JP6580028B2 - 生育可能なヒト皮膚代用物の凍結保存 - Google Patents

生育可能なヒト皮膚代用物の凍結保存 Download PDF

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Publication number
JP6580028B2
JP6580028B2 JP2016501891A JP2016501891A JP6580028B2 JP 6580028 B2 JP6580028 B2 JP 6580028B2 JP 2016501891 A JP2016501891 A JP 2016501891A JP 2016501891 A JP2016501891 A JP 2016501891A JP 6580028 B2 JP6580028 B2 JP 6580028B2
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tissue
skin equivalent
cryopreserved
solution
cryoprotectant
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JP2016512434A (ja
JP2016512434A5 (enExample
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アレン−ホフマン,ビー.リン
シー. パーンスティル,ジョン
シー. パーンスティル,ジョン
アール. グラッツ,ケネス
アール. グラッツ,ケネス
アール. カマー,アレン
アール. カマー,アレン
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ストラタテック コーポレーション
ストラタテック コーポレーション
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/125Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
JP2016501891A 2013-03-13 2014-03-13 生育可能なヒト皮膚代用物の凍結保存 Active JP6580028B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361779661P 2013-03-13 2013-03-13
US61/779,661 2013-03-13
PCT/US2014/025599 WO2014160000A1 (en) 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019154515A Division JP7220640B2 (ja) 2013-03-13 2019-08-27 生育可能なヒト皮膚代用物の凍結保存

Publications (3)

Publication Number Publication Date
JP2016512434A JP2016512434A (ja) 2016-04-28
JP2016512434A5 JP2016512434A5 (enExample) 2017-04-13
JP6580028B2 true JP6580028B2 (ja) 2019-09-25

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JP2016501891A Active JP6580028B2 (ja) 2013-03-13 2014-03-13 生育可能なヒト皮膚代用物の凍結保存
JP2019154515A Active JP7220640B2 (ja) 2013-03-13 2019-08-27 生育可能なヒト皮膚代用物の凍結保存

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US (3) US10091983B2 (enExample)
EP (3) EP2967836B1 (enExample)
JP (2) JP6580028B2 (enExample)
AU (4) AU2014244264B2 (enExample)
CA (2) CA2905656C (enExample)
DK (2) DK2967836T3 (enExample)
ES (2) ES2705043T3 (enExample)
IL (1) IL241448B (enExample)
PT (2) PT2967836T (enExample)
WO (1) WO2014160000A1 (enExample)

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US9777064B2 (en) 2015-03-17 2017-10-03 Chimera Bioengineering, Inc. Smart CAR devices, DE CAR polypeptides, side CARs and uses thereof
US11052111B2 (en) 2015-12-08 2021-07-06 Chimera Bioengineering, Inc. Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses
US10222369B2 (en) 2016-05-17 2019-03-05 Chimera Bioengineering, Inc. Methods for making novel antigen binding domains
EP4342978A3 (en) 2016-09-01 2024-07-03 Chimera Bioengineering Inc. Gold optimized car t-cells
CN111989108B (zh) 2018-02-13 2024-07-16 嵌合体生物工程公司 利用rna去稳定元件协调基因表达
IL280610B2 (en) 2018-08-31 2024-08-01 Wisconsin Alumni Res Found Fabrication of vascular grafts seeded with arterial endothelial cells
JP7600110B2 (ja) * 2018-11-22 2024-12-16 ヴィトラフィー ライフ サイエンシズ リミテッド 生物学的製品を冷凍するための装置
EP4013431A4 (en) 2019-08-18 2024-05-01 Chimera Bioengineering, Inc. Combination therapy with gold controlled transgenes
JP2022549688A (ja) * 2019-09-27 2022-11-28 ストラタテック コーポレーション 急性創傷を治療し、転帰を改善するための方法
CN114836291B (zh) * 2021-02-01 2025-11-21 深圳拜尔洛克生物技术有限公司 生物材料解冻复苏的系统及其方法
AU2022282461A1 (en) * 2021-05-28 2023-11-16 Stratatech Corporation Tissue container systems
AU2022280097A1 (en) * 2021-05-28 2023-11-16 Stratatech Corporation Allogeneic cultured keratinocyte products
WO2023056194A2 (en) 2021-09-29 2023-04-06 Chimera Bioengineering, Inc. Compositions and methods for anti-tnmuc1 gold car t-cells

