JP6401297B2 - インスリン分泌能分析装置、当該装置を備えるインスリン分泌能分析システム及びインスリン分泌能分析方法 - Google Patents
インスリン分泌能分析装置、当該装置を備えるインスリン分泌能分析システム及びインスリン分泌能分析方法 Download PDFInfo
- Publication number
- JP6401297B2 JP6401297B2 JP2016565750A JP2016565750A JP6401297B2 JP 6401297 B2 JP6401297 B2 JP 6401297B2 JP 2016565750 A JP2016565750 A JP 2016565750A JP 2016565750 A JP2016565750 A JP 2016565750A JP 6401297 B2 JP6401297 B2 JP 6401297B2
- Authority
- JP
- Japan
- Prior art keywords
- insulin secretion
- hba1c
- value
- blood glucose
- fasting blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7282—Event detection, e.g. detecting unique waveforms indicative of a medical condition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
Description
102 入力部
103 出力部
104 CPU
105 メモリ
106 記憶媒体
107 関係式作成部
108 インスリン分泌能評価式作成部
109 推定HbA1c算出部
110 インスリン分泌能評価値算出部
111 指導対象者選定部
120 データベース
121 健診情報記録部
122 関係式記憶部
123 評価式記憶部
124 指導対象者記憶部
Claims (7)
- 少なくとも、分析対象者の空腹時血糖値とHbA1c値とを入力する入力部と、
複数の被検査者に関する空腹時血糖値とHbA1c値とを含むデータセットに含まれるHbA1c値を目的変数とし、同データに含まれる空腹時血糖値を説明変数として回帰分析を行うことにより得られた関係式に、上記入力部で入力した空腹時血糖値を代入して推定HbA1c値を算出する推定HbA1c算出部と、
入力したHbA1c値と推定HbA1c値との差分値を計算する評価式に前記入力部で入力したHbA1c値と前記推定HbA1c算出部で算出した推定HbA1c値とを代入して得られるインスリン分泌能評価値を算出するインスリン分泌能評価値算出部と
を備えるインスリン分泌能分析装置。 - 前記インスリン分泌能評価値算出部で算出したインスリン分泌能評価値と基準値とを比較してインスリン分泌能に関する情報を出力する出力部を更に有することを特徴とする請求項1記載のインスリン分泌能分析装置。
- 前記入力部で入力した体重情報と、前記インスリン分泌能評価値算出部で算出したインスリン分泌能評価値とから、糖尿病に関する指導要否を判定する指導要否判定部を更に有することを特徴とする請求項1記載のインスリン分泌能分析装置。
- 複数の被検査者に関する空腹時血糖値とHbA1c値とを含むデータセットを格納した健診データ記憶部と、前記入力部で入力した体重情報と、前記インスリン分泌能評価値算出部で算出したインスリン分泌能評価値とから、前記健診データ記憶部に格納されたデータセットのなかから、糖尿病に関する指導対象者を選定する指導対象者選定部とを更に有することを特徴とする請求項1記載のインスリン分泌能分析装置。
- 請求項1乃至4いずれか一項記載のインスリン分泌能分析装置と、
分析対象者に関する少なくとも空腹時血糖値とHbA1c値とを含むデータセットを有する端末と、
を備え、前記端末から分析対象者に関する前記データセットを前記インスリン分泌能分析装置に入力し、前記インスリン分泌能分析装置にて分析対象者に関するインスリン分泌能を分析することを特徴とするインスリン分泌能分析システム。 - 前記端末は、分析対象者に関する空腹時血糖値を測定する及び/又はHbA1c値を測定する測定器であることを特徴とする請求項5記載のインスリン分泌能分析システム。
- 少なくとも、分析対象者の空腹時血糖値とHbA1c値とを入力する工程と、
複数の被検査者に関する空腹時血糖値とHbA1c値とを含むデータセットに含まれるHbA1c値を目的変数とし、同データに含まれる空腹時血糖値を説明変数として回帰分析を行うことにより得られた関係式に、前記工程で入力した空腹時血糖値を代入して推定HbA1c値を算出する工程と、
入力したHbA1c値と推定HbA1c値との差分値を計算する評価式に前記工程で入力したHbA1c値と前記工程で算出した推定HbA1c値とを代入して得られるインスリン分泌能評価値を算出する工程と
を備えるインスリン分泌能分析方法。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2014/084285 WO2016103390A1 (ja) | 2014-12-25 | 2014-12-25 | インスリン分泌能分析装置、当該装置を備えるインスリン分泌能分析システム及びインスリン分泌能分析方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2016103390A1 JPWO2016103390A1 (ja) | 2017-06-29 |
JP6401297B2 true JP6401297B2 (ja) | 2018-10-10 |
Family
ID=56149486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016565750A Active JP6401297B2 (ja) | 2014-12-25 | 2014-12-25 | インスリン分泌能分析装置、当該装置を備えるインスリン分泌能分析システム及びインスリン分泌能分析方法 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20170316176A1 (ja) |
JP (1) | JP6401297B2 (ja) |
CN (1) | CN107003315B (ja) |
WO (1) | WO2016103390A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20210154281A (ko) * | 2020-06-11 | 2021-12-21 | 고려대학교 산학협력단 | 췌장 인슐린 분비능 평가 지표 제공 방법 및 장치 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10925547B2 (en) * | 2017-01-16 | 2021-02-23 | Bionime Corporation | System for monitoring physiological condition |
JP7282298B2 (ja) * | 2019-07-31 | 2023-05-29 | アークレイ株式会社 | 推定方法及び平均血糖値推定システム |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI112545B (fi) * | 1997-05-30 | 2003-12-15 | Nokia Corp | Menetelmä ja järjestelmä potilaan veren glykosyloidun hemoglobiinikomponentin tason ennustamiseksi |
