JP6585605B2 - 有機化合物における、またはそれに関する改善 - Google Patents

有機化合物における、またはそれに関する改善 Download PDF

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JP6585605B2
JP6585605B2 JP2016549636A JP2016549636A JP6585605B2 JP 6585605 B2 JP6585605 B2 JP 6585605B2 JP 2016549636 A JP2016549636 A JP 2016549636A JP 2016549636 A JP2016549636 A JP 2016549636A JP 6585605 B2 JP6585605 B2 JP 6585605B2
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alkyl
nitroso
carbon
mnu
substrate
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JP2016538335A5 (enExample
JP2016538335A (ja
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シュローダー，フリッチョフ
ルエティ，ファビアン
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Amyris Inc
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Amyris Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/02—Addition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22—Organic complexes
    • B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
    • B01J31/2208—Oxygen, e.g. acetylacetonates
    • B01J31/2213—At least two complexing oxygen atoms present in an at least bidentate or bridging ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/08—Isomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2/00—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms
    • C07C2/86—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms by condensation between a hydrocarbon and a non-hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/553—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/30—Addition reactions at carbon centres, i.e. to either C-C or C-X multiple bonds
    • B01J2231/32—Addition reactions to C=C or C-C triple bonds
    • B01J2231/324—Cyclisations via conversion of C-C multiple to single or less multiple bonds, e.g. cycloadditions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/824—Palladium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2531/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • C07C2531/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • C07C2531/22—Organic complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/50—Spiro compounds

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2016549636A 2013-10-25 2014-10-24 有機化合物における、またはそれに関する改善 Active JP6585605B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1318886.7 2013-10-25
GBGB1318886.7A GB201318886D0 (en) 2013-10-25 2013-10-25 Improvements i or relating to organic compounds
PCT/EP2014/072882 WO2015059290A1 (en) 2013-10-25 2014-10-24 Improvements in or relating to organic compounds

Publications (3)

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JP2016538335A JP2016538335A (ja) 2016-12-08
JP2016538335A5 JP2016538335A5 (enExample) 2017-11-30
JP6585605B2 true JP6585605B2 (ja) 2019-10-02

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JP2016549636A Active JP6585605B2 (ja) 2013-10-25 2014-10-24 有機化合物における、またはそれに関する改善

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US (2) US9718741B2 (enExample)
EP (1) EP3060535B1 (enExample)
JP (1) JP6585605B2 (enExample)
CN (1) CN105658604B (enExample)
ES (1) ES2822673T3 (enExample)
GB (1) GB201318886D0 (enExample)
IL (1) IL244929B (enExample)
MX (1) MX381408B (enExample)
SG (1) SG11201602725UA (enExample)
WO (1) WO2015059290A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201507170D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Process
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201516396D0 (en) 2015-09-16 2015-10-28 Givaudan Sa Improvements in or relating to organic compounds
GB201618090D0 (en) 2016-10-26 2016-12-07 Givaudan Sa Product
GB201720211D0 (en) * 2017-12-05 2018-01-17 Givaudan Sa Improvements in or relating to organic compounds
CN108484347B (zh) * 2018-04-28 2021-02-05 江苏八巨药业有限公司 一种末端异戊二烯类化合物环丙烷化的制备方法
GB201810514D0 (en) 2018-06-27 2018-08-15 Givaudan Sa Improvements in or relating to organic compounds
JP7441863B2 (ja) * 2019-07-02 2024-03-01 アシムケム ラボラトリーズ （ティエンジン） カンパニー リミテッド シクロプロパン系化合物の連続合成方法及び装置
CN110577484A (zh) * 2019-07-02 2019-12-17 凯莱英医药集团（天津）股份有限公司 环丙烷类化合物连续合成的方法及装置
CN111574411A (zh) * 2020-04-24 2020-08-25 常州齐晖药业有限公司 一种地克珠利杂质b的制备方法
CN111517991A (zh) * 2020-04-24 2020-08-11 常州齐晖药业有限公司 一种地克珠利杂质a的制备方法
CN113480404A (zh) * 2021-06-30 2021-10-08 中昊(大连)化工研究设计院有限公司 一种环丙基溴合成的新方法

Family Cites Families (15)

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US4650881A (en) 1985-04-01 1987-03-17 Iowa State University Research Foundation, Inc. Synthesis of isocoumarins via thallation-olefination of arenes
JPS62129240A (ja) * 1985-11-29 1987-06-11 Tokyo Tanabe Co Ltd ４′−シクロプロピルフエノン誘導体
DE4327748B4 (de) * 1993-08-18 2006-07-20 Merck Patent Gmbh Cyclopropyl- und Cyclobutyl-Derivate
JP3385264B2 (ja) * 1995-04-11 2003-03-10 三井化学株式会社 置換チオフェン誘導体およびこれを有効成分とする農園芸用殺菌剤
ATE201016T1 (de) * 1995-06-09 2001-05-15 Hoffmann La Roche Pyrimidindion-, pyrimidintrion-, triazindion- derivate als alpha-1-adrenergische rezeptorantagonisten
US5854405A (en) * 1997-11-13 1998-12-29 Aerojet-General Corporation Continuous process for diazomethane from an n-methyl-n-nitrosoamine and from methylurea through n-methyl-n-nitrosourea
FR2801051B1 (fr) * 1999-11-17 2001-12-14 Adir Nouveaux composes aminopyrroline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1921847B (zh) * 2004-02-24 2010-06-16 三共株式会社 氨基醇化合物
NZ568488A (en) * 2005-12-22 2011-07-29 High Point Pharmaceuticals Llc Phenoxy acetic acids as PPAR delta activators
WO2010131147A1 (en) 2009-05-12 2010-11-18 Pfizer Limited Cyclobutenedione derivatives
WO2012059485A2 (en) * 2010-11-01 2012-05-10 Dsm Ip Assets B.V. Continuous production and reaction of a diazo compound
US8722916B2 (en) * 2010-12-01 2014-05-13 Rigel Pharmaceuticals, Inc. Cyclopropyl MIDA boronate
JP2014088326A (ja) * 2011-02-22 2014-05-15 Astellas Pharma Inc ポリペプチド化合物
US20120226041A1 (en) * 2011-03-04 2012-09-06 The Board Of Trustees Of The University Of Illinois Catalysts and boronate esters
EP2755962B1 (en) * 2011-09-13 2017-03-01 Glaxosmithkline LLC Azaindazoles

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Publication number Publication date
GB201318886D0 (en) 2013-12-11
ES2822673T3 (es) 2021-05-04
IL244929B (en) 2019-06-30
SG11201602725UA (en) 2016-05-30
US20160280615A1 (en) 2016-09-29
EP3060535A1 (en) 2016-08-31
MX2016005053A (es) 2016-08-17
CN105658604A (zh) 2016-06-08
EP3060535B1 (en) 2020-08-05
US9718741B2 (en) 2017-08-01
US20170283342A1 (en) 2017-10-05
WO2015059290A1 (en) 2015-04-30
CN105658604B (zh) 2019-10-25
IL244929A0 (en) 2016-05-31
MX381408B (es) 2025-03-12
JP2016538335A (ja) 2016-12-08

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