JP6525877B2 - 反応チューブ - Google Patents

反応チューブ Download PDF

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Publication number
JP6525877B2
JP6525877B2 JP2015534674A JP2015534674A JP6525877B2 JP 6525877 B2 JP6525877 B2 JP 6525877B2 JP 2015534674 A JP2015534674 A JP 2015534674A JP 2015534674 A JP2015534674 A JP 2015534674A JP 6525877 B2 JP6525877 B2 JP 6525877B2
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JP
Japan
Prior art keywords
fluid
chamber
well
reaction tube
planar
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JP2015534674A
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English (en)
Japanese (ja)
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JP2015532094A (ja
JP2015532094A5 (enExample
Inventor
ユ‐ミン チャン、
ユ‐ミン チャン、
ドグ ドリティ、
ドグ ドリティ、
ダスティン ディケンス、
ダスティン ディケンス、
ジェニファー グラス、
ジェニファー グラス、
アタ、 ロウエル ヴァン
アタ、 ロウエル ヴァン
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セフェィド
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Publication of JP2015532094A5 publication Critical patent/JP2015532094A5/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Food Science & Technology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • External Artificial Organs (AREA)
JP2015534674A 2012-09-26 2013-09-26 反応チューブ Active JP6525877B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261706115P 2012-09-26 2012-09-26
US61/706,115 2012-09-26
US13/843,739 2013-03-15
US13/843,739 US9914968B2 (en) 2012-09-26 2013-03-15 Honeycomb tube
PCT/US2013/062042 WO2014052671A1 (en) 2012-09-26 2013-09-26 Honeycomb tube

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019087554A Division JP2019141092A (ja) 2012-09-26 2019-05-07 ハニカムチューブ

Publications (3)

Publication Number Publication Date
JP2015532094A JP2015532094A (ja) 2015-11-09
JP2015532094A5 JP2015532094A5 (enExample) 2016-11-17
JP6525877B2 true JP6525877B2 (ja) 2019-06-05

Family

ID=50339439

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015534674A Active JP6525877B2 (ja) 2012-09-26 2013-09-26 反応チューブ
JP2019087554A Pending JP2019141092A (ja) 2012-09-26 2019-05-07 ハニカムチューブ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019087554A Pending JP2019141092A (ja) 2012-09-26 2019-05-07 ハニカムチューブ

Country Status (12)

Country Link
US (10) US9914968B2 (enExample)
JP (2) JP6525877B2 (enExample)
KR (1) KR102214419B1 (enExample)
CN (2) CN105051546A (enExample)
AP (1) AP2015008394A0 (enExample)
AU (1) AU2013323428B2 (enExample)
BR (1) BR112015006566B1 (enExample)
CA (1) CA2886484C (enExample)
EA (1) EA031989B1 (enExample)
MX (1) MX363399B (enExample)
WO (1) WO2014052671A1 (enExample)
ZA (1) ZA201502463B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12203135B2 (en) 2012-09-26 2025-01-21 Cepheid Honeycomb tube

