UA116440C2 - Композиція нікотину - Google Patents
Композиція нікотинуInfo
- Publication number
- UA116440C2 UA116440C2 UAA201407757A UAA201407757A UA116440C2 UA 116440 C2 UA116440 C2 UA 116440C2 UA A201407757 A UAA201407757 A UA A201407757A UA A201407757 A UAA201407757 A UA A201407757A UA 116440 C2 UA116440 C2 UA 116440C2
- Authority
- UA
- Ukraine
- Prior art keywords
- film
- nicotine
- solution
- mean
- weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Addiction (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Спосіб одержання мукоадгезивної плівки, що містить нікотин, шляхом одержання водного розчину при рН від 9,5 до 13, до складу якого входить (І) нікотинова сіль, (II) лужний рН-регулюючий агент і (III) плівкоутворювальний агент, який містить альгінатну сіль одновалентного катіона або суміш альгінатних солей одновалентних катіонів; плівкоутворювальний агент, що має середній вміст гулуронату (G) від 50 до 85 % за масою, середній вміст мануронату (М) від 15 до 50 % за масою, середню молекулярну масу від 30000 г/моль до 90000 г/моль і такі властивості, що 10 % водний розчин його за температури 20 °C має в'язкість 100-1000 мПас, що було виміряно за швидкості зсуву 20 об./хв. шляхом використання віскозиметра Брукфільда зі шпинделем № 2; нанесення розчину на тверду поверхню; і утримування розчину на зазначеній поверхні до висихання.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261615997P | 2012-03-27 | 2012-03-27 | |
| EP12161483 | 2012-03-27 | ||
| PCT/EP2013/055456 WO2013143891A1 (en) | 2012-03-27 | 2013-03-15 | Nicotine formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA116440C2 true UA116440C2 (uk) | 2018-03-26 |
Family
ID=49258262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201407757A UA116440C2 (uk) | 2012-03-27 | 2013-03-15 | Композиція нікотину |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20150096572A1 (uk) |
| EP (1) | EP2830589B1 (uk) |
| JP (2) | JP6412492B2 (uk) |
| KR (1) | KR102038342B1 (uk) |
| CN (1) | CN104411297B (uk) |
| AU (1) | AU2013242200B2 (uk) |
| BR (1) | BR112014023823B1 (uk) |
| CA (1) | CA2868445C (uk) |
| HK (1) | HK1205679A1 (uk) |
| IN (1) | IN2014DN08879A (uk) |
| MX (1) | MX362918B (uk) |
| MY (1) | MY183216A (uk) |
| NZ (1) | NZ626974A (uk) |
| PL (1) | PL2830589T3 (uk) |
| RS (1) | RS58677B1 (uk) |
| RU (1) | RU2625836C2 (uk) |
| SG (1) | SG11201405958RA (uk) |
| SI (1) | SI2830589T1 (uk) |
| UA (1) | UA116440C2 (uk) |
| WO (1) | WO2013143891A1 (uk) |
| ZA (1) | ZA201407677B (uk) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170172938A1 (en) * | 2014-07-08 | 2017-06-22 | Fertin Pharma A/S | Oral delivery system comprising two compartments |
| EP3558267B1 (en) * | 2016-12-20 | 2023-04-26 | Fertin Pharma A/S | A mucoadhesive oromucosal formulation comprising a nicotine complex |
| KR20210107690A (ko) * | 2018-12-28 | 2021-09-01 | 필립모리스 프로덕츠 에스.에이. | 금속염을 포함하는 니코틴 제형 |
| CN113242696B (zh) * | 2018-12-31 | 2023-04-28 | 菲利普莫里斯生产公司 | 液体尼古丁制剂 |
| SE544672C2 (en) * | 2020-05-07 | 2022-10-11 | Liw Innovation Ab | New compositions for oral or nasal use |
| WO2024037043A1 (zh) * | 2023-04-28 | 2024-02-22 | 深圳华宝协同创新技术研究院有限公司 | 用于口腔粘膜的包含尼古丁的薄膜组合物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL86170A (en) | 1987-05-01 | 1992-12-01 | Elan Transdermal Ltd | Preparations and compositions comprising nicotine for percutaneous administration |
| CA2178021C (en) * | 1996-04-19 | 1999-09-28 | Theodore H. Stanley | Tobacco substitute |
