JP6589086B2 - 抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法 - Google Patents

抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法 Download PDF

Info

Publication number
JP6589086B2
JP6589086B2 JP2016507106A JP2016507106A JP6589086B2 JP 6589086 B2 JP6589086 B2 JP 6589086B2 JP 2016507106 A JP2016507106 A JP 2016507106A JP 2016507106 A JP2016507106 A JP 2016507106A JP 6589086 B2 JP6589086 B2 JP 6589086B2
Authority
JP
Japan
Prior art keywords
composition
fatty acid
antifungal
group
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2016507106A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016516765A (ja
JP2016516765A5 (enExample
Inventor
スダナンド プラサッド
スダナンド プラサッド
スマナ ゴーシュ
スマナ ゴーシュ
スレッシュ ラメシュラル チャウライ
スレッシュ ラメシュラル チャウライ
ニル ジャイン
ニル ジャイン
Original Assignee
ビョーメ セラピューティクス リミテッド
ビョーメ セラピューティクス リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ビョーメ セラピューティクス リミテッド, ビョーメ セラピューティクス リミテッド filed Critical ビョーメ セラピューティクス リミテッド
Publication of JP2016516765A publication Critical patent/JP2016516765A/ja
Publication of JP2016516765A5 publication Critical patent/JP2016516765A5/ja
Application granted granted Critical
Publication of JP6589086B2 publication Critical patent/JP6589086B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/06—Preparations for styling the hair, e.g. by temporary shaping or colouring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00—Manicure or pedicure preparations
    • A61Q3/02—Nail coatings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2016507106A 2013-04-12 2014-04-12 抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法 Expired - Fee Related JP6589086B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1103DE2013 2013-04-12
IN1103/DEL/2013 2013-04-12
PCT/IB2014/060675 WO2014167554A2 (en) 2013-04-12 2014-04-12 Composition and formulation of antimicrobial agents, processes thereof and methods for treating microbial infections

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018206681A Division JP2019031561A (ja) 2013-04-12 2018-11-01 抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法

Publications (3)

Publication Number Publication Date
JP2016516765A JP2016516765A (ja) 2016-06-09
JP2016516765A5 JP2016516765A5 (enExample) 2018-03-15
JP6589086B2 true JP6589086B2 (ja) 2019-10-16

Family

ID=50685993

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016507106A Expired - Fee Related JP6589086B2 (ja) 2013-04-12 2014-04-12 抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法
JP2018206681A Pending JP2019031561A (ja) 2013-04-12 2018-11-01 抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018206681A Pending JP2019031561A (ja) 2013-04-12 2018-11-01 抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法

Country Status (9)

