JP6470286B2 - ラミニンの角膜内皮細胞培養への応用 - Google Patents

ラミニンの角膜内皮細胞培養への応用 Download PDF

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Publication number
JP6470286B2
JP6470286B2 JP2016535065A JP2016535065A JP6470286B2 JP 6470286 B2 JP6470286 B2 JP 6470286B2 JP 2016535065 A JP2016535065 A JP 2016535065A JP 2016535065 A JP2016535065 A JP 2016535065A JP 6470286 B2 JP6470286 B2 JP 6470286B2
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laminin
chain
corneal endothelial
seq
culture
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Japanese (ja)
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JP2016539641A (ja
JP2016539641A5 (cg-RX-API-DMAC7.html
Inventor
範子 小泉
範子 小泉
直毅 奥村
直毅 奥村
木下　茂
茂 木下
エー． クルーゼ フリードリッヒ
エー． クルーゼ フリードリッヒ
シュロッツァ−シュレハルト ウルズラ
シュロッツァ−シュレハルト ウルズラ
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KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
Senju Pharmaceutical Co Ltd
Doshisha Co Ltd
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KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
Senju Pharmaceutical Co Ltd
Doshisha Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2016535065A 2013-11-27 2014-11-26 ラミニンの角膜内皮細胞培養への応用 Active JP6470286B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013244972 2013-11-27
JP2013244972 2013-11-27
PCT/JP2014/081917 WO2015080297A1 (en) 2013-11-27 2014-11-26 Application of laminin to corneal endothelial cell culture

Related Child Applications (1)

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JP2019006098A Division JP2019054828A (ja) 2013-11-27 2019-01-17 ラミニンの角膜内皮細胞培養への応用

Publications (3)

Publication Number Publication Date
JP2016539641A JP2016539641A (ja) 2016-12-22
JP2016539641A5 JP2016539641A5 (cg-RX-API-DMAC7.html) 2017-12-07
JP6470286B2 true JP6470286B2 (ja) 2019-02-13

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JP2016535065A Active JP6470286B2 (ja) 2013-11-27 2014-11-26 ラミニンの角膜内皮細胞培養への応用
JP2019006098A Withdrawn JP2019054828A (ja) 2013-11-27 2019-01-17 ラミニンの角膜内皮細胞培養への応用
JP2020098407A Pending JP2020188778A (ja) 2013-11-27 2020-06-05 ラミニンの角膜内皮細胞培養への応用

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JP2019006098A Withdrawn JP2019054828A (ja) 2013-11-27 2019-01-17 ラミニンの角膜内皮細胞培養への応用
JP2020098407A Pending JP2020188778A (ja) 2013-11-27 2020-06-05 ラミニンの角膜内皮細胞培養への応用

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US (1) US11624053B2 (cg-RX-API-DMAC7.html)
EP (1) EP3074508B1 (cg-RX-API-DMAC7.html)
JP (3) JP6470286B2 (cg-RX-API-DMAC7.html)
CN (1) CN105814195A (cg-RX-API-DMAC7.html)
BR (1) BR112016011096A2 (cg-RX-API-DMAC7.html)
CA (1) CA2931280A1 (cg-RX-API-DMAC7.html)
ES (1) ES2763433T3 (cg-RX-API-DMAC7.html)
MX (1) MX2016006915A (cg-RX-API-DMAC7.html)
RU (1) RU2704984C1 (cg-RX-API-DMAC7.html)
WO (1) WO2015080297A1 (cg-RX-API-DMAC7.html)

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JP6849957B2 (ja) * 2015-11-10 2021-03-31 国立大学法人京都大学 ラミニンフラグメント含有培地を用いる細胞培養方法
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WO2019079809A1 (en) * 2017-10-22 2019-04-25 The Johns Hopkins University BIOMIMETIC PLATFORMS FOR MODELING VASCULAR PHYSIOPATHOLOGY, DIAGNOSIS AND THERAPY
WO2019102593A1 (ja) * 2017-11-24 2019-05-31 株式会社Ihi 細胞培養装置
JP6664755B1 (ja) * 2018-10-02 2020-03-13 学校法人同志社 角膜内皮細胞を保存するための方法および容器
US11445723B2 (en) 2018-10-02 2022-09-20 The Doshisha Method and container for preserving corneal endothelial cells
CN113557059A (zh) * 2019-03-12 2021-10-26 日产化学株式会社 角膜疾病治疗剂
JP2023025311A (ja) * 2020-02-05 2023-02-22 味の素株式会社 タンパク質の製造方法
CN112522179A (zh) * 2020-12-23 2021-03-19 江苏艾尔康生物医药科技有限公司 一种角膜内皮细胞的分离培养方法

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Also Published As

Publication number Publication date
EP3074508B1 (en) 2019-11-06
EP3074508A1 (en) 2016-10-05
MX2016006915A (es) 2017-01-23
WO2015080297A1 (en) 2015-06-04
CN105814195A (zh) 2016-07-27
US20170002318A1 (en) 2017-01-05
RU2704984C1 (ru) 2019-11-01
BR112016011096A2 (pt) 2017-09-19
CA2931280A1 (en) 2015-06-04
ES2763433T3 (es) 2020-05-28
JP2019054828A (ja) 2019-04-11
JP2020188778A (ja) 2020-11-26
JP2016539641A (ja) 2016-12-22
RU2016125225A (ru) 2018-01-09
US11624053B2 (en) 2023-04-11

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