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6200948B2 (ja) 2012-05-25 2017-09-20 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル マイクロ流体デバイス
SG2012075792A (en) * 2012-10-09 2014-05-29 Jn Medsys Pte Ltd An improved device and method
CN105229136B (zh) * 2013-03-15 2018-03-16 西菲伊德公司 多室盖设备
WO2015069743A1 (en) * 2013-11-05 2015-05-14 Biofire Diagnostics, Llc Induction pcr
US11587686B2 (en) 2014-10-16 2023-02-21 Cepheid Biosecurity screening system and method
JP2018518655A (ja) * 2015-04-03 2018-07-12 アボット・ラボラトリーズAbbott Laboratories サンプル分析用デバイス及び方法
US10870111B2 (en) * 2015-07-22 2020-12-22 The University Of North Carolina At Chapel Hill Fluidic devices with bead well geometries with spatially separated bead retention and signal detection segments and related methods
US10797567B2 (en) 2015-07-23 2020-10-06 Life Technologies Corporation Rotor assembly including a housing for a sensor array component and methods for using same
AU2016297866B2 (en) 2015-07-24 2021-10-21 Cepheid Molecular diagnostic assay system
JP6808940B2 (ja) * 2016-01-29 2021-01-06 凸版印刷株式会社 アレイデバイス、生体分子解析用キット及び溶媒の封止方法
GB2554377A (en) * 2016-09-23 2018-04-04 Dnanudge Ltd Method and apparatus for analysing a biological sample
KR101997116B1 (ko) * 2016-10-14 2019-07-05 연세대학교 산학협력단 Kras 유전자에 상보적인 가이드 rna 및 이의 용도
CN210916083U (zh) * 2017-01-23 2020-07-03 长沙深宇生物科技有限公司 直接定量pcr装置
CA3056256A1 (en) * 2017-03-29 2018-10-04 Cornell University Devices, processes, and systems for determination of nucleic acid sequence, expression, copy number, or methylation changes using combined nuclease, ligase, polymerase, and sequencing reactions
US20200102587A1 (en) * 2017-04-05 2020-04-02 Hitachi High-Technologies Corporation Nucleic acid amplification method and nucleic acid analyzer
WO2019131592A1 (ja) * 2017-12-26 2019-07-04 凸版印刷株式会社 標的分子の検出における偽陰性判定の発生を抑制する方法および検出デバイス
PL425106A1 (pl) 2018-03-30 2019-10-07 Bacteromic Spółka Z Ograniczoną Odpowiedzialnością Chip mikroprzepływowy
CN111218383B (zh) * 2018-11-26 2025-09-09 杭州比格飞序生物科技有限公司 一种核酸提取装置及其方法
WO2020126985A1 (en) * 2018-12-20 2020-06-25 Imec Vzw Addressable micro-reaction chamber array
US11976269B2 (en) * 2019-03-18 2024-05-07 Cellular Research, Inc. Precise delivery of components into fluids
KR20210142690A (ko) 2019-03-21 2021-11-25 셜록 바이오사이언스, 인크. 시스템
JP7280101B2 (ja) * 2019-04-23 2023-05-23 株式会社日立製作所 測定セル製造方法、測定セル
ES2954784T3 (es) * 2019-05-08 2023-11-24 Dnae Diagnostics Ltd Amplificación de ADN en fase de solución y en fase sólida combinadas
JP7517336B2 (ja) * 2019-05-30 2024-07-17 Toppanホールディングス株式会社 ウェルに液体を導入する方法
US10820847B1 (en) 2019-08-15 2020-11-03 Talis Biomedical Corporation Diagnostic system
CN119216002A (zh) * 2019-09-23 2024-12-31 塞弗德公司 具有试剂端口的多腔室盖装置
US12054320B2 (en) 2019-09-23 2024-08-06 Cepheid Multi-chambered lid apparatus with reagent port
US11254979B2 (en) 2020-06-01 2022-02-22 Shaheen Innovations Holding Limited Systems and devices for infectious disease screening
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
CN111190021B (zh) * 2020-02-22 2023-08-11 武汉泰沃科技有限责任公司 一种生物样品处理盒
US12687470B2 (en) 2020-04-06 2026-07-21 Shaheen Innovations Holding Limited Cell lysis systems and methods
AU2021285405B2 (en) 2020-06-01 2026-06-18 Shaheen Innovations Holding Limited An infectious disease screening system
IL298682B2 (en) 2020-06-01 2026-02-01 Shaheen Innovations Holding Ltd Infectious disease scanning device
KR102961294B1 (ko) * 2020-09-29 2026-05-06 주식회사 씨젠 핵산 반응 챔버, 이를 이용한 핵산 반응 방법 및 이를 포함하는 샘플 처리용 카트리지
EP4278430A1 (en) 2021-01-13 2023-11-22 Cepheid Lossy mechatronic systems and methods of estimation
CN115836222A (zh) * 2021-05-27 2023-03-21 京东方科技集团股份有限公司 检测芯片及其制备方法和进样方法
US20230043483A1 (en) * 2021-07-09 2023-02-09 Cepheld High-level multiplexing reaction vessel, reagent spotting device and associated methods
JP2024531451A (ja) * 2021-08-25 2024-08-29 インテグリス・インコーポレーテッド 剛性フレームバッグ
US20240382971A1 (en) * 2021-09-14 2024-11-21 Stellenbosch University Extraction device assembly
WO2024263523A1 (en) 2023-06-21 2024-12-26 Cepheid Real-time monitoring of liquid temperature
DE102024210965A1 (de) 2024-11-14 2026-05-21 Albert-Ludwigs-Universität Freiburg, Körperschaft des öffentlichen Rechts Verfahren und Vorrichtung zur Erzeugung von isolierten Flüssigkeitsteilvolumina