Country Link
US (1) US20160058775A1 (enExample)
EP (1) EP2983714A2 (enExample)
JP (2) JP6589086B2 (enExample)
KR (1) KR101862448B1 (enExample)
CN (1) CN105263525A (enExample)
AU (1) AU2014252157B2 (enExample)
EA (1) EA201591954A1 (enExample)
HK (1) HK1220624A1 (enExample)
WO (1) WO2014167554A2 (enExample)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2793833B1 (en) * 2011-12-20 2020-06-24 Vyome Therapeutics Limited Topical oil composition for the treatment of fungal infections
CN113559105B (zh) * 2014-01-29 2026-06-23 维奥姆治疗有限公司 抗性痤疮的治疗
MX388267B (es) 2014-11-19 2025-03-19 Univ Kansas State Mitigantes quimicos en alimento para animales e ingredientes alimentarios.
WO2016118644A1 (en) 2015-01-20 2016-07-28 Plurogen Therapeutics, Llc Compositions and methods of treating microbes
US11446236B2 (en) 2015-08-05 2022-09-20 Cmpd Licensing, Llc Topical antimicrobial compositions and methods of formulating the same
US10898455B2 (en) 2016-01-07 2021-01-26 Cmpd Licensing, Llc Urea cream formulations
US11684567B2 (en) 2015-08-05 2023-06-27 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11690815B2 (en) 2015-08-05 2023-07-04 Cmpd Licensing Llc Hyperkeratotic skin condition treatments and compositions
US11793783B2 (en) 2015-08-05 2023-10-24 Cmpd Licensing, Llc Compositions and methods for treating an infection
US20170173063A1 (en) * 2015-12-18 2017-06-22 Cmpd Licensing, Llc Compositions and Methods for Treating an Infection
CN109512998A (zh) * 2016-03-04 2019-03-26 广州英赛特生物技术有限公司 含氧碳氢衍生物的酯化衍生物作为多粘菌素的协同增效剂的应用
JP6085706B1 (ja) * 2016-03-31 2017-02-22 株式会社ポーラファルマ 抗トリトリコモナス剤
WO2017216722A2 (en) * 2016-06-13 2017-12-21 Vyome Biosciences Pvt. Ltd. Synergistic antifungal compositions and methods thereof
KR20190037229A (ko) * 2016-06-13 2019-04-05 바이옴 테라퓨틱스 리미티드 상승효과적 항진균 조성물 및 그의 방법
GB201611365D0 (en) * 2016-06-30 2016-08-17 Devenish Nutrition Ltd A composition for use in treating rotavirus infection
CN106178024A (zh) * 2016-07-06 2016-12-07 安徽智博新材料科技有限公司 一种医用器具的长效消毒方法
EA201991712A1 (ru) * 2017-01-19 2020-01-14 Др. Редди'З Лабораториз Лимитед Композиции бесконсервантных шампуней
EA201992520A1 (ru) * 2017-07-12 2020-06-25 Юнилевер Н.В. Масло, улучшающее композицию для кожи
TR201714882A2 (tr) * 2017-10-03 2019-04-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Luli̇konazolün topi̇kal farmasöti̇k kompozi̇syonlari
WO2019155442A1 (en) * 2018-02-12 2019-08-15 Vyome Therapeutics Limited Treatment of gram-negative folliculitis or an inflammation thereof with besifloxacin
KR101961366B1 (ko) * 2018-06-25 2019-03-25 (주) 아이나노 금 나노 입자가 분산 함유되어 있는 항균제 혹은 소취제 조성물, 및 이를 함유한 금나노 함유 제품
JP7467458B2 (ja) * 2018-07-30 2024-04-15 中央研究院 コアセルベート複合化による治療用ナノ粒子および細菌を処理するためのそれらの使用
US20220175827A1 (en) * 2019-04-05 2022-06-09 Northeastern University Biosynthesis of Selenium Nanoparticles Having Antimicrobial Activity
JP7682846B2 (ja) * 2019-07-09 2025-05-26 ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ 抗フケ剤を含むヘアケア組成物
KR102241761B1 (ko) * 2019-08-07 2021-04-16 고려대학교 산학협력단 상온에서 속효성 살균 효과를 갖는 조성물
EP4041153A4 (en) * 2019-10-11 2023-10-25 Piedmont Animal Health Inc. OTIC FORMULATIONS, METHODS AND DEVICES
CN111000744B (zh) * 2020-01-07 2021-10-15 拉芳家化股份有限公司 一种含协同增效去屑组合的洗发香波
CN111286274A (zh) * 2020-03-06 2020-06-16 南雄市双溪丽盈化工涂料有限公司 高闪高透超丰满哑光清面漆
EP4234041A3 (en) * 2020-04-23 2023-09-20 Arch UK Biocides Limited Synergistic preservative/personal care composition containing an alkylene glycol ester
KR102197910B1 (ko) * 2020-08-06 2021-01-05 주식회사 씨엘바이오 피톤치드 함유 살균 및 살바이러스 조성물
CN112205431A (zh) * 2020-09-14 2021-01-12 株洲千金药业股份有限公司 一种抑菌组合物和抑菌型婴幼儿衣物洗液及其制备方法
CN112089684A (zh) * 2020-10-30 2020-12-18 华东医药（西安）博华制药有限公司 左奥硝唑/奥硝唑水包油乳温敏凝胶栓剂及其制备方法
CN112263499B (zh) * 2020-11-27 2023-05-23 佛山市南海东方澳龙制药有限公司 一种具有抗菌功能的动物香波及制备方法
FR3124077B1 (fr) * 2021-06-22 2025-05-02 Univ Nanyang Tech Utilisation d ’ un acide gras à cha î ne courte comme agent antipelliculaire
EP4262711A1 (en) * 2020-12-21 2023-10-25 Nanyang Technological University Use of a short chain fatty acid as antidandruff agent
WO2022197627A1 (en) * 2021-03-15 2022-09-22 Drugarray, Inc. Combination therapy for treating covid-19
WO2022197625A1 (en) * 2021-03-15 2022-09-22 Drugarray, Inc. Combination therapy for treating covid-19
WO2022197626A1 (en) * 2021-03-15 2022-09-22 Drugarray, Inc. Combination therapy for treating covid-19
WO2022258404A1 (en) 2021-06-09 2022-12-15 Unilever Ip Holdings B.V. Topical composition for restoring microbial diversity of scalp
EP4791204A1 (en) * 2023-10-13 2026-08-19 Arxada, LLC Antimicrobial composition
WO2026039712A1 (en) * 2024-08-16 2026-02-19 Arch Uk Biocides Limited Antimicrobial composition comprising an alkylene glycol ester producing a biocidal or biostatic effect on microorganisms on the skin

