JP6334396B2 - 安定化スブチリシン組成物 - Google Patents

安定化スブチリシン組成物 Download PDF

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Publication number
JP6334396B2
JP6334396B2 JP2014517745A JP2014517745A JP6334396B2 JP 6334396 B2 JP6334396 B2 JP 6334396B2 JP 2014517745 A JP2014517745 A JP 2014517745A JP 2014517745 A JP2014517745 A JP 2014517745A JP 6334396 B2 JP6334396 B2 JP 6334396B2
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nhch
cbz
val
residue
nva
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JP2014525739A (ja
Inventor
ムンク ミケルセン リセ
ムンク ミケルセン リセ
ポンツィーニ フランチェスコ
ポンツィーニ フランチェスコ
ビザッチャ ロベルト
ビザッチャ ロベルト
カネボッティ レナト
カネボッティ レナト
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ノボザイムス アクティーゼルスカブ
ノボザイムス アクティーゼルスカブ
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Application filed by ノボザイムス アクティーゼルスカブ, ノボザイムス アクティーゼルスカブ filed Critical ノボザイムス アクティーゼルスカブ
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043Leu-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052Val-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • C07K5/06095Arg-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38663Stabilised liquid enzyme compositions
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618Protease or amylase in liquid compositions only
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2014517745A 2011-07-01 2012-06-29 安定化スブチリシン組成物 Active JP6334396B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2018085307A JP6927920B2 (ja) 2011-07-01 2018-04-26 安定化スブチリシン組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11172357.3 2011-07-01
EP11172357 2011-07-01
PCT/EP2012/062760 WO2013004636A1 (en) 2011-07-01 2012-06-29 Stabilized subtilisin composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018085307A Division JP6927920B2 (ja) 2011-07-01 2018-04-26 安定化スブチリシン組成物

Publications (2)

Publication Number Publication Date
JP2014525739A JP2014525739A (ja) 2014-10-02
JP6334396B2 true JP6334396B2 (ja) 2018-05-30

Family

ID=46506345

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014517745A Active JP6334396B2 (ja) 2011-07-01 2012-06-29 安定化スブチリシン組成物
JP2018085307A Active JP6927920B2 (ja) 2011-07-01 2018-04-26 安定化スブチリシン組成物

Family Applications After (1)

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JP2018085307A Active JP6927920B2 (ja) 2011-07-01 2018-04-26 安定化スブチリシン組成物

Country Status (14)

