CA2905650C - Compostions and methods for enhancing the therapeutic potential of stem cells - Google Patents
Compostions and methods for enhancing the therapeutic potential of stem cells Download PDFInfo
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2320/00—Applications; Uses
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Applications Claiming Priority (3)
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| EP13159548.0 | 2013-03-15 | ||
| EP13159548.0A EP2777703B1 (en) | 2013-03-15 | 2013-03-15 | Compositions and methods for enhancing the therapeutic potential of stem cells |
| PCT/IB2014/001248 WO2014140930A2 (en) | 2013-03-15 | 2014-03-13 | Compostions and methods for enhancing the therapeutic potential of stem cells |
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| CA2905650A1 CA2905650A1 (en) | 2014-09-18 |
| CA2905650C true CA2905650C (en) | 2022-08-23 |
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| CA2905650A Active CA2905650C (en) | 2013-03-15 | 2014-03-13 | Compostions and methods for enhancing the therapeutic potential of stem cells |
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| ES (1) | ES2602078T3 (enExample) |
| WO (1) | WO2014140930A2 (enExample) |
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| WO2019144967A1 (zh) | 2018-01-29 | 2019-08-01 | 中国科学院动物研究所 | 一种破坏细胞机械稳态以及促进组织器官的再生修复的方法及其应用 |
| HU231285B1 (hu) | 2018-04-18 | 2022-08-28 | Printnet Kereskedelmi És Szolgáltató Kft. | A miozin-2-izoformákat szelektíven gátló, gyógyászatilag hatásos vegyületek |
| CN108728410B (zh) * | 2018-06-19 | 2020-04-21 | 中国医学科学院阜外医院 | 基于药物预处理的间充质干细胞来源外泌体的制备方法 |
| JP7230409B2 (ja) * | 2018-10-02 | 2023-03-01 | カシオ計算機株式会社 | 判定装置、判定方法及び判定プログラム |
| BR112021017799A2 (pt) | 2019-03-08 | 2021-11-23 | Commw Scient Ind Res Org | Célula vegetal, planta ou uma parte da mesma, polipeptídeo de fusão nifd ou produto clivado do mesmo, combinação do polipeptídeo de fusão nifd ou produto clivado do mesmo e um polipeptídeo de fusão nifd que compreende um mtp fundido translacionalmente para um polipeptídeo de nifk (nk) ou um produto clivado de mpp do mesmo, polinucleotídeo, vetor, uso de um polinucleotídeo, método de produção uma planta transgênica, método de produção de semente transgênica, método de produção de farinha, farinha integral, amido, óleo, farinha de sementes ou outro produto obtido a partir de sementes, produto produzido a partir da planta transgênica ou parte da mesma, método de preparação de um produto alimentício, e processo de alimentação de um animal |
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| WO2008011176A2 (en) | 2006-07-21 | 2008-01-24 | Northwestern University | Myosin light chain kinase inhibitor compounds, compositions and related methods of use |
| CN101125146B (zh) * | 2007-07-02 | 2011-05-04 | 中国药科大学 | 一种防治炎症相关心脑血管疾病的药物靶标及其抑制剂 |
| AU2009208391A1 (en) * | 2008-01-31 | 2009-08-06 | Monash University | Methods of treating thromboembolic disorders |
| US8557580B2 (en) | 2009-02-20 | 2013-10-15 | Cellular Dynamics International, Inc. | Methods and compositions for the differentiation of stem cells |
| CN102395672A (zh) * | 2009-04-13 | 2012-03-28 | 加利福尼亚大学董事会 | 用于干细胞培养的方法和组合物 |
| CN103201377A (zh) | 2010-11-09 | 2013-07-10 | 隆萨科隆有限公司 | 控制细胞与基质结合的方法 |
| CN102940631B (zh) * | 2012-11-02 | 2015-04-15 | 清华大学 | Blebbistatin在促进干细胞存活和维持干细胞干性中的应用 |
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2013
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- 2014-03-13 US US14/777,352 patent/US20160030482A1/en not_active Abandoned
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- 2014-03-13 BR BR112015022565A patent/BR112015022565A2/pt not_active Application Discontinuation
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2017
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2020
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2024
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Also Published As
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| US20180055888A1 (en) | 2018-03-01 |
| AU2014229502B2 (en) | 2019-03-14 |
| WO2014140930A9 (en) | 2016-01-14 |
| WO2014140930A3 (en) | 2014-12-24 |
| CA2905650A1 (en) | 2014-09-18 |
| BR112015022565A2 (pt) | 2017-07-18 |
| US20160030482A1 (en) | 2016-02-04 |
| ES2602078T3 (es) | 2017-02-17 |
| JP6399410B2 (ja) | 2018-10-03 |
| JP2016510808A (ja) | 2016-04-11 |
| KR102203925B1 (ko) | 2021-01-19 |
| US20200147142A1 (en) | 2020-05-14 |
| CN105050597A (zh) | 2015-11-11 |
| EP2777703A1 (en) | 2014-09-17 |
| WO2014140930A2 (en) | 2014-09-18 |
| AU2014229502A9 (en) | 2016-06-16 |
| EP2777703B1 (en) | 2016-09-14 |
| AU2014229502A1 (en) | 2015-09-24 |
| KR20150131324A (ko) | 2015-11-24 |
| US20240316111A1 (en) | 2024-09-26 |
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