CA3071928A1 - Cryopreservation of viable human skin substitutes - Google Patents
Cryopreservation of viable human skin substitutes Download PDFInfo
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- CA3071928A1 CA3071928A1 CA3071928A CA3071928A CA3071928A1 CA 3071928 A1 CA3071928 A1 CA 3071928A1 CA 3071928 A CA3071928 A CA 3071928A CA 3071928 A CA3071928 A CA 3071928A CA 3071928 A1 CA3071928 A1 CA 3071928A1
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- skin equivalent
- cryopreserved
- cryoprotectant
- tissues
- kit
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- 239000013641 positive control Substances 0.000 description 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
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| CA2905656A CA2905656C (en) | 2013-03-13 | 2014-03-13 | Cryopreservation of viable human skin substitutes |
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| CA2905656A Division CA2905656C (en) | 2013-03-13 | 2014-03-13 | Cryopreservation of viable human skin substitutes |
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|---|---|
| CA3071928A1 true CA3071928A1 (en) | 2014-10-02 |
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| CA2905656A Active CA2905656C (en) | 2013-03-13 | 2014-03-13 | Cryopreservation of viable human skin substitutes |
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| EP (3) | EP3900534A1 (enExample) |
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| ES (2) | ES2705043T3 (enExample) |
| IL (1) | IL241448B (enExample) |
| PT (2) | PT3470018T (enExample) |
| WO (1) | WO2014160000A1 (enExample) |
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| EP3900534A1 (en) * | 2013-03-13 | 2021-10-27 | Stratatech Corporation | Method for warming cryoconserved human skin substitutes |
| JP6826975B2 (ja) * | 2014-07-09 | 2021-02-10 | ジェネンテック， インコーポレイテッド | 細胞バンクの解凍復元を改善するためのｐＨ調整 |
| WO2016149254A1 (en) | 2015-03-17 | 2016-09-22 | Chimera Bioengineering, Inc. | Smart car devices, de car polypeptides, side cars and uses thereof |
| US11052111B2 (en) | 2015-12-08 | 2021-07-06 | Chimera Bioengineering, Inc. | Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses |
| US10222369B2 (en) | 2016-05-17 | 2019-03-05 | Chimera Bioengineering, Inc. | Methods for making novel antigen binding domains |
| JP7045378B2 (ja) | 2016-09-01 | 2022-03-31 | キメラ・バイオエンジニアリング，インコーポレーテッド | Ｇｏｌｄ最適化ＣＡＲ Ｔ細胞 |
| WO2019160815A1 (en) | 2018-02-13 | 2019-08-22 | Chimera Bioengineering, Inc. | Coordinating gene expression using rna destabilizing elements |
| CA3109300C (en) | 2018-08-31 | 2024-05-14 | Wisconsin Alumni Research Foundation | Generating arterial endothelial cell-seeded vascular grafts |
| CN113424002B (zh) * | 2018-11-22 | 2023-12-01 | 维特拉菲生命科学有限公司 | 冷冻生物产品的方法和装置 |
| EP4013431A4 (en) | 2019-08-18 | 2024-05-01 | Chimera Bioengineering, Inc. | Combination therapy with gold controlled transgenes |
| US20220347353A1 (en) * | 2019-09-27 | 2022-11-03 | Stratatech Corporation | Methods for treating acute wounds and improving outcomes |
| CN114836291B (zh) * | 2021-02-01 | 2025-11-21 | 深圳拜尔洛克生物技术有限公司 | 生物材料解冻复苏的系统及其方法 |
| AU2022282461A1 (en) * | 2021-05-28 | 2023-11-16 | Stratatech Corporation | Tissue container systems |
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| US4485096A (en) | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
| IL95429A (en) | 1989-09-15 | 1997-09-30 | Organogenesis | Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production |
| USRE35399E (en) | 1990-04-24 | 1996-12-10 | Eisenberg; Mark | Composite living skin equivalents |
| IT1248934B (it) | 1990-06-01 | 1995-02-11 | Fidia Spa | Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle |
| US5145770A (en) * | 1990-06-04 | 1992-09-08 | Biosurface Technology, Inc. | Cryopreservation of cultured epithelial sheets |
| US5891617A (en) * | 1993-09-15 | 1999-04-06 | Organogenesis Inc. | Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing |
| US5518878A (en) * | 1993-09-15 | 1996-05-21 | Organogenesis Inc. | Cryopreservation of cultured skin or cornea equivalents with agitation |
| AU4106796A (en) | 1994-11-09 | 1996-06-06 | Federico Castro Munozledo | Wound repair dressings and methods for their preservation |
| IT1281870B1 (it) * | 1995-04-27 | 1998-03-03 | Fidia Advanced Biopolymers Srl | Pelle artificiale umana costituita da materiali biocompatibili a base di derivati dell'acido ialuronico |
