JP6399410B2 - 幹細胞の治療可能性を高めるための組成物および方法 - Google Patents
幹細胞の治療可能性を高めるための組成物および方法 Download PDFInfo
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- JP6399410B2 JP6399410B2 JP2015562410A JP2015562410A JP6399410B2 JP 6399410 B2 JP6399410 B2 JP 6399410B2 JP 2015562410 A JP2015562410 A JP 2015562410A JP 2015562410 A JP2015562410 A JP 2015562410A JP 6399410 B2 JP6399410 B2 JP 6399410B2
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/31—Combination therapy
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- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13159548.0 | 2013-03-15 | ||
| EP13159548.0A EP2777703B1 (en) | 2013-03-15 | 2013-03-15 | Compositions and methods for enhancing the therapeutic potential of stem cells |
| PCT/IB2014/001248 WO2014140930A2 (en) | 2013-03-15 | 2014-03-13 | Compostions and methods for enhancing the therapeutic potential of stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016510808A JP2016510808A (ja) | 2016-04-11 |
| JP2016510808A5 JP2016510808A5 (enExample) | 2017-04-13 |
| JP6399410B2 true JP6399410B2 (ja) | 2018-10-03 |
Family
ID=47900872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562410A Active JP6399410B2 (ja) | 2013-03-15 | 2014-03-13 | 幹細胞の治療可能性を高めるための組成物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20160030482A1 (enExample) |
| EP (1) | EP2777703B1 (enExample) |
| JP (1) | JP6399410B2 (enExample) |
| KR (1) | KR102203925B1 (enExample) |
| CN (1) | CN105050597A (enExample) |
| AU (1) | AU2014229502B2 (enExample) |
| BR (1) | BR112015022565A2 (enExample) |
| CA (1) | CA2905650C (enExample) |
| ES (1) | ES2602078T3 (enExample) |
| WO (1) | WO2014140930A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019144967A1 (zh) * | 2018-01-29 | 2019-08-01 | 中国科学院动物研究所 | 一种破坏细胞机械稳态以及促进组织器官的再生修复的方法及其应用 |
| HU231285B1 (hu) | 2018-04-18 | 2022-08-28 | Printnet Kereskedelmi És Szolgáltató Kft. | A miozin-2-izoformákat szelektíven gátló, gyógyászatilag hatásos vegyületek |
| CN108728410B (zh) * | 2018-06-19 | 2020-04-21 | 中国医学科学院阜外医院 | 基于药物预处理的间充质干细胞来源外泌体的制备方法 |
| JP7230409B2 (ja) * | 2018-10-02 | 2023-03-01 | カシオ計算機株式会社 | 判定装置、判定方法及び判定プログラム |
| JP7618570B2 (ja) | 2019-03-08 | 2025-01-21 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション | 植物細胞におけるニトロゲナーゼポリペプチドの発現 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008011176A2 (en) | 2006-07-21 | 2008-01-24 | Northwestern University | Myosin light chain kinase inhibitor compounds, compositions and related methods of use |
| CN101125146B (zh) * | 2007-07-02 | 2011-05-04 | 中国药科大学 | 一种防治炎症相关心脑血管疾病的药物靶标及其抑制剂 |
| AU2009208391A1 (en) * | 2008-01-31 | 2009-08-06 | Monash University | Methods of treating thromboembolic disorders |
| CA2753208C (en) | 2009-02-20 | 2018-08-21 | Cellular Dynamics International, Inc. | Methods and compositions for the differentiation of stem cells |
| WO2010120785A2 (en) * | 2009-04-13 | 2010-10-21 | The Regents Of The University Of California | Methods and compositions for stem cell cultures |
| JP2013541344A (ja) | 2010-11-09 | 2013-11-14 | ロンザ ケルン ゲーエムベーハー | 支持体への細胞の結合を調節するための方法 |
| CN102940631B (zh) * | 2012-11-02 | 2015-04-15 | 清华大学 | Blebbistatin在促进干细胞存活和维持干细胞干性中的应用 |
-
2013
- 2013-03-15 EP EP13159548.0A patent/EP2777703B1/en active Active
- 2013-03-15 ES ES13159548.0T patent/ES2602078T3/es active Active
-
2014
- 2014-03-13 CN CN201480015952.9A patent/CN105050597A/zh active Pending
- 2014-03-13 US US14/777,352 patent/US20160030482A1/en not_active Abandoned
- 2014-03-13 WO PCT/IB2014/001248 patent/WO2014140930A2/en not_active Ceased
- 2014-03-13 JP JP2015562410A patent/JP6399410B2/ja active Active
- 2014-03-13 AU AU2014229502A patent/AU2014229502B2/en active Active
- 2014-03-13 BR BR112015022565A patent/BR112015022565A2/pt not_active Application Discontinuation
- 2014-03-13 CA CA2905650A patent/CA2905650C/en active Active
- 2014-03-13 KR KR1020157029741A patent/KR102203925B1/ko active Active
-
2017
- 2017-08-28 US US15/688,148 patent/US20180055888A1/en not_active Abandoned
-
2020
- 2020-01-09 US US16/738,495 patent/US20200147142A1/en not_active Abandoned
-
2024
- 2024-06-05 US US18/734,900 patent/US20240316111A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN105050597A (zh) | 2015-11-11 |
| US20240316111A1 (en) | 2024-09-26 |
| AU2014229502A1 (en) | 2015-09-24 |
| BR112015022565A2 (pt) | 2017-07-18 |
| KR20150131324A (ko) | 2015-11-24 |
| CA2905650C (en) | 2022-08-23 |
| US20180055888A1 (en) | 2018-03-01 |
| WO2014140930A3 (en) | 2014-12-24 |
| US20160030482A1 (en) | 2016-02-04 |
| AU2014229502A9 (en) | 2016-06-16 |
| US20200147142A1 (en) | 2020-05-14 |
| ES2602078T3 (es) | 2017-02-17 |
| JP2016510808A (ja) | 2016-04-11 |
| AU2014229502B2 (en) | 2019-03-14 |
| WO2014140930A9 (en) | 2016-01-14 |
| WO2014140930A2 (en) | 2014-09-18 |
| CA2905650A1 (en) | 2014-09-18 |
| EP2777703B1 (en) | 2016-09-14 |
| KR102203925B1 (ko) | 2021-01-19 |
| EP2777703A1 (en) | 2014-09-17 |
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