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5168038A (en) 1988-06-17 1992-12-01 The Board Of Trustees Of The Leland Stanford Junior University In situ transcription in cells and tissues
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
JPH03126208A (ja) 1989-10-11 1991-05-29 Nippon Chemicon Corp 電解コンデンサ用電解液
US5427930A (en) 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
SE9002579D0 (sv) * 1990-08-07 1990-08-07 Pharmacia Ab Method and apparatus for carrying out biochemical reactions
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
JP3080178B2 (ja) 1991-02-18 2000-08-21 東洋紡績株式会社 核酸配列の増幅方法およびそのための試薬キット
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
DE69739357D1 (de) 1996-06-04 2009-05-28 Univ Utah Res Found Überwachung der hybridisierung während pcr
GB9620934D0 (en) * 1996-10-08 1996-11-27 Molecular Drives Limited Multi-well containers
US6818185B1 (en) * 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US6403037B1 (en) * 2000-02-04 2002-06-11 Cepheid Reaction vessel and temperature control system
CA2311622A1 (en) * 2000-06-15 2001-12-15 Moussa Hoummady Sub-nanoliter liquid drop dispensing system and method therefor
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
JP4361271B2 (ja) 2000-10-10 2009-11-11 バイオトローブ・インコーポレイテツド アッセイ、合成、および保存用の器具、ならびに、その作製、使用、および操作の方法
US20080202927A1 (en) * 2000-11-03 2008-08-28 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US8277753B2 (en) 2002-08-23 2012-10-02 Life Technologies Corporation Microfluidic transfer pin
GB0321158D0 (en) * 2003-09-10 2003-10-08 Central Research Lab Ltd Apparatus and method for handling cells,embryos or oocytes
WO2005080606A1 (en) 2004-02-18 2005-09-01 Xiaochuan Zhou Fluidic devices and methods for multiplex chemical and biochemical reactions
US7414118B1 (en) 2004-04-14 2008-08-19 Applied Biosystems Inc. Modified oligonucleotides and applications thereof
MXPA06014185A (es) 2004-06-07 2007-04-16 Strides Arcolab Ltd Composicion farmaceutica que contiene una solucion estable y clara de medicamento anti-inflmatorio en capsulas de gelatina blanda, y proceso para producirlo.
US7473533B2 (en) 2004-12-30 2009-01-06 Corning Incorporated Membrane arrays and methods of manufacture
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
US7846716B2 (en) * 2005-04-28 2010-12-07 Fujifilm Corporation Microchip and analysis method using the same
WO2007002588A2 (en) * 2005-06-23 2007-01-04 Applera Corporation Thermal-cycling pipette tip
WO2007043619A1 (ja) * 2005-10-13 2007-04-19 Nissui Pharmaceutical Co., Ltd. 試験デバイス
EP1942877A4 (en) 2005-11-02 2011-09-14 Teikoku Pharma Usa Inc ORGANOLEPTICALLY ACCEPTABLE ORAL DOSAGE FORMS OF IBUPROFEN, MANUFACTURING METHOD AND APPLICATION
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
US8119352B2 (en) 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
US8187557B2 (en) 2006-07-13 2012-05-29 Cepheid Reagent reservoir system for analytical instruments
JP3126208U (ja) * 2006-08-04 2006-10-19 株式会社島津製作所 示差屈折率検出器及び液体クロマトグラフ。
US20080108122A1 (en) 2006-09-01 2008-05-08 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microchemical nanofactories
US20090093374A1 (en) * 2007-01-25 2009-04-09 Kahp-Yang Suh Method of arraying cells at single-cell level inside microfluidic channel and method of analysing cells using the same, and cell analysis chip used for carrying out the same
JP5494480B2 (ja) 2007-06-11 2014-05-14 和光純薬工業株式会社 集積リアルタイムce検出を用いるマイクロチップ大容量pcr
CN101896275A (zh) 2007-12-17 2010-11-24 龚海庆 微流控器件
NL1036865C2 (en) 2009-04-16 2010-10-19 Maxi Miliaan Bv Child vehicle seat.
JP5881936B2 (ja) * 2009-04-20 2016-03-09 ソニー株式会社 試料溶液導入キット及び試料溶液注入器
EP2826564B1 (en) * 2009-11-23 2018-12-26 3M Innovative Properties Company Microwell array articles and methods of use
DE102010041478A1 (de) 2010-09-27 2012-03-29 Zumtobel Lighting Gmbh Anordnung zur gerichteten Lichtabgabe
EP2441520A1 (en) 2010-10-12 2012-04-18 Eppendorf AG Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay
US8968684B2 (en) * 2011-04-28 2015-03-03 Bin Lian Microplates, reaction modules and detection systems
US9095852B2 (en) * 2011-08-22 2015-08-04 The Regents Of The University Of California Multilayer high density microwells
GB201118774D0 (en) * 2011-10-31 2011-12-14 British American Tobacco Co Fluid distribution in an exposure device
WO2013159116A1 (en) * 2012-04-20 2013-10-24 University Of Chicago Fluidic devices for biospecimen preservation
US9914968B2 (en) 2012-09-26 2018-03-13 Cepheid Honeycomb tube
US10850278B2 (en) * 2014-01-29 2020-12-01 Arizona Board Of Regents On Behalf Of Arizona State University Microreactor array platform
WO2015143442A2 (en) * 2014-03-21 2015-09-24 The Trustees Of Columbia University In The City Of New York Methods and devices for selection and isolation of aptamers
CA3029276C (en) * 2016-10-05 2023-03-07 Abbott Laboratories Devices and methods for sample analysis
WO2019098301A1 (ja) * 2017-11-17 2019-05-23 凸版印刷株式会社 標的分子の検出方法
EP3974844A4 (en) * 2019-05-21 2022-08-03 Toppan Inc. PROCEDURE FOR DETECTING A TARGET MOLECULE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12203135B2 (en) 2012-09-26 2025-01-21 Cepheid Honeycomb tube

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