| US5693332C1 (en) | 1995-08-11 | 2001-01-09 | Univ California | Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure |
| US5689961A (en) | 1996-01-30 | 1997-11-25 | Organogenesis Inc. | Ice seeding apparatus for cryopreservation systems |
| US5968546A (en) | 1997-05-16 | 1999-10-19 | Baur; Marcus | Keratinocyte culture from precursor cells |
| US5989837A (en) | 1998-07-13 | 1999-11-23 | Wisconsin Alumni Research Foundation | Immortalized human keratinocyte cell line |
| WO2002058588A2 (en) * | 2000-12-27 | 2002-08-01 | Ortec International, Inc. | Processes for making cryopreserved composite living constructs and products resulting therefrom |
| NZ549528A (en) | 2001-03-02 | 2008-04-30 | Stratatech Corp | Method of making skin equivalents having improved barrier function |
| US6974697B2 (en) | 2001-03-02 | 2005-12-13 | Stratech Corporation | Skin substitutes with improved barrier function |
| DE60332256D1 (de) | 2002-04-30 | 2010-06-02 | Stratatech Corp | Exogene angiogene wachstumsfaktoren exprimierende keratinozyten |
| WO2004013606A2 (en) | 2002-08-02 | 2004-02-12 | Stratatech Corporation | Species specific dna detection |
| EP1633858A4 (en) * | 2003-05-30 | 2006-11-02 | Stratatech Corp | STORAGE OF ORGANS AT ROOM TEMPERATURE |
| EP2481287B1 (en) | 2003-08-01 | 2016-07-20 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| WO2005041880A2 (en) * | 2003-10-29 | 2005-05-12 | Science & Technology Corporation @ Unm | RhPV AS A MODEL FOR HPV-INDUCED CANCERS |
| CA2600177C (en) | 2005-03-01 | 2011-06-14 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| US9295543B2 (en) | 2005-03-17 | 2016-03-29 | Stratatech Corporation | Skin substitutes with improved purity |
| KR100803384B1 (ko) | 2007-01-15 | 2008-02-13 | 한스바이오메드 주식회사 | 피부조직의 장기 보관 방법 |
| DK2215212T3 (da) | 2007-11-14 | 2017-11-27 | Stratatech Corp | Kold opbevaring af organotypisk dyrkede hudækvivalenter til kliniske anvendelser |
| ES2621324T3 (es) | 2008-11-04 | 2017-07-03 | Stratatech Corporation | Equivalentes de piel secos e irradiados listos para su uso |
| WO2010135655A2 (en) | 2009-05-21 | 2010-11-25 | Stratatech Corporation | Human skin substitutes expressing il-12 |
| US20130108670A1 (en) * | 2011-10-25 | 2013-05-02 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating full thickness burn injuries |
| US20130108683A1 (en) | 2011-10-25 | 2013-05-02 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating partial and full thickness wounds and injuries |
| EP3900534A1 (en) * | 2013-03-13 | 2021-10-27 | Stratatech Corporation | Method for warming cryoconserved human skin substitutes |
-
2014
- 2014-03-13 EP EP21177142.3A patent/EP3900534A1/en not_active Withdrawn
- 2014-03-13 DK DK18197432.0T patent/DK3470018T3/da active
- 2014-03-13 JP JP2016501891A patent/JP6580028B2/ja active Active
- 2014-03-13 EP EP18197432.0A patent/EP3470018B1/en active Active
- 2014-03-13 PT PT18197432T patent/PT3470018T/pt unknown
- 2014-03-13 EP EP14775892.4A patent/EP2967836B1/en active Active
- 2014-03-13 AU AU2014244264A patent/AU2014244264B2/en not_active Ceased
- 2014-03-13 CA CA3071928A patent/CA3071928A1/en active Pending
- 2014-03-13 ES ES14775892T patent/ES2705043T3/es active Active
- 2014-03-13 CA CA2905656A patent/CA2905656C/en active Active
- 2014-03-13 US US14/208,439 patent/US10091983B2/en active Active
- 2014-03-13 PT PT14775892T patent/PT2967836T/pt unknown
- 2014-03-13 ES ES18197432T patent/ES2893844T3/es active Active
- 2014-03-13 DK DK14775892.4T patent/DK2967836T3/en active
- 2014-03-13 WO PCT/US2014/025599 patent/WO2014160000A1/en not_active Ceased
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2015
- 2015-09-10 IL IL241448A patent/IL241448B/en active IP Right Grant
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2017
- 2017-07-17 AU AU2017206148A patent/AU2017206148B2/en not_active Ceased
-
2018
- 2018-09-05 US US16/122,598 patent/US11297829B2/en active Active
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2019
- 2019-08-27 JP JP2019154515A patent/JP7220640B2/ja active Active
- 2019-09-17 AU AU2019232795A patent/AU2019232795B2/en not_active Ceased
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2021
- 2021-11-05 AU AU2021261937A patent/AU2021261937B2/en not_active Ceased
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2022
- 2022-03-14 US US17/694,245 patent/US20220192181A1/en not_active Abandoned
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