JP6412492B2 - ニコチン製剤 - Google Patents

ニコチン製剤 Download PDF

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Publication number
JP6412492B2
JP6412492B2 JP2015502199A JP2015502199A JP6412492B2 JP 6412492 B2 JP6412492 B2 JP 6412492B2 JP 2015502199 A JP2015502199 A JP 2015502199A JP 2015502199 A JP2015502199 A JP 2015502199A JP 6412492 B2 JP6412492 B2 JP 6412492B2
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JP
Japan
Prior art keywords
nicotine
film
solution
salt
content
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JP2015502199A
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English (en)
Japanese (ja)
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JP2015516948A (ja
Inventor
ヒュビネッテ，フレドリック
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ニコチーノ・アクチボラグ
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Publication of JP2015516948A publication Critical patent/JP2015516948A/ja
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    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
JP2015502199A 2012-03-27 2013-03-15 ニコチン製剤 Active JP6412492B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261615997P 2012-03-27 2012-03-27
US61/615,997 2012-03-27
EP12161483.8 2012-03-27
EP12161483 2012-03-27
PCT/EP2013/055456 WO2013143891A1 (en) 2012-03-27 2013-03-15 Nicotine formulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017151485A Division JP2017226686A (ja) 2012-03-27 2017-08-04 ニコチン製剤

Publications (2)

Publication Number Publication Date
JP2015516948A JP2015516948A (ja) 2015-06-18
JP6412492B2 true JP6412492B2 (ja) 2018-10-24

Family

ID=49258262

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015502199A Active JP6412492B2 (ja) 2012-03-27 2013-03-15 ニコチン製剤
JP2017151485A Pending JP2017226686A (ja) 2012-03-27 2017-08-04 ニコチン製剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017151485A Pending JP2017226686A (ja) 2012-03-27 2017-08-04 ニコチン製剤

Country Status (21)

Country Link
US (1) US20150096572A1 (cg-RX-API-DMAC10.html)
EP (1) EP2830589B1 (cg-RX-API-DMAC10.html)
JP (2) JP6412492B2 (cg-RX-API-DMAC10.html)
KR (1) KR102038342B1 (cg-RX-API-DMAC10.html)
CN (1) CN104411297B (cg-RX-API-DMAC10.html)
AU (1) AU2013242200B2 (cg-RX-API-DMAC10.html)
BR (1) BR112014023823B1 (cg-RX-API-DMAC10.html)
CA (1) CA2868445C (cg-RX-API-DMAC10.html)
IN (1) IN2014DN08879A (cg-RX-API-DMAC10.html)
MX (1) MX362918B (cg-RX-API-DMAC10.html)
MY (1) MY183216A (cg-RX-API-DMAC10.html)
NZ (1) NZ626974A (cg-RX-API-DMAC10.html)
PL (1) PL2830589T3 (cg-RX-API-DMAC10.html)
RS (1) RS58677B1 (cg-RX-API-DMAC10.html)
RU (1) RU2625836C2 (cg-RX-API-DMAC10.html)
SG (1) SG11201405958RA (cg-RX-API-DMAC10.html)
SI (1) SI2830589T1 (cg-RX-API-DMAC10.html)
SM (1) SMT201900220T1 (cg-RX-API-DMAC10.html)
UA (1) UA116440C2 (cg-RX-API-DMAC10.html)
WO (1) WO2013143891A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201407677B (cg-RX-API-DMAC10.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3166563T3 (da) * 2014-07-08 2021-02-15 Fertin Pharma As Oralt administrationssystem omfattende to rum
US11007144B2 (en) 2016-11-15 2021-05-18 Klaria Pharma Holding Ab Pharmaceutical formulation
EP3558267B1 (en) * 2016-12-20 2023-04-26 Fertin Pharma A/S A mucoadhesive oromucosal formulation comprising a nicotine complex
GB201808462D0 (en) * 2018-05-23 2018-07-11 Klaria Pharma Holding Ab Pharmaceutical formulation
GB201812499D0 (en) * 2018-07-31 2018-09-12 Nicoventures Holdings Ltd Method of making aerosol-forming substrate
WO2020136062A1 (en) * 2018-12-28 2020-07-02 Philip Morris Products S.A. Nicotine formulation comprising metal salt
WO2020141177A1 (en) * 2018-12-31 2020-07-09 Philip Morris Products S.A. Liquid nicotine formulation comprising water-immiscible solvents
GB201912505D0 (en) * 2019-08-30 2019-10-16 Klaria Pharma Holding Ab Pharmaceutical formulation
SE544672C2 (en) * 2020-05-07 2022-10-11 Liw Innovation Ab New compositions for oral or nasal use
WO2024037043A1 (zh) * 2023-04-28 2024-02-22 深圳华宝协同创新技术研究院有限公司 用于口腔粘膜的包含尼古丁的薄膜组合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86170A (en) 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
CA2178021C (en) * 1996-04-19 1999-09-28 Theodore H. Stanley Tobacco substitute
SE9900215D0 (sv) 1999-01-26 1999-01-26 Pharmacia & Upjohn Ab New use
JP5089840B2 (ja) * 2001-09-25 2012-12-05 救急薬品工業株式会社 ニコチン含有フィルム製剤
GB0508306D0 (en) * 2005-04-25 2005-06-01 Bioprogress Technology Ltd Nicotine dosage forms
SE530184C2 (sv) * 2005-12-23 2008-03-18 Kjell Stenberg Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20080286341A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
AU2008311350B2 (en) * 2007-10-11 2014-04-03 Philip Morris Products S.A. Smokeless tobacco product
KR20100095581A (ko) * 2007-12-11 2010-08-31 노파르티스 아게 다-영역 필름
PL2405942T3 (pl) * 2009-03-13 2018-04-30 Excellent Tech Products I Sverige Ab Produkt do podawania doustnego

Also Published As

Publication number Publication date
NZ626974A (en) 2016-09-30
AU2013242200B2 (en) 2017-03-02
SI2830589T1 (sl) 2019-06-28
BR112014023823A2 (cg-RX-API-DMAC10.html) 2017-06-20
EP2830589A1 (en) 2015-02-04
KR102038342B1 (ko) 2019-10-30
CA2868445A1 (en) 2013-10-03
BR112014023823B1 (pt) 2022-04-26
JP2017226686A (ja) 2017-12-28
CA2868445C (en) 2020-01-28
WO2013143891A1 (en) 2013-10-03
IN2014DN08879A (cg-RX-API-DMAC10.html) 2015-05-22
SMT201900220T1 (it) 2019-07-11
SG11201405958RA (en) 2014-10-30
MX2014010760A (es) 2015-03-20
RU2014143003A (ru) 2016-05-20
CN104411297A (zh) 2015-03-11
RU2625836C2 (ru) 2017-07-19
ZA201407677B (en) 2016-05-25
CN104411297B (zh) 2017-10-24
MY183216A (en) 2021-02-18
KR20140140021A (ko) 2014-12-08
HK1205679A1 (en) 2015-12-24
EP2830589B1 (en) 2019-02-13
AU2013242200A1 (en) 2014-10-16
PL2830589T3 (pl) 2019-07-31
JP2015516948A (ja) 2015-06-18
UA116440C2 (uk) 2018-03-26
US20150096572A1 (en) 2015-04-09
MX362918B (es) 2019-02-26
RS58677B1 (sr) 2019-06-28

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