JP6567654B2 - ４−置換ピリジン−２，６−ジカルボン酸誘導体とその製造方法 - Google Patents
４−置換ピリジン−２，６−ジカルボン酸誘導体とその製造方法 Download PDFInfo
- Publication number
- JP6567654B2 JP6567654B2 JP2017513162A JP2017513162A JP6567654B2 JP 6567654 B2 JP6567654 B2 JP 6567654B2 JP 2017513162 A JP2017513162 A JP 2017513162A JP 2017513162 A JP2017513162 A JP 2017513162A JP 6567654 B2 JP6567654 B2 JP 6567654B2
- Authority
- JP
- Japan
- Prior art keywords
- dicarboxylate
- pyridine
- dimethyl
- diethyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 *C(C1)C=C(C(*)=O)OC1(C(*)=O)O Chemical compound *C(C1)C=C(C(*)=O)OC1(C(*)=O)O 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462048203P | 2014-09-09 | 2014-09-09 | |
| US62/048,203 | 2014-09-09 | ||
| PCT/JP2015/004588 WO2016038890A1 (en) | 2014-09-09 | 2015-09-09 | 4-substituted pyridine-2,6-dicarboxylic acid derivatives and method of preparing same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017526705A JP2017526705A (ja) | 2017-09-14 |
| JP2017526705A5 JP2017526705A5 (cg-RX-API-DMAC7.html) | 2019-08-15 |
| JP6567654B2 true JP6567654B2 (ja) | 2019-08-28 |
Family
ID=55458659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017513162A Active JP6567654B2 (ja) | 2014-09-09 | 2015-09-09 | ４−置換ピリジン−２，６−ジカルボン酸誘導体とその製造方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20170217889A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3191451B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6567654B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016038890A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115286567B (zh) * | 2022-08-12 | 2024-04-19 | 镇江中智化学科技有限公司 | 一锅法合成3-溴吡啶 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4368576B2 (ja) * | 2002-12-20 | 2009-11-18 | 財団法人くまもとテクノ産業財団 | ジチオール化合物 |
| US8071626B2 (en) * | 2003-12-18 | 2011-12-06 | Wallac Oy | Chelating agents and highly luminescent and stable chelates and their use |
| JP5178738B2 (ja) * | 2006-12-20 | 2013-04-10 | メルク・シャープ・アンド・ドーム・コーポレーション | 新規なｊｎｋ阻害剤 |
| JPWO2012102297A1 (ja) * | 2011-01-26 | 2014-06-30 | 杏林製薬株式会社 | ピラゾロピリジン誘導体、またはその薬理学的に許容される塩 |
| JP6161136B2 (ja) * | 2012-10-12 | 2017-07-12 | 学校法人沖縄科学技術大学院大学学園 | ジヒドロ−２ｈ−ピラン誘導体の製造方法 |
-
2015
- 2015-09-09 US US15/509,721 patent/US20170217889A1/en not_active Abandoned
- 2015-09-09 WO PCT/JP2015/004588 patent/WO2016038890A1/en not_active Ceased
- 2015-09-09 JP JP2017513162A patent/JP6567654B2/ja active Active
- 2015-09-09 EP EP15840917.7A patent/EP3191451B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016038890A1 (en) | 2016-03-17 |
| EP3191451A4 (en) | 2018-03-14 |
| EP3191451B1 (en) | 2019-06-05 |
| JP2017526705A (ja) | 2017-09-14 |
| EP3191451A1 (en) | 2017-07-19 |
| US20170217889A1 (en) | 2017-08-03 |
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