Family Cites Families (30)

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US4485096A (en) 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
IL95429A (en) 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
RU2135191C1 (ru) 1990-04-24 1999-08-27 Ортек Интернэшнл, Инк. Композиционный эквивалент живой кожи, способ его получения, тест-набор
IT1248934B (it) 1990-06-01 1995-02-11 Fidia Spa Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets
US5518878A (en) * 1993-09-15 1996-05-21 Organogenesis Inc. Cryopreservation of cultured skin or cornea equivalents with agitation
US5891617A (en) * 1993-09-15 1999-04-06 Organogenesis Inc. Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing
JPH10509610A (ja) * 1994-11-09 1998-09-22 クリ・ハークチ,ワリド 創傷修復用包帯およびそれらの保存法
IT1281870B1 (it) 1995-04-27 1998-03-03 Fidia Advanced Biopolymers Srl Pelle artificiale umana costituita da materiali biocompatibili a base di derivati dell'acido ialuronico
US5693332C1 (en) 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
US5689961A (en) * 1996-01-30 1997-11-25 Organogenesis Inc. Ice seeding apparatus for cryopreservation systems
US5968546A (en) 1997-05-16 1999-10-19 Baur; Marcus Keratinocyte culture from precursor cells
US5989837A (en) 1998-07-13 1999-11-23 Wisconsin Alumni Research Foundation Immortalized human keratinocyte cell line
IL157532A0 (en) * 2000-12-27 2004-03-28 Ortec International Inc Processes for making cryopreserved composite living constructs and products resulting therefrom
US6974697B2 (en) 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
NZ549526A (en) 2001-03-02 2009-06-26 Stratatech Corp Human skin equivalents comprising near diploid immortalized keratinocyte cells (NIKS)
WO2003093418A2 (en) 2002-04-30 2003-11-13 Stratech Corporation Keratinocytes expressing exogenous angiogenic growth factors
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WO2005012492A2 (en) 2003-08-01 2005-02-10 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
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US9163076B2 (en) 2005-03-01 2015-10-20 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
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WO2009065005A1 (en) * 2007-11-14 2009-05-22 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
AU2009313656B2 (en) 2008-11-04 2014-02-20 Stratatech Corporation Dried and irradiated skin equivalents for ready use
US20100330046A1 (en) 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12
WO2013062994A1 (en) 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating full thickness burn injuries
US20130108683A1 (en) * 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating partial and full thickness wounds and injuries
ES2705043T3 (es) * 2013-03-13 2019-03-21 Stratatech Corp Criopreservación de sustitutos de piel humana viables

Also Published As

Publication number Publication date
AU2019232795B2 (en) 2021-08-12
JP2016512434A (ja) 2016-04-28
AU2021261937B2 (en) 2023-11-16
US11297829B2 (en) 2022-04-12
WO2014160000A1 (en) 2014-10-02
PT2967836T (pt) 2019-01-21
AU2014244264A1 (en) 2015-10-01
DK3470018T3 (da) 2021-10-04
DK2967836T3 (en) 2019-01-28
PT3470018T (pt) 2021-10-04
EP2967836B1 (en) 2018-10-10
US20190000071A1 (en) 2019-01-03
AU2021261937A1 (en) 2021-12-02
CA2905656A1 (en) 2014-10-02
US10091983B2 (en) 2018-10-09
JP2019195344A (ja) 2019-11-14
US20220192181A1 (en) 2022-06-23
AU2017206148A1 (en) 2017-08-03
JP7220640B2 (ja) 2023-02-10
EP2967836A4 (en) 2016-11-23
ES2705043T3 (es) 2019-03-21
EP2967836A1 (en) 2016-01-20
AU2014244264B2 (en) 2017-04-20
CA3071928A1 (en) 2014-10-02
EP3470018A1 (en) 2019-04-17
EP3900534A1 (en) 2021-10-27
CA2905656C (en) 2020-04-14
IL241448B (en) 2019-02-28
ES2893844T3 (es) 2022-02-10
US20140271583A1 (en) 2014-09-18
AU2019232795A1 (en) 2019-10-10
EP3470018B1 (en) 2021-07-28
IL241448A0 (en) 2015-11-30
AU2017206148B2 (en) 2019-06-20

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