| SE9900215D0 (sv) | 1999-01-26 | 1999-01-26 | Pharmacia & Upjohn Ab | New use |
| JP5089840B2 (ja) * | 2001-09-25 | 2012-12-05 | 救急薬品工業株式会社 | ニコチン含有フィルム製剤 |
| GB0508306D0 (en) * | 2005-04-25 | 2005-06-01 | Bioprogress Technology Ltd | Nicotine dosage forms |
| SE530184C2 (sv) * | 2005-12-23 | 2008-03-18 | Kjell Stenberg | Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater |
| US20080286340A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered nicotine containing products |
| US20080286341A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered coated nicotine containing products |
| EA021392B1 (ru) * | 2007-10-11 | 2015-06-30 | Филип Моррис Продактс С.А. | Бездымный табачный продукт |
| CN101896172A (zh) * | 2007-12-11 | 2010-11-24 | 诺瓦提斯公司 | 多区膜 |
| EP2405942B1 (en) * | 2009-03-13 | 2017-11-01 | Excellent Tech Products i Sverige AB | Oral delivery product |
-
2013
- 2013-03-15 CN CN201380017041.5A patent/CN104411297B/zh active Active
- 2013-03-15 SI SI201331410T patent/SI2830589T1/sl unknown
- 2013-03-15 RU RU2014143003A patent/RU2625836C2/ru active
- 2013-03-15 KR KR1020147023909A patent/KR102038342B1/ko active IP Right Grant
- 2013-03-15 MY MYPI2014002725A patent/MY183216A/en unknown
- 2013-03-15 AU AU2013242200A patent/AU2013242200B2/en active Active
- 2013-03-15 NZ NZ626974A patent/NZ626974A/en unknown
- 2013-03-15 BR BR112014023823-5A patent/BR112014023823B1/pt active IP Right Grant
- 2013-03-15 US US14/386,083 patent/US20150096572A1/en not_active Abandoned
- 2013-03-15 CA CA2868445A patent/CA2868445C/en active Active
- 2013-03-15 RS RS20190478A patent/RS58677B1/sr unknown
- 2013-03-15 EP EP13712730.4A patent/EP2830589B1/en active Active
- 2013-03-15 UA UAA201407757A patent/UA116440C2/uk unknown
- 2013-03-15 MX MX2014010760A patent/MX362918B/es active IP Right Grant
- 2013-03-15 PL PL13712730T patent/PL2830589T3/pl unknown
- 2013-03-15 JP JP2015502199A patent/JP6412492B2/ja active Active
- 2013-03-15 WO PCT/EP2013/055456 patent/WO2013143891A1/en active Application Filing
- 2013-03-15 SG SG11201405958RA patent/SG11201405958RA/en unknown
-
2014
- 2014-10-22 IN IN8879DEN2014 patent/IN2014DN08879A/en unknown
- 2014-10-22 ZA ZA2014/07677A patent/ZA201407677B/en unknown
-
2015
- 2015-06-30 HK HK15106184.6A patent/HK1205679A1/xx unknown
-
2017
- 2017-08-04 JP JP2017151485A patent/JP2017226686A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2014010760A (es) | 2015-03-20 |
| KR102038342B1 (ko) | 2019-10-30 |
| RU2014143003A (ru) | 2016-05-20 |
| EP2830589A1 (en) | 2015-02-04 |
| IN2014DN08879A (uk) | 2015-05-22 |
| NZ626974A (en) | 2016-09-30 |
| US20150096572A1 (en) | 2015-04-09 |
| HK1205679A1 (en) | 2015-12-24 |
| SG11201405958RA (en) | 2014-10-30 |
| ZA201407677B (en) | 2016-05-25 |
| KR20140140021A (ko) | 2014-12-08 |
| CA2868445A1 (en) | 2013-10-03 |
| WO2013143891A1 (en) | 2013-10-03 |
| CN104411297B (zh) | 2017-10-24 |
| SI2830589T1 (sl) | 2019-06-28 |
| JP2015516948A (ja) | 2015-06-18 |
| MX362918B (es) | 2019-02-26 |
| JP6412492B2 (ja) | 2018-10-24 |
| JP2017226686A (ja) | 2017-12-28 |
| BR112014023823A2 (uk) | 2017-06-20 |
| PL2830589T3 (pl) | 2019-07-31 |
| RU2625836C2 (ru) | 2017-07-19 |
| MY183216A (en) | 2021-02-18 |
| AU2013242200B2 (en) | 2017-03-02 |
| CA2868445C (en) | 2020-01-28 |
| RS58677B1 (sr) | 2019-06-28 |
| CN104411297A (zh) | 2015-03-11 |
| EP2830589B1 (en) | 2019-02-13 |
| BR112014023823B1 (pt) | 2022-04-26 |
| AU2013242200A1 (en) | 2014-10-16 |
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