EP1253942A4 (en) * | 2000-02-01 | 2004-06-16 | Tanox Inc | CD40-BINDING AND APC-ACTIVATING MOLECULES |
ATE396277T1 (de) * | 2002-03-29 | 2008-06-15 | Asahi Kasei Pharma Corp | Verfahren zum nachweis einer milden beeinträchtigten glukosetoleranz oder insulin- hyposekretion |
US8538703B2 (en) * | 2002-08-13 | 2013-09-17 | University Of Virginia Patent Foundation | Method, system, and computer program product for the processing of self-monitoring blood glucose(SMBG)data to enhance diabetic self-management |
CN101079082A (zh) * | 2002-08-13 | 2007-11-28 | 弗吉尼亚大学专利基金会 | 用于处理自我监测血糖(smbg)数据从而提高糖尿病患者自我管理的方法、系统和计算机程序产品 |
JP2006304833A (ja) * | 2005-04-26 | 2006-11-09 | Sysmex Corp | 診断支援システム及びコンピュータプログラム |
US7824333B2 (en) * | 2006-03-31 | 2010-11-02 | Lifescan, Inc. | Diabetes management methods and systems |
US9429579B2 (en) * | 2006-09-22 | 2016-08-30 | Arkray, Inc. | Blood analysis apparatus |
EP1980851A3 (en) * | 2007-03-30 | 2014-03-12 | Tanita Corporation | Blood sugar condition estimation method and apparatus |
CN101275953A (zh) * | 2007-03-30 | 2008-10-01 | 株式会社百利达 | 血糖状态推定方法以及装置 |
BRPI0813708A2 (pt) * | 2007-07-09 | 2014-12-30 | Univ Virginia Patent Found | Método, sistema e produto de programa de computador para avaliação de sensibilidade a insulina, coeficiente de insulina / carboidrato, e fatores de correção de insulina em diabetes a partir de dados de auto-monitoramento |
BRPI0815095B1 (pt) * | 2007-07-17 | 2021-04-13 | Metabolon, Inc | Método de classificação de um indivíduo de acordo com a tolerância à glicose predita em tolerância à glicose normal (ngt), tolerância à glicose de jejum prejudicada (ifg), ou tolerância à glicose prejudicada (igt), para diabetes tipo 2, método de determinação da suscetibilidade de um indivíduo a diabetes tipo 2 e método de monitoramento da progressão ou regressão do pré- diabetes em um indivíduo |
CN102177434B (zh) * | 2008-08-08 | 2014-04-02 | 乔治亚大学研究基金公司 | 用于预测能够分泌至体液中的蛋白质的方法及系统 |
US20120253840A1 (en) * | 2009-12-21 | 2012-10-04 | Stc.Unm | System and methods for estimating hba1c, treatment response, and hypoglycemia risk using self-monitoring of blood glucose data |
JP2013534925A (ja) * | 2010-06-25 | 2013-09-09 | グラクソ グループ リミテッド | 免疫関連疾患患者の治療方法 |
JP5900044B2 (ja) * | 2012-03-12 | 2016-04-06 | オムロンヘルスケア株式会社 | 糖尿病治療支援装置、糖尿病治療支援方法、糖尿病治療支援プログラム |
US20130316375A1 (en) * | 2012-05-24 | 2013-11-28 | Orban Biotech Llc | Diabetes biomarkers |
WO2013188605A2 (en) * | 2012-06-15 | 2013-12-19 | Nuclea Biotechnologies, Inc. | Predictive markers for cancer and metabolic syndrome |
US20140324460A1 (en) * | 2012-09-26 | 2014-10-30 | Health Diagnostic Laboratory, Inc. | Method for determining and managing total cardiodiabetes risk |
-
2014
- 2014-12-25 JP JP2016565750A patent/JP6401297B2/ja active Active
- 2014-12-25 US US15/517,642 patent/US20170316176A1/en not_active Abandoned
- 2014-12-25 WO PCT/JP2014/084285 patent/WO2016103390A1/ja active Application Filing
- 2014-12-25 CN CN201480083933.XA patent/CN107003315B/zh active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20210154281A (ko) * | 2020-06-11 | 2021-12-21 | 고려대학교 산학협력단 | 췌장 인슐린 분비능 평가 지표 제공 방법 및 장치 |
KR102492194B1 (ko) | 2020-06-11 | 2023-01-27 | 고려대학교 산학협력단 | 췌장 인슐린 분비능 평가 지표 제공 방법 및 장치 |
Also Published As
Publication number | Publication date |
---|---|
