JP6426696B2 - 呼吸器疾患の治療のための方法および製剤 - Google Patents
呼吸器疾患の治療のための方法および製剤 Download PDFInfo
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- JP6426696B2 JP6426696B2 JP2016502370A JP2016502370A JP6426696B2 JP 6426696 B2 JP6426696 B2 JP 6426696B2 JP 2016502370 A JP2016502370 A JP 2016502370A JP 2016502370 A JP2016502370 A JP 2016502370A JP 6426696 B2 JP6426696 B2 JP 6426696B2
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- 0 CCC([C@@](C)(*O*(N(*BN1NNC(C)C1)C1)=*)C1[C@@](C)*)O[N+]([C@](C)(*)C(*)(*)[C@](C)[C@](*(CC(C)C)(CC=C)OC)O*)[O-] Chemical compound CCC([C@@](C)(*O*(N(*BN1NNC(C)C1)C1)=*)C1[C@@](C)*)O[N+]([C@](C)(*)C(*)(*)[C@](C)[C@](*(CC(C)C)(CC=C)OC)O*)[O-] 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361781197P | 2013-03-14 | 2013-03-14 | |
| US61/781,197 | 2013-03-14 | ||
| PCT/US2014/027214 WO2014152326A1 (en) | 2013-03-14 | 2014-03-14 | Methods for treating respiratory diseases and formulations therefor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018200696A Division JP6810117B2 (ja) | 2013-03-14 | 2018-10-25 | 呼吸器疾患の治療のための方法および製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016513688A JP2016513688A (ja) | 2016-05-16 |
| JP2016513688A5 JP2016513688A5 (enExample) | 2017-04-13 |
| JP6426696B2 true JP6426696B2 (ja) | 2018-11-21 |
Family
ID=51581187
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502370A Active JP6426696B2 (ja) | 2013-03-14 | 2014-03-14 | 呼吸器疾患の治療のための方法および製剤 |
| JP2018200696A Active JP6810117B2 (ja) | 2013-03-14 | 2018-10-25 | 呼吸器疾患の治療のための方法および製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018200696A Active JP6810117B2 (ja) | 2013-03-14 | 2018-10-25 | 呼吸器疾患の治療のための方法および製剤 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9861616B2 (enExample) |
| EP (1) | EP2968801B1 (enExample) |
| JP (2) | JP6426696B2 (enExample) |
| CN (1) | CN105163785A (enExample) |
| AU (2) | AU2014239959A1 (enExample) |
| CA (1) | CA2905975A1 (enExample) |
| HK (1) | HK1217665A1 (enExample) |
| RU (1) | RU2015138796A (enExample) |
| WO (1) | WO2014152326A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601695B2 (en) | 2003-03-10 | 2009-10-13 | Optimer Pharmaceuticals, Inc. | Antibacterial agents |
| AU2008316830B2 (en) | 2007-10-25 | 2016-03-17 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| CN107854477A (zh) | 2008-10-24 | 2018-03-30 | 森普拉制药公司 | 使用含三唑的大环内酯治疗抗性疾病的方法 |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| US9480679B2 (en) | 2009-09-10 | 2016-11-01 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and MAC diseases |
| BR112012029586A2 (pt) | 2010-05-20 | 2016-08-02 | Cempra Pharmaceuticals Inc | processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos |
| KR20130120458A (ko) | 2010-09-10 | 2013-11-04 | 셈프라 파마슈티컬스, 인크. | 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드 |
| WO2013148891A1 (en) | 2012-03-27 | 2013-10-03 | Cempra Pharmaceuticals, Inc. | Parenteral formulations for administering macrolide antibiotics |
| WO2014152326A1 (en) * | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| AU2014233240B2 (en) | 2013-03-15 | 2018-08-09 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
| EP4095146A1 (en) | 2013-04-04 | 2022-11-30 | President And Fellows Of Harvard College | Macrolides and methods of their preparation and use |
| JP2017531663A (ja) | 2014-10-08 | 2017-10-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 14員ケトライドならびにそれらの調製および使用の方法 |
| PE20180219A1 (es) * | 2015-03-06 | 2018-01-31 | Cempra Pharmaceuticals Inc | Procesos para preparar fluorocetolidos |
| WO2016154591A1 (en) | 2015-03-25 | 2016-09-29 | President And Fellows Of Harvard College | Macrolides with modified desosamine sugars and uses thereof |
| US9659484B1 (en) * | 2015-11-02 | 2017-05-23 | Rapidsos, Inc. | Method and system for situational awareness for emergency response |
| CN106083695B (zh) * | 2016-06-21 | 2018-07-24 | 四川大学 | 一系列含薁不对称方酸菁小分子及制备方法和应用 |
| EP3409277A1 (en) * | 2017-05-30 | 2018-12-05 | Dompé farmaceutici s.p.a. | Il-8 inhibitors for use in the treatment and/or prevention of bacterial secondary infections |
| JP7868974B2 (ja) * | 2018-04-03 | 2026-06-02 | ノバフラックス インコーポレイテッド | 高吸収性ポリマーを備える洗浄組成物 |
| CN111826296B (zh) * | 2019-04-17 | 2022-06-17 | 深圳微健康基因科技有限公司 | 人葡萄球菌及其培养方法和应用 |
| CN110157773B (zh) * | 2019-06-05 | 2021-06-18 | 华中农业大学 | 鸡毒支原体对泰乐菌素的耐药判定标准试验方法 |
| EP4203926A4 (en) * | 2020-08-31 | 2024-10-09 | Insmed Incorporated | METHODS FOR TREATING NEWLY DIAGNOSED MYCOBACTERIUM AVIUM COMPLEX LUNG INFECTIONS |
| US20240226112A1 (en) * | 2021-04-29 | 2024-07-11 | Insmed Incorporated | Certain n-(1-cyano-2-phenylethyl)-1,4-oxazepane-2-carboxamides for treating cystic fibrosis |
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2014
- 2014-03-14 WO PCT/US2014/027214 patent/WO2014152326A1/en not_active Ceased
- 2014-03-14 CN CN201480024218.9A patent/CN105163785A/zh active Pending
- 2014-03-14 CA CA2905975A patent/CA2905975A1/en not_active Abandoned
- 2014-03-14 JP JP2016502370A patent/JP6426696B2/ja active Active
- 2014-03-14 HK HK16105618.3A patent/HK1217665A1/zh unknown
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| US9861616B2 (en) | 2018-01-09 |
| WO2014152326A1 (en) | 2014-09-25 |
| HK1220418A1 (en) | 2017-05-05 |
| CA2905975A1 (en) | 2014-09-25 |
| AU2014239959A1 (en) | 2015-10-01 |
| RU2015138796A3 (enExample) | 2018-03-20 |
| JP2019048826A (ja) | 2019-03-28 |
| EP2968801A4 (en) | 2016-09-07 |
| RU2015138796A (ru) | 2017-04-19 |
| CN105163785A (zh) | 2015-12-16 |
| JP6810117B2 (ja) | 2021-01-06 |
| JP2016513688A (ja) | 2016-05-16 |
| HK1217665A1 (zh) | 2017-01-20 |
| EP2968801A1 (en) | 2016-01-20 |
| EP2968801B1 (en) | 2018-09-26 |
| AU2018232990A1 (en) | 2018-10-11 |
| US20160030396A1 (en) | 2016-02-04 |
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