JP6347743B2 - コクリエート組成物およびその製造および使用方法 - Google Patents

コクリエート組成物およびその製造および使用方法 Download PDF

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JP6347743B2
JP6347743B2 JP2014509488A JP2014509488A JP6347743B2 JP 6347743 B2 JP6347743 B2 JP 6347743B2 JP 2014509488 A JP2014509488 A JP 2014509488A JP 2014509488 A JP2014509488 A JP 2014509488A JP 6347743 B2 JP6347743 B2 JP 6347743B2
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cocreatate
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lipid
lipids
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JP2014513135A5 (enExample
JP2014513135A (ja
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ル,ルイング
マンニーノ,ラファエル
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マティナス バイオファーマ ナノテクノロジーズ,インコーポレーテッド
マティナス バイオファーマ ナノテクノロジーズ,インコーポレーテッド
ラトガーズ, ザ ステイト ユニバーシティ オブ ニュー ジャージー
ラトガーズ, ザ ステイト ユニバーシティ オブ ニュー ジャージー
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    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1274Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
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    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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JP2014509488A 2011-05-05 2012-05-04 コクリエート組成物およびその製造および使用方法 Active JP6347743B2 (ja)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201161482996P 2011-05-05 2011-05-05
US61/482,996 2011-05-05
US201161534075P 2011-09-13 2011-09-13
US61/534,075 2011-09-13
US201161547325P 2011-10-14 2011-10-14
US61/547,325 2011-10-14
US201161570067P 2011-12-13 2011-12-13
US61/570,067 2011-12-13
US201261590531P 2012-01-25 2012-01-25
US61/590,531 2012-01-25
US201261608272P 2012-03-08 2012-03-08
US61/608,272 2012-03-08
US201261620656P 2012-04-05 2012-04-05
US61/620,656 2012-04-05
US201261636793P 2012-04-23 2012-04-23
US61/636,793 2012-04-23
PCT/US2012/036576 WO2012151517A1 (en) 2011-05-05 2012-05-04 Cochleate compositions and methods of making and using same

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JP2014513135A JP2014513135A (ja) 2014-05-29
JP2014513135A5 JP2014513135A5 (enExample) 2015-06-25
JP6347743B2 true JP6347743B2 (ja) 2018-06-27

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US (1) US20140220108A1 (enExample)
EP (1) EP2704688B1 (enExample)
JP (2) JP6347743B2 (enExample)
AU (1) AU2012250568B2 (enExample)
CA (1) CA2834788C (enExample)
ES (1) ES2741282T3 (enExample)
WO (1) WO2012151517A1 (enExample)

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JP6347743B2 (ja) * 2011-05-05 2018-06-27 マティナス バイオファーマ ナノテクノロジーズ,インコーポレーテッド コクリエート組成物およびその製造および使用方法
MX361155B (es) * 2012-07-30 2018-11-28 Matinas Biopharma Nanotechnologies Inc Cocleatos hechos con fosfatidilserina de soja.
US20150147382A1 (en) * 2013-09-23 2015-05-28 Exir Nano Sina Company Topical liposomal compositions for delivering hydrophobic drugs and methods preparing same
CN104398745A (zh) * 2014-12-07 2015-03-11 王月水 一种治疗颈肩腰腿痛、腰椎间盘突出症的中药药浴及其制备方法
KR20180004104A (ko) * 2015-03-03 2018-01-10 마티나스 바이오파마 나노테크놀로지스, 인코포레이티드 코클레이트 및 약리학적 활성제의 조직 침투를 향상시키기 위해 이를 사용하는 방법
CN108136212A (zh) * 2015-04-22 2018-06-08 马丁尼斯生物制药纳米技术公司 用于治疗分枝杆菌感染和肺病的组合物和方法
CN107920991A (zh) * 2015-06-18 2018-04-17 马丁尼斯生物制药纳米技术公司 治疗炎性疾病或病状的组合物和方法
WO2017205550A1 (en) * 2016-05-24 2017-11-30 Matinas Biopharma Nanotechnologies, Inc. Immunogenic cochleates and methods of use
CA3027668A1 (en) * 2016-07-12 2018-01-18 Matinas Biopharma Nanotechnologies, Inc. Encochleated antifungal compounds for central nervous system delivery and treatment of cryptococcus infections
AU2018337955B2 (en) * 2017-09-20 2024-01-18 Atopic Medical, Inc. Compositions and methods for treating and ameliorating respiratory conditions and inflammation of mucosa
KR101989789B1 (ko) * 2017-11-30 2019-06-18 (주) 에이치엔에이파마켐 포스파티딜세린/음이온계면활성제/염화칼슘을 이용한 코킬레이트
KR102019589B1 (ko) * 2018-01-23 2019-11-04 가톨릭대학교 산학협력단 내이에서의 약물전달용 나노입자
JP2022544077A (ja) * 2019-08-13 2022-10-17 マティナス バイオファーマ ナノテクノロジーズ,インコーポレーテッド クリプトコッカス感染症を治療する方法
EP4572770A1 (en) 2022-08-16 2025-06-25 Matinas BioPharma Nanotechnologies, Inc. Antifungal agent encapsulated in a lipid nanocrystal for treating mucormycosis
WO2024039733A1 (en) * 2022-08-16 2024-02-22 Matinas Biopharma Nanotechnologies, Inc. Methods of controlling lipid nanocrystal particle size and lipid nanocrystals produced by such methods

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