US20170316176A1 (en) | 2017-11-02 |
CN107003315A (zh) | 2017-08-01 |
WO2016103390A1 (ja) | 2016-06-30 |
CN107003315B (zh) | 2018-09-25 |
JPWO2016103390A1 (ja) | 2017-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Wiley et al. | A metabolic syndrome severity score: A tool to quantify cardio-metabolic risk factors | |
Timar et al. | The impact of diabetic neuropathy on balance and on the risk of falls in patients with type 2 diabetes mellitus: a cross-sectional study | |
Mei et al. | Frailty as a predictor of negative health outcomes in chronic kidney disease: a systematic review and meta-analysis | |
Di Chiara et al. | Education and hypertension: impact on global cardiovascular risk | |
CN104737014B (zh) | 测量和使用生物样品的氧化还原电位的方法和系统 | |
Santin et al. | Performance of subjective global assessment and malnutrition inflammation score for monitoring the nutritional status of older adults on hemodialysis | |
Ma et al. | Blood pressure variation and subclinical brain disease | |
Cicone et al. | Age-based prediction of maximal heart rate in children and adolescents: A systematic review and meta-analysis | |
Takahashi et al. | Comparison between oscillometric-and Doppler-ABI in elderly individuals | |
Yavuz et al. | Identifying uncontrolled asthma in children with the childhood asthma control test or exhaled nitric oxide measurement | |
Haun et al. | Waist-height ratio compared to other indicators of obesity as predictosr of high coronary risk | |
Liff et al. | Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity | |
JP6401297B2 (ja) | インスリン分泌能分析装置、当該装置を備えるインスリン分泌能分析システム及びインスリン分泌能分析方法 | |
Coutts et al. | Psychotic disorders as a framework for precision psychiatry | |
Dallaire-Théroux et al. | Evaluation of intensive vs standard blood pressure reduction and association with cognitive decline and dementia: a systematic review and meta-analysis | |
Ünlü et al. | Impact of statin use on high sensitive troponin T levels with moderate exercise | |
Holdom et al. | Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with amyotrophic lateral sclerosis | |
US20070161868A1 (en) | Method and system for determining whether additional laboratory tests will yield values beyond a threshold level | |
Winkler et al. | Patient-and clinician-reported outcome in eating disorders | |
Downs | Functional assessment of chronic obstructive pulmonary disease | |
Vianna et al. | Accuracy and adequacy of waist circumference cut-off points currently recommended in Brazilian adults | |
JP5811545B2 (ja) | 疲労のバイオマーカーおよびその利用 | |
Barbosa-Leiker et al. | Longitudinal measurement invariance of the metabolic syndrome: is the assessment of the metabolic syndrome stable over time? | |
Labrecque et al. | Functional clinical impairments and frailty in interstitial lung disease patients | |
Sushmitha et al. | Exploring the relationship between the indices of body composition with grip strength performance and peak VO2 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20170308 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180206 |
|
A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180402 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180814 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180906 |
|
R151 | Written notification of patent or utility model registration |
Ref document number: 6401297 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R151 |