Country Link
US (1) US9085750B2 (enExample)
EP (1) EP2726592B1 (enExample)
JP (2) JP6334396B2 (enExample)
KR (1) KR101956895B1 (enExample)
CN (2) CN103649292B (enExample)
AU (1) AU2012280414B2 (enExample)
BR (1) BR112013033811A2 (enExample)
DK (1) DK2726592T3 (enExample)
ES (1) ES2539504T3 (enExample)
IN (1) IN2014CN00700A (enExample)
MX (1) MX346246B (enExample)
RU (1) RU2635355C2 (enExample)
WO (1) WO2013004636A1 (enExample)
ZA (1) ZA201400692B (enExample)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2970830B1 (en) 2013-03-14 2017-12-13 Novozymes A/S Enzyme and inhibitor contained in water-soluble films
EP3569611A1 (en) 2013-04-23 2019-11-20 Novozymes A/S Liquid automatic dish washing detergent compositions with stabilised subtilisin
EP2799533A1 (en) * 2013-04-30 2014-11-05 Novozymes A/S Protease and inhibitor containing water-soluble films
WO2016001319A1 (en) 2014-07-03 2016-01-07 Novozymes A/S Improved stabilization of non-protease enzyme
WO2016097352A1 (en) * 2014-12-19 2016-06-23 Novozymes A/S Protease variants and polynucleotides encoding same
DE102015210828A1 (de) 2015-06-12 2016-12-15 Henkel Ag & Co. Kgaa Phosphatfreies flüssiges Geschirrspülmittel
WO2016205755A1 (en) 2015-06-17 2016-12-22 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
CA3175255A1 (en) 2015-07-01 2017-01-05 Novozymes A/S Methods of reducing odor
US10760037B2 (en) * 2015-07-03 2020-09-01 Novozymes A/S Sulfite compositions
EP3320089B1 (en) 2015-07-06 2021-06-16 Novozymes A/S Lipase variants and polynucleotides encoding same
CN108367251A (zh) 2015-10-14 2018-08-03 诺维信公司 滤水膜的清洁
EP3408366B1 (en) * 2016-01-28 2021-12-08 Novozymes A/S Method for cleaning a medical or dental instrument
EP3464538A1 (en) 2016-05-31 2019-04-10 Novozymes A/S Stabilized liquid peroxide compositions
CN109477112B (zh) 2016-05-31 2024-09-06 丹尼斯科美国公司 蛋白酶变体及其用途
DE102016209406A1 (de) 2016-05-31 2017-11-30 Henkel Ag & Co. Kgaa Stabilisierte Enzym-haltige Wasch- und Reinigungsmittel
CA3027745A1 (en) 2016-06-17 2017-12-21 Danisco Us Inc. Protease variants and uses thereof
EP3309244A1 (en) 2016-10-11 2018-04-18 Basf Se Low temperature protease
WO2018069158A1 (en) 2016-10-11 2018-04-19 Basf Se Protease resistant to natural inhibitors
US20190264138A1 (en) 2016-11-07 2019-08-29 Danisco Us Inc. Laundry detergent composition
CN110312794B (zh) 2016-12-21 2024-04-12 丹尼斯科美国公司 吉氏芽孢杆菌进化枝丝氨酸蛋白酶
EP4520820A3 (en) 2016-12-21 2025-04-16 Danisco Us Inc Protease variants and uses thereof
CN110621778A (zh) 2017-03-15 2019-12-27 丹尼斯科美国公司 胰蛋白酶样丝氨酸蛋白酶及其用途
CN110651038B (zh) 2017-05-05 2025-02-18 诺维信公司 包含脂肪酶和亚硫酸根的组合物
EP3645692B1 (en) 2017-06-30 2025-12-31 Novozymes A/S ENZYMATIC SUSPENSION COMPOSITION
CN111479919A (zh) 2017-11-01 2020-07-31 诺维信公司 多肽以及包含此类多肽的组合物
BR112020008737A2 (pt) 2017-11-01 2020-10-13 Novozymes A/S polipeptídeos e composições que compreendam tais polipeptídeos
DE102017219993A1 (de) 2017-11-09 2019-05-09 Henkel Ag & Co. Kgaa Enzymhaltiges Wasch- oder Reinigungsmittel
EP3717643A1 (en) 2017-11-29 2020-10-07 Danisco US Inc. Subtilisin variants having improved stability
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
US20210363470A1 (en) 2018-06-19 2021-11-25 Danisco Us Inc Subtilisin variants
EP3856882A1 (en) 2018-09-27 2021-08-04 Danisco US Inc. Compositions for medical instrument cleaning
ES2981999T3 (es) 2018-10-31 2024-10-14 Henkel Ag & Co Kgaa Composiciones limpiadoras que contienen dispersinas V
EP3647397A1 (en) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Cleaning compositions containing dispersins iv
DE102018129277A1 (de) 2018-11-21 2020-05-28 Henkel Ag & Co. Kgaa Mehrkomponenten Wasch- oder Reinigungsmittel enthaltend eine Chinon-Oxidoreduktase
EP3887515A1 (en) 2018-11-28 2021-10-06 Danisco US Inc. Subtilisin variants having improved stability