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4406884A (en) * 1981-06-23 1983-09-27 The Procter & Gamble Company Topical antimicrobial composition
EP0116439A3 (en) 1983-02-02 1986-01-29 Suntory Limited Fatty acid containing hair tonic composition
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
US5198209A (en) * 1992-02-11 1993-03-30 Amway Corporation Conditioning shampoo
ES2068762B1 (es) * 1993-07-21 1995-12-01 Lipotec Sa Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion.
SE9303744D0 (sv) * 1993-11-12 1993-11-12 Astra Ab Pharmaceutical emulsion
ES2094688B1 (es) * 1994-08-08 1997-08-01 Cusi Lab Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
US5624666A (en) 1995-01-20 1997-04-29 The Procter & Gamble Company Anti-dandruff shampoos with particulate active agent and cationic polymer
PL191181B1 (pl) * 1997-12-31 2006-03-31 Choongwae Pharma Corp Sposób wytwarzania doustnego preparatu itrakonazolu i doustny preparat itrakonazolu
FR2774900B1 (fr) * 1998-02-13 2000-03-31 Ceca Sa Shampoings antipelliculaires transparents
FR2780889B1 (fr) * 1998-07-10 2001-08-31 Concept Utilisation d'un inhibiteur du cytochrome p450 eventuellement en association avec un antifongique pour le traitement des mycoses
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6623765B1 (en) * 2000-08-01 2003-09-23 University Of Florida, Research Foundation, Incorporated Microemulsion and micelle systems for solubilizing drugs
US6500861B1 (en) * 2000-08-23 2002-12-31 Michael D. Wider Antimicrobial composition and methods of use in the treatment of disease
US6673373B2 (en) * 2001-02-01 2004-01-06 Carlsbad Technology Inc. Antifungal formulation and the methods for manufacturing and using the same
GB0108082D0 (en) * 2001-03-30 2001-05-23 Novartis Consumer Health Sa Topical composition
US7198794B1 (en) * 2002-02-22 2007-04-03 Lorri Riley Topical formulation for treating fingernails and toenails
TW200407172A (en) 2002-10-17 2004-05-16 Unilever Nv Scalp treatment
US20040202636A1 (en) * 2003-04-11 2004-10-14 Kaczvinsky Joseph Robert Personal care composition containing an antidandruff component and a nonionic surfactant
MX2007006833A (es) * 2004-12-10 2007-10-08 Talima Therapeutics Inc Composiciones y metodos para tratar condiciones de la unidad de una.
CA2599673A1 (en) * 2005-03-08 2006-09-14 Reinhold Oehrlein Metal oxide nanoparticles coated with specific n-acylaminomethylene phosphonates
CA2656146C (en) 2006-07-07 2014-12-09 Unilever Plc Anti-dandruff hair conditioning compositions
EP1923043A1 (en) 2006-11-16 2008-05-21 KPSS-Kao Professional Salon Services GmbH Anti-dandruff conditioner composition
US8226965B2 (en) * 2008-04-25 2012-07-24 Nanobio Corporation Methods of treating fungal, yeast and mold infections
EP2174650A1 (en) * 2008-10-08 2010-04-14 Polichem SA Modified release emulsions for application to skin or vaginal mucosa
WO2010096868A1 (en) * 2009-02-25 2010-09-02 Stiefel Research Australia Pty Ltd Topical foam composition
US8778364B2 (en) * 2009-06-19 2014-07-15 Sun Pharma Advanced Research Company Ltd. Nanodispersion of a drug and process for its preparation
WO2012017349A2 (en) * 2010-08-02 2012-02-09 Ranbaxy Laboratories Limited An improved topical pharmaceutical composition comprising nanonized silver sulfadiazine
CN103108605B (zh) * 2010-09-15 2015-12-09 西尔欧集团 长期抑菌化合物及其在牙科修复材料中的应用
EP2723452A2 (en) * 2011-06-22 2014-04-30 Vyome Biosciences Pvt Ltd Conjugate-based antifungal and antibacterial prodrugs

