-07-13 Eli Lilly And Company Multiple dose injection pen
GB9007113D0 (en) 1990-03-29 1990-05-30 Sams Bernard Dispensing device
EP0498737B1 (en) * 1991-02-07 1995-07-19 Terumo Kabushiki Kaisha Dosing means for an injector
JPH04256758A (ja) 1991-02-07 1992-09-11 Terumo Corp 定量分与器
JPH05103833A (ja) * 1991-04-18 1993-04-27 Terumo Corp 薬剤定量分与器
DE59202070D1 (de) 1991-07-24 1995-06-08 Medico Dev Investment Co Injektor.
DK175491D0 (da) 1991-10-18 1991-10-18 Novo Nordisk As Apparat
US5279586A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Reusable medication delivery pen
US5320609A (en) 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
US5383865A (en) 1993-03-15 1995-01-24 Eli Lilly And Company Medication dispensing device
ZA941881B (en) 1993-04-02 1995-09-18 Lilly Co Eli Manifold medication injection apparatus and method
US5582598A (en) 1994-09-19 1996-12-10 Becton Dickinson And Company Medication delivery pen with variable increment dose scale
AU696439B2 (en) 1995-03-07 1998-09-10 Eli Lilly And Company Recyclable medication dispensing device
AU1860697A (en) * 1995-09-08 1997-07-28 Visionary Medical Products Corporation Pen-type injector drive mechanism
US5674204A (en) 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
US5688251A (en) 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
DE19730999C1 (de) 1997-07-18 1998-12-10 Disetronic Licensing Ag Dosierknopfsicherung an einer Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
US5957896A (en) 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
UA56256C2 (uk) 1998-01-30 2003-05-15 Ново Нордіск А/С Шприц для ін'єкцій
US5961495A (en) 1998-02-20 1999-10-05 Becton, Dickinson And Company Medication delivery pen having a priming mechanism
US6221053B1 (en) 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
US6248095B1 (en) 1998-02-23 2001-06-19 Becton, Dickinson And Company Low-cost medication delivery pen
US6936032B1 (en) 1999-08-05 2005-08-30 Becton, Dickinson And Company Medication delivery pen
GB0007071D0 (en) 2000-03-24 2000-05-17 Sams Bernard One-way clutch mechanisms and injector devices
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
US6899699B2 (en) 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
EP2275158B1 (en) 2001-05-16 2013-01-23 Eli Lilly and Company Medication injector apparatus
JP4288156B2 (ja) 2001-07-16 2009-07-01 イーライ リリー アンド カンパニー 充填用に回転かつ注射用にプル・プッシュ形式の投薬装置
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
KR101121317B1 (ko) * 2003-08-12 2012-03-09 일라이 릴리 앤드 캄파니 기계적 확대율을 갖는 삼중 나사식 쓰레드를 갖는 약제투여 장치
DE102004063648A1 (de) 2004-12-31 2006-07-20 Tecpharma Licensing Ag Injektions- oder Infusionsgerät mit Lebensdauer-Ermittlungseinrichtung
CN101600468B (zh) 2006-12-21 2012-12-12 诺沃-诺迪斯克有限公司 注射器装置
US8647309B2 (en) 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
AR086257A1 (es) * 2011-05-06 2013-11-27 Sanofi Aventis Deutschland Dispositivo de administracion de farmacos y soporte de cartucho para un dispositivo de administracion de farmacos
PL220720B1 (pl) * 2012-02-08 2015-12-31 Copernicus Spółka Z Ograniczoną Odpowiedzialnością Urządzenie wstrzykujące z mechanizmem resetu dawki
JP6535666B2 (ja) * 2013-11-22 2019-06-26 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 用量終了フィードバック（ｅｎｄ ｏｆ ｄｏｓｅ ｆｅｅｄｂａｃｋ）を有する薬物送達デバイス
CN105764555A (zh) * 2013-11-22 2016-07-13 赛诺菲-安万特德国有限公司 具有剂量输送咔哒发声器的药物输送装置
HK1225664A1 (zh) * 2013-12-20 2017-09-15 Sanofi-Aventis Deutschland Gmbh 用於药物输送装置的组件和药物输送装置
EP2891503A1 (en) * 2014-01-02 2015-07-08 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device
EP3061478A1 (en) * 2015-02-27 2016-08-31 Sanofi-Aventis Deutschland GmbH Medicament delivery device and method for assembling same

Also Published As

Publication number Publication date
US11065389B2 (en) 2021-07-20
EP3071268A1 (en) 2016-09-28
CN105744976B (zh) 2019-11-29
US20160287799A1 (en) 2016-10-06
EP3071268B1 (en) 2019-04-03
US20190224420A1 (en) 2019-07-25
CN105744976A (zh) 2016-07-06
JP2016537105A (ja) 2016-12-01
US10537684B2 (en) 2020-01-21
DK3071268T3 (da) 2019-06-24
WO2015074982A1 (en) 2015-05-28

Similar Documents

Publication Publication Date Title
JP6607855B2 (ja) 薬物送達デバイスのアセンブリ
JP6711749B2 (ja) 用量ノブクラッチ（ｄｏｓｅ ｋｎｏｂ ｃｌｕｔｃｈ）を有する薬物送達デバイス
JP6518246B2 (ja) ばね支援薬物送達デバイス
JP6535666B2 (ja) 用量終了フィードバック（ｅｎｄ ｏｆ ｄｏｓｅ ｆｅｅｄｂａｃｋ）を有する薬物送達デバイス
JP6473750B2 (ja) 用量送達クリッカを有する薬物送達デバイス
JP6618902B2 (ja) ばね支援薬物送達デバイス
US20160287802A1 (en) Drug delivery device with dose delivery clicker
JP6815198B2 (ja) 一方向カップリングを有する薬物送達デバイス
JP6479795B2 (ja) 薬物送達デバイス
JP6566946B2 (ja) 偽造防止機能を有する薬物送達デバイス
HK1225669B (en) Assembly for a drug delivery device
HK1225669A1 (en) Assembly for a drug delivery device
HK1225667B (en) Drug delivery device with unidirectional coupling
HK1225667A1 (en) Drug delivery device with unidirectional coupling
HK1225668B (en) Drug delivery device
HK1225668A1 (en) Drug delivery device
HK1225663A1 (en) Spring assisted drug delivery device
HK1225663B (en) Spring assisted drug delivery device

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171106

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20171106

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180904

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180831

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181128

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190507

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20190805

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20190924

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20191021

R150 Certificate of patent or registration of utility model

Ref document number: 6607855

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250