CN114174504B (zh) 2019-05-24 2026-04-17 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
WO2020247582A1 (en) 2019-06-06 2020-12-10 Danisco Us Inc Methods and compositions for cleaning
EP3994148A1 (en) 2019-07-01 2022-05-11 Basf Se Peptide acetals for stabilising enzymes
WO2021009067A1 (en) 2019-07-12 2021-01-21 Novozymes A/S Enzymatic emulsions for detergents
EP4077617B1 (en) 2019-12-20 2026-03-18 Novozymes A/S Stabilized liquid boron-free enzyme compositions
EP4077656A2 (en) 2019-12-20 2022-10-26 Novozymes A/S Polypeptides having proteolytic activity and use thereof
US20240034960A1 (en) 2020-08-27 2024-02-01 Danisco Us Inc Enzymes and enzyme compositions for cleaning
WO2022063699A1 (en) 2020-09-22 2022-03-31 Basf Se Improved combination of protease and protease inhibitor with secondary enzyme
WO2023288294A1 (en) 2021-07-16 2023-01-19 Novozymes A/S Compositions and methods for improving the rainfastness of proteins on plant surfaces
EP4032966A1 (en) 2021-01-22 2022-07-27 Novozymes A/S Liquid enzyme composition with sulfite scavenger
EP4284906A1 (en) 2021-01-29 2023-12-06 Danisco US Inc. Compositions for cleaning and methods related thereto
EP4305146A1 (en) 2021-03-12 2024-01-17 Novozymes A/S Polypeptide variants
JP7411607B2 (ja) * 2021-06-17 2024-01-11 花王株式会社 洗剤用酵素安定化剤
WO2023278297A1 (en) 2021-06-30 2023-01-05 Danisco Us Inc Variant lipases and uses thereof
KR20240027617A (ko) 2021-06-30 2024-03-04 헨켈 아게 운트 코. 카게아아 폴리에스테라제 활성을 갖는 지질분해 효소를 포함하는 세정 조성물
WO2023274925A1 (en) 2021-06-30 2023-01-05 Henkel Ag & Co. Kgaa Cleaning composition with improved anti-gray performance and/or anti-pilling performance
EP4363543A1 (en) 2021-06-30 2024-05-08 Henkel AG & Co. KGaA Composition with improved moisture management performance
WO2023034486A2 (en) 2021-09-03 2023-03-09 Danisco Us Inc. Laundry compositions for cleaning
EP4448751A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and methods of use
WO2023114932A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023114939A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023168234A1 (en) 2022-03-01 2023-09-07 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
US20250311734A1 (en) 2022-05-14 2025-10-09 Novozymes A/S Compositions and Methods for Preventing, Treating, Suppressing and/or Eliminatting Phytopathogenic Infestations and Infections
CN119487167A (zh) 2022-06-21 2025-02-18 丹尼斯科美国公司 用于清洁的包含具有嗜热菌蛋白酶活性的多肽的组合物和方法
US20260078362A1 (en) 2022-09-02 2026-03-19 Danisco Us Inc. Subtilisin variants and methods related thereto
JP2025530749A (ja) 2022-09-02 2025-09-17 ダニスコ・ユーエス・インク 洗剤組成物及びそれに関連する方法
WO2024102698A1 (en) 2022-11-09 2024-05-16 Danisco Us Inc. Subtilisin variants and methods of use
EP4634219A1 (en) 2022-12-14 2025-10-22 Novozymes A/S High strength liquid protease formulations
JP2026501223A (ja) 2022-12-23 2026-01-14 ノボザイムス アクティーゼルスカブ カタラーゼ及びアミラーゼを含む洗剤組成物
WO2024163584A1 (en) 2023-02-01 2024-08-08 Danisco Us Inc. Subtilisin variants and methods of use
EP4414443A1 (en) 2023-02-09 2024-08-14 Henkel AG & Co. KGaA Cleaning composition comprising polyesterase
CN120712348A (zh) 2023-03-06 2025-09-26 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN120813242A (zh) 2023-03-16 2025-10-17 营养与生物科学美国第四公司 用于清洁和臭味控制的短芽孢杆菌发酵物提取物及其用途
CN121909283A (zh) 2023-09-28 2026-04-21 丹尼斯科美国公司 具有改善的溶解度的变体角质酶及其用途
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use
WO2025093368A1 (en) 2023-11-02 2025-05-08 Basf Se Enzyme stabilization in compositions containing a protease inhibitor
WO2025217017A1 (en) 2024-04-08 2025-10-16 Novozymes A/S Compositions and methods for increasing phosphorous availability
WO2026024922A1 (en) 2024-07-25 2026-01-29 Danisco Us Inc. Subtilisin variants and methods of use
WO2026050315A1 (en) 2024-08-29 2026-03-05 Danisco Us Inc. Subtilisin variants and methods of use

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (enExample) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
HU184368B (en) 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
EP0124317B1 (en) * 1983-04-27 1990-04-11 Ici Americas Inc. Proline derivatives
HU192646B (en) 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
WO1987000859A1 (en) 1985-08-09 1987-02-12 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
EP0258068B1 (en) 1986-08-29 1994-08-31 Novo Nordisk A/S Enzymatic detergent additive
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
US4765916A (en) 1987-03-24 1988-08-23 The Clorox Company Polymer film composition for rinse release of wash additives
US4972017A (en) 1987-03-24 1990-11-20 The Clorox Company Rinse soluble polymer film composition for wash additives
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
JP2728531B2 (ja) 1988-03-24 1998-03-18 ノボ ノルディスク アクティーゼルスカブ セルラーゼ調製品
US5648263A (en) 1988-03-24 1997-07-15 Novo Nordisk A/S Methods for reducing the harshness of a cotton-containing fabric
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
DK0528828T4 (da) 1990-04-14 1998-08-31 Genencor Internat Gmbh Alkaliske bacillus-lipaser, DNA-sekvenser, der koder herfor, og bacilli der producerer sådanne lipaser
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
CA2082279C (en) 1990-05-09 2007-09-04 Grethe Rasmussen Cellulase preparation comprising an endoglucanase enzyme
DK0548228T3 (da) 1990-09-13 1999-05-10 Novo Nordisk As Lipasevarianter
DE69133035T2 (de) 1991-01-16 2003-02-13 The Procter & Gamble Company, Cincinnati Kompakte Waschmittelzusammensetzungen mit hochaktiven Cellulasen
ES2121014T3 (es) 1991-05-01 1998-11-16 Novo Nordisk As Enzimas estabilizadas y composiciones detergentes.
WO1993012067A1 (en) 1991-12-13 1993-06-24 The Procter & Gamble Company Acylated citrate esters as peracid precursors
DK28792D0 (da) 1992-03-04 1992-03-04 Novo Nordisk As Nyt enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
KR100294361B1 (ko) 1992-07-23 2001-09-17 피아 스타르 돌연변이체알파-아밀라제,세정제,접시세척제,및액화제
DK0583534T3 (da) 1992-08-14 1997-06-16 Procter & Gamble Flydende detergenter, der indeholder et peptidaldehyd
US5792641A (en) 1992-10-06 1998-08-11 Novo Nordisk A/S Cellulase variants and detergent compositions containing cellulase variants
HU219675B (hu) 1993-02-11 2001-06-28 Genencor International Inc. Oxidatívan stabil alfa-amiláz
DE69434242T2 (de) 1993-04-27 2006-01-12 Genencor International, Inc., Palo Alto Neuartige Lipasevarianten zur Verwendung in Reinigungsmitteln
CA2165155C (en) 1993-06-14 1999-06-29 Hal Ambuter Concentrated nil-phosphate liquid automatic dishwashing detergent compositions containing enzyme
GB9314350D0 (en) 1993-07-12 1993-08-25 Zeneca Ltd Armide derivatives
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
MX9603542A (es) 1994-02-22 1997-03-29 Novo Nordisk As Metodo para preparar una variante de una enzima lipolitica.
CA2143533A1 (en) 1994-03-04 1995-09-05 Kenneth D. Kurz Antithrombotic agents
US5436229A (en) * 1994-03-04 1995-07-25 Eli Lilly And Company Bisulfite adducts of arginine aldehydes
DE69536145D1 (de) 1994-03-08 2011-04-07 Novozymes As Neuartige alkalische Zellulasen
JPH09510363A (ja) 1994-03-22 1997-10-21 ザ、プロクター、エンド、ギャンブル、カンパニー 非タンパク質プロテアーゼ抑制剤を使用するプロテアーゼ酵素の製造
US5453216A (en) 1994-04-28 1995-09-26 Creative Products Resource, Inc. Delayed-release encapsulated warewashing composition and process of use
WO1995030744A2 (en) 1994-05-04 1995-11-16 Genencor International Inc. Lipases with improved surfactant resistance
AU2884595A (en) 1994-06-20 1996-01-15 Unilever Plc Modified pseudomonas lipases and their use
AU2884695A (en) 1994-06-23 1996-01-19 Unilever Plc Modified pseudomonas lipases and their use
US5919691A (en) 1994-10-06 1999-07-06 Novo Nordisk A/S Enzyme and enzyme preparation with endoglucanase activity
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
CN1167503A (zh) 1994-10-26 1997-12-10 诺沃挪第克公司 一种具有脂解活性的酶
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
CN1182451A (zh) 1995-03-17 1998-05-20 诺沃挪第克公司 新的内切葡聚糖酶
EP0839186B1 (en) 1995-07-14 2004-11-10 Novozymes A/S A modified enzyme with lipolytic activity
JP4068142B2 (ja) 1995-08-11 2008-03-26 ノボザイムス アクティーゼルスカブ 新規の脂肪分解酵素
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
AU3938997A (en) 1996-08-26 1998-03-19 Novo Nordisk A/S A novel endoglucanase
BR9711479B1 (pt) 1996-09-17 2009-08-11 variante de celulase tendo uma resistência aumentada a tensìdeo de ánion.
EP0929639B1 (en) * 1996-09-24 2002-11-13 The Procter & Gamble Company Liquid detergents containing proteolytic enzyme, peptide aldehyde and calcium ions
CN1238002A (zh) 1996-09-24 1999-12-08 普罗格特-甘布尔公司 含有蛋白水解酶、肽醛和硼酸源的液体洗涤剂
CN1238003A (zh) 1996-09-24 1999-12-08 普罗格特-甘布尔公司 含有蛋白酶和蛋白酶抑制剂的液体洗衣洗涤剂组合物
CA2266497C (en) 1996-09-24 2002-12-31 John Mcmillan Mciver Liquid detergents containing proteolytic enzyme and protease inhibitors
BR9713470A (pt) * 1996-09-24 2000-04-11 Procter & Gamble Detergentes lìquidos contendo enzima proteolìtica e inibidores da protease
EP0934389B1 (en) 1996-10-18 2003-12-10 The Procter & Gamble Company Detergent compositions
CN1530443A (zh) 1996-11-04 2004-09-22 ŵ����÷�����޹�˾ 枯草杆菌酶变异体和组合物
AU4772697A (en) 1996-11-04 1998-05-29 Novo Nordisk A/S Subtilase variants and compositions
WO1998034946A1 (en) 1997-02-12 1998-08-13 Massachusetts Institute Of Technology Daxx, a novel fas-binding protein that activates jnk and apoptosis
NZ500045A (en) 1997-04-18 2001-02-23 Cephalon Inc Peptidyl-2-amino-1-hydroxyalkanesulfonic acid cysteine protease inhibitors
EP1002061A1 (en) 1997-07-04 2000-05-24 Novo Nordisk A/S FAMILY 6 ENDO-1,4-$g(b)-GLUCANASE VARIANTS AND CLEANING COMPOSIT IONS CONTAINING THEM
WO1999027083A1 (en) 1997-11-24 1999-06-03 Novo Nordisk A/S PECTIN DEGRADING ENZYMES FROM $i(BACILLUS LICHENIFORMIS)
AU1482599A (en) 1997-11-24 1999-06-15 Novo Nordisk A/S Novel pectate lyases
US6124127A (en) 1997-11-24 2000-09-26 Novo Nordisk A/S Pectate lyase
EP2284272B1 (en) 1998-06-10 2014-08-13 Novozymes A/S Mannanases
KR20010108379A (ko) 1999-03-31 2001-12-07 피아 스타르 리파제 변이체
CA2394971C (en) 1999-12-15 2016-01-19 Novozymes A/S Subtilase variants having an improved wash performance on egg stains
KR20020077421A (ko) 2000-02-08 2002-10-11 에프. 호프만-라 로슈 아게 동물 사료에서 산-안정성 서브틸리신 프로테아제의 사용
DE60137510D1 (de) 2000-07-19 2009-03-12 Novozymes As Zellwandabbauende enzymvarianten
GB2365018A (en) 2000-07-24 2002-02-13 Procter & Gamble Water soluble pouches
EP1389228B1 (en) 2001-05-14 2009-03-11 Novozymes A/S Detergent compositions comprising bacillus subtilis pectate lyases
GB0114847D0 (en) 2001-06-18 2001-08-08 Unilever Plc Water soluble package and liquid contents thereof
DK200101090A (da) 2001-07-12 2001-08-16 Novozymes As Subtilase variants
GB0207430D0 (en) 2002-03-28 2002-05-08 Unilever Plc Liquid cleaning compositionsand their use
CN100482791C (zh) 2002-05-14 2009-04-29 诺和酶股份有限公司 果胶酸裂解酶变体
CN102766545B (zh) 2003-05-07 2014-08-06 诺维信公司 变体枯草杆菌蛋白酶(枯草杆菌酶)
ES2629332T3 (es) 2006-01-23 2017-08-08 Novozymes A/S Variantes de lipasa
US20080009431A1 (en) 2006-06-05 2008-01-10 Jean-Pol Boutique Enzyme stabilization
BRPI0712344A2 (pt) 2006-06-05 2012-01-31 Procter & Gamble estabilização de enzimas
ATE503826T1 (de) 2007-07-02 2011-04-15 Procter & Gamble Mehrkammerbeutel enthaltend waschmittel
EP2250259B1 (en) 2008-02-29 2016-08-31 Novozymes A/S Polypeptides having lipase activity and polynucleotides encoding same
MX2010010348A (es) 2008-03-26 2010-11-09 Novozymes As Composiciones de enzimas liquidas estabilizadas.
PL2310483T3 (pl) 2008-07-07 2016-09-30 Kompozycja enzymatyczna zawierająca cząstki polimerowe zawierające enzym
WO2010055052A1 (en) 2008-11-13 2010-05-20 Novozymes A/S Detergent composition
US20120149625A1 (en) 2009-09-25 2012-06-14 Novozymes A/S Detergent Composition
MX339581B (es) 2009-09-25 2016-06-01 Novozymes As Variantes de subtilasa.

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EP2726592A1 (en) 2014-05-07
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US20140336098A1 (en) 2014-11-13
KR20140053102A (ko) 2014-05-07
JP6927920B2 (ja) 2021-09-01
WO2013004636A1 (en) 2013-01-10
JP2018139598A (ja) 2018-09-13
DK2726592T3 (en) 2015-07-06
ZA201400692B (en) 2015-05-27
MX2014000060A (es) 2014-05-01
BR112013033811A2 (pt) 2017-02-14
US9085750B2 (en) 2015-07-21
CN107858217B (zh) 2021-03-23
AU2012280414B2 (en) 2015-06-25
IN2014CN00700A (enExample) 2015-04-03
RU2014103501A (ru) 2015-08-10
RU2635355C2 (ru) 2017-11-13
AU2012280414A1 (en) 2014-01-16
CN103649292B (zh) 2017-11-28
MX346246B (es) 2017-03-13
EP2726592B1 (en) 2015-04-01
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