Also Published As

Publication number Publication date
JP2016516765A (ja) 2016-06-09
WO2014167554A3 (en) 2014-12-24
KR20150138392A (ko) 2015-12-09
JP2019031561A (ja) 2019-02-28
KR101862448B1 (ko) 2018-05-29
AU2014252157B2 (en) 2017-05-11
CN105263525A (zh) 2016-01-20
AU2014252157A1 (en) 2015-11-05
EA201591954A1 (ru) 2016-04-29
US20160058775A1 (en) 2016-03-03
HK1220624A1 (zh) 2017-05-12
EP2983714A2 (en) 2016-02-17
WO2014167554A2 (en) 2014-10-16

Similar Documents

Publication Publication Date Title
JP2019031561A (ja) 抗菌薬の組成物および製剤、その製造法および微生物感染症の治療方法
JP6653342B2 (ja) 真菌感染症の治療用の局所用オイル組成物
US20220288086A1 (en) Treatment for bacterial infection
KR20190037229A (ko) 상승효과적 항진균 조성물 및 그의 방법
JP2016516765A5 (enExample)
JP2011529038A5 (enExample)
WO2012017349A2 (en) An improved topical pharmaceutical composition comprising nanonized silver sulfadiazine
CN108137612A (zh) 软性抗胆碱能药类似物的制剂
JP2011093835A (ja) 皮膚外用剤
JP7744739B2 (ja) アラントイン及び／又はその誘導体の安定化方法
JP6180822B2 (ja) 医薬組成物
WO2025222091A1 (en) Poly inflammatory kinase inhibitors and pharmaceutical compositions
HK40064465A (en) Treatments for resistant acne
WO2021189077A1 (en) Methods for treating acne
WO2016133471A1 (en) A topical composition comprising mupirocin and dexpanthenol
TH4847Y (th) สารผสมทางเภสัชกรรมสำหรับบำบัดอาการปวด
TH4847U (th) สารผสมทางเภสัชกรรมสำหรับบำบัดอาการปวด
RU2011106753A (ru) Способы введения топических противогрибковых препаратов для лечения грибковых инфекций

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170117

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170117

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170906

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20171203

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20180205

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180322

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20180702

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181101

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20190118

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190227

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190228

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20190318

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20190408

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20190415

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190627

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190617

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190911

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20190408

R150 Certificate of patent or registration of utility model

Ref document number: 6589086

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees