MX346246B - Composicion de subtilisina estabilizada. - Google Patents

Composicion de subtilisina estabilizada.

Info

Publication number
MX346246B
MX346246B MX2014000060A MX2014000060A MX346246B MX 346246 B MX346246 B MX 346246B MX 2014000060 A MX2014000060 A MX 2014000060A MX 2014000060 A MX2014000060 A MX 2014000060A MX 346246 B MX346246 B MX 346246B
Authority
MX
Mexico
Prior art keywords
hydrosulfite adduct
peptide aldehyde
peptide
avoid
effective
Prior art date
Application number
MX2014000060A
Other languages
English (en)
Other versions
MX2014000060A (es
Inventor
Munch Mikkelsen Lise
Ponzini Francesco
Bisaccia Roberto
Canevotti Renato
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46506345&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX346246(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes As filed Critical Novozymes As
Publication of MX2014000060A publication Critical patent/MX2014000060A/es
Publication of MX346246B publication Critical patent/MX346246B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38663—Stabilised liquid enzyme compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618—Protease or amylase in liquid compositions only
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se refiere a una conversión de un aldehído peptídico en un aducto de hidrosulfito puede utilizarse para aumentar la solubilidad acuosa en la purificación de los aldehídos peptídicos. Ventajosamente, este aducto de hidrosulfito es efectivo como inhibidor y estabilizador de subtilisina y puede utilizarse también para estabilizar una segunda enzima si está presente. El aducto de hidrosulfito es efectivo como inhibidor de subtilisina y mantiene su efecto inhibidor y estabilizador en un detergente líquido durante el almacenamiento. De esta forma, el uso del aducto de hidrosulfito puede evitar el costo y el tiempo de convertirlo de nuevo en aldehído peptídicos y puede evitarse el secado posterior del aldehído peptídico, y esto puede evitar el inconveniente de manejar el aldehído peptídico en forma de polvo o como una solución acuosa altamente diluida.
MX2014000060A 2011-07-01 2012-06-29 Composicion de subtilisina estabilizada. MX346246B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11172357 2011-07-01
PCT/EP2012/062760 WO2013004636A1 (en) 2011-07-01 2012-06-29 Stabilized subtilisin composition

Publications (2)

Publication Number Publication Date
MX2014000060A MX2014000060A (es) 2014-05-01
MX346246B true MX346246B (es) 2017-03-13

Family

ID=46506345

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000060A MX346246B (es) 2011-07-01 2012-06-29 Composicion de subtilisina estabilizada.

Country Status (14)

Country Link
US (1) US9085750B2 (es)
EP (1) EP2726592B1 (es)
JP (2) JP6334396B2 (es)
KR (1) KR101956895B1 (es)
CN (2) CN107858217B (es)
AU (1) AU2012280414B2 (es)
BR (1) BR112013033811A2 (es)
DK (1) DK2726592T3 (es)
ES (1) ES2539504T3 (es)
IN (1) IN2014CN00700A (es)
MX (1) MX346246B (es)
RU (1) RU2635355C2 (es)
WO (1) WO2013004636A1 (es)
ZA (1) ZA201400692B (es)

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CN107858217A (zh) 2018-03-30
JP6927920B2 (ja) 2021-09-01
IN2014CN00700A (es) 2015-04-03
MX2014000060A (es) 2014-05-01
RU2014103501A (ru) 2015-08-10
AU2012280414B2 (en) 2015-06-25
JP6334396B2 (ja) 2018-05-30
ZA201400692B (en) 2015-05-27
CN103649292B (zh) 2017-11-28
BR112013033811A2 (pt) 2017-02-14
JP2018139598A (ja) 2018-09-13
CN107858217B (zh) 2021-03-23
KR101956895B1 (ko) 2019-03-12
CN103649292A (zh) 2014-03-19
US9085750B2 (en) 2015-07-21
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DK2726592T3 (en) 2015-07-06
RU2635355C2 (ru) 2017-11-13
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AU2012280414A1 (en) 2014-01-16
US20140336098A1 (en) 2014-11-13
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KR20140053102A (ko) 2014-05-07

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