MX346246B - Composicion de subtilisina estabilizada. - Google Patents

Composicion de subtilisina estabilizada.

Info

Publication number
MX346246B
MX346246B MX2014000060A MX2014000060A MX346246B MX 346246 B MX346246 B MX 346246B MX 2014000060 A MX2014000060 A MX 2014000060A MX 2014000060 A MX2014000060 A MX 2014000060A MX 346246 B MX346246 B MX 346246B
Authority
MX
Mexico
Prior art keywords
hydrosulfite adduct
peptide aldehyde
peptide
avoid
effective
Prior art date
Application number
MX2014000060A
Other languages
English (en)
Other versions
MX2014000060A (es
Inventor
Munch Mikkelsen Lise
Ponzini Francesco
Bisaccia Roberto
Canevotti Renato
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46506345&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX346246(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes As filed Critical Novozymes As
Publication of MX2014000060A publication Critical patent/MX2014000060A/es
Publication of MX346246B publication Critical patent/MX346246B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38663—Stabilised liquid enzyme compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618—Protease or amylase in liquid compositions only
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se refiere a una conversión de un aldehído peptídico en un aducto de hidrosulfito puede utilizarse para aumentar la solubilidad acuosa en la purificación de los aldehídos peptídicos. Ventajosamente, este aducto de hidrosulfito es efectivo como inhibidor y estabilizador de subtilisina y puede utilizarse también para estabilizar una segunda enzima si está presente. El aducto de hidrosulfito es efectivo como inhibidor de subtilisina y mantiene su efecto inhibidor y estabilizador en un detergente líquido durante el almacenamiento. De esta forma, el uso del aducto de hidrosulfito puede evitar el costo y el tiempo de convertirlo de nuevo en aldehído peptídicos y puede evitarse el secado posterior del aldehído peptídico, y esto puede evitar el inconveniente de manejar el aldehído peptídico en forma de polvo o como una solución acuosa altamente diluida.
MX2014000060A 2011-07-01 2012-06-29 Composicion de subtilisina estabilizada. MX346246B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11172357 2011-07-01
PCT/EP2012/062760 WO2013004636A1 (en) 2011-07-01 2012-06-29 Stabilized subtilisin composition

Publications (2)

Publication Number Publication Date
MX2014000060A MX2014000060A (es) 2014-05-01
MX346246B true MX346246B (es) 2017-03-13

Family

ID=46506345

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000060A MX346246B (es) 2011-07-01 2012-06-29 Composicion de subtilisina estabilizada.

Country Status (14)

Country Link
US (1) US9085750B2 (es)
EP (1) EP2726592B1 (es)
JP (2) JP6334396B2 (es)
KR (1) KR101956895B1 (es)
CN (2) CN107858217B (es)
AU (1) AU2012280414B2 (es)
BR (1) BR112013033811A2 (es)
DK (1) DK2726592T3 (es)
ES (1) ES2539504T3 (es)
IN (1) IN2014CN00700A (es)
MX (1) MX346246B (es)
RU (1) RU2635355C2 (es)
WO (1) WO2013004636A1 (es)
ZA (1) ZA201400692B (es)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014152674A1 (en) 2013-03-14 2014-09-25 Novozymes A/S Enzyme and inhibitor containing water-soluble films
CN105164147B (zh) * 2013-04-23 2020-03-03 诺维信公司 具有稳定的枯草杆菌蛋白酶的液体自动餐具清洗洗涤剂组合物
EP2799533A1 (en) * 2013-04-30 2014-11-05 Novozymes A/S Protease and inhibitor containing water-soluble films
CN106471110A (zh) * 2014-07-03 2017-03-01 诺维信公司 改进的非蛋白酶类酶稳定化
EP3741848A3 (en) * 2014-12-19 2021-02-17 Novozymes A/S Protease variants and polynucleotides encoding same
DE102015210828A1 (de) 2015-06-12 2016-12-15 Henkel Ag & Co. Kgaa Phosphatfreies flüssiges Geschirrspülmittel
JP7015695B2 (ja) 2015-06-17 2022-02-03 ダニスコ・ユーエス・インク バチルス・ギブソニイ（Ｂａｃｉｌｌｕｓ ｇｉｂｓｏｎｉｉ）クレードセリンプロテアーゼ
MX394221B (es) 2015-07-01 2025-03-24 Novozymes As Metodos de reduccion de olor.
CN107995922B (zh) * 2015-07-03 2021-12-28 诺维信公司 在亚硫酸盐的存在下具有改进的稳定性的洗涤剂组合物
CN107969136B (zh) 2015-07-06 2021-12-21 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
CN108367251A (zh) 2015-10-14 2018-08-03 诺维信公司 滤水膜的清洁
WO2017129331A1 (en) * 2016-01-28 2017-08-03 Novozymes A/S Method for cleaning a medical or dental instrument
US20190218479A1 (en) 2016-05-31 2019-07-18 Novozymes A/S Stabilized Liquid Peroxide Compositions
MX2018014768A (es) 2016-05-31 2019-03-06 Danisco Us Inc Variantes de proteasa y sus usos.
DE102016209406A1 (de) 2016-05-31 2017-11-30 Henkel Ag & Co. Kgaa Stabilisierte Enzym-haltige Wasch- und Reinigungsmittel
JP7152319B2 (ja) 2016-06-17 2022-10-12 ダニスコ・ユーエス・インク プロテアーゼ変異体およびその使用
WO2018069158A1 (en) 2016-10-11 2018-04-19 Basf Se Protease resistant to natural inhibitors
EP3309244A1 (en) 2016-10-11 2018-04-18 Basf Se Low temperature protease
WO2018085524A2 (en) 2016-11-07 2018-05-11 Danisco Us Inc Laundry detergent composition
EP3559227B1 (en) 2016-12-21 2025-02-19 Danisco US Inc. Protease variants and uses thereof
WO2018118950A1 (en) 2016-12-21 2018-06-28 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
WO2018169750A1 (en) 2017-03-15 2018-09-20 Danisco Us Inc Trypsin-like serine proteases and uses thereof
US11078445B2 (en) 2017-05-05 2021-08-03 Novozymes A/S Compositions comprising lipase and sulfite
US20200181542A1 (en) 2017-06-30 2020-06-11 Novozymes A/S Enzyme Slurry Composition
EP3704219B1 (en) 2017-11-01 2024-01-10 Novozymes A/S Polypeptides and compositions comprising such polypeptides
WO2019086528A1 (en) 2017-11-01 2019-05-09 Novozymes A/S Polypeptides and compositions comprising such polypeptides
DE102017219993A1 (de) 2017-11-09 2019-05-09 Henkel Ag & Co. Kgaa Enzymhaltiges Wasch- oder Reinigungsmittel
WO2019108599A1 (en) 2017-11-29 2019-06-06 Danisco Us Inc Subtilisin variants having improved stability
EP3799601A1 (en) 2018-06-19 2021-04-07 Danisco US Inc. Subtilisin variants
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
CN113166682A (zh) 2018-09-27 2021-07-23 丹尼斯科美国公司 用于医疗器械清洁的组合物
EP3647398B1 (en) 2018-10-31 2024-05-15 Henkel AG & Co. KGaA Cleaning compositions containing dispersins v
EP3647397A1 (en) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Cleaning compositions containing dispersins iv
DE102018129277A1 (de) 2018-11-21 2020-05-28 Henkel Ag & Co. Kgaa Mehrkomponenten Wasch- oder Reinigungsmittel enthaltend eine Chinon-Oxidoreduktase
EP3887515A1 (en) 2018-11-28 2021-10-06 Danisco US Inc. Subtilisin variants having improved stability
WO2020242858A1 (en) 2019-05-24 2020-12-03 Danisco Us Inc Subtilisin variants and methods of use
WO2020247582A1 (en) 2019-06-06 2020-12-10 Danisco Us Inc Methods and compositions for cleaning
EP3994148A1 (en) 2019-07-01 2022-05-11 Basf Se Peptide acetals for stabilising enzymes
CN114364778B (zh) 2019-07-12 2024-08-13 诺维信公司 用于洗涤剂的酶性乳剂
EP4077656A2 (en) 2019-12-20 2022-10-26 Novozymes A/S Polypeptides having proteolytic activity and use thereof
US20220411726A1 (en) 2019-12-20 2022-12-29 Novozymes A/S Stabilized liquid boron-free enzyme compositions
US20240034960A1 (en) 2020-08-27 2024-02-01 Danisco Us Inc Enzymes and enzyme compositions for cleaning
US20240240114A1 (en) 2020-09-22 2024-07-18 Basf Se Improved Combination of Protease and Protease Inhibitor with Secondary Enzyme
WO2023288294A1 (en) 2021-07-16 2023-01-19 Novozymes A/S Compositions and methods for improving the rainfastness of proteins on plant surfaces
EP4032966A1 (en) 2021-01-22 2022-07-27 Novozymes A/S Liquid enzyme composition with sulfite scavenger
CN116997642A (zh) 2021-01-29 2023-11-03 丹尼斯科美国公司 清洁组合物及其相关的方法
EP4305146A1 (en) 2021-03-12 2024-01-17 Novozymes A/S Polypeptide variants
JP7411607B2 (ja) * 2021-06-17 2024-01-11 花王株式会社 洗剤用酵素安定化剤
US20240287418A1 (en) 2021-06-30 2024-08-29 Henkel Ag & Co. Kgaa Cleaning composition with improved anti-gray performance and/or anti-pilling performance
US20240240115A1 (en) 2021-06-30 2024-07-18 Henkel Ag & Co. Kgaa Composition with improved moisture management performance
WO2023278297A1 (en) 2021-06-30 2023-01-05 Danisco Us Inc Variant lipases and uses thereof
US20240287417A1 (en) 2021-06-30 2024-08-29 Henkel Ag & Co. Kgaa Cleaning composition comprising lipolytic enzyme having polyesterase activity
CN117916354A (zh) 2021-09-03 2024-04-19 丹尼斯科美国公司 用于清洁的衣物洗涤组合物
EP4448750A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and uses thereof
CN118679252A (zh) 2021-12-16 2024-09-20 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
WO2023114936A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
US20250163396A1 (en) 2022-03-01 2025-05-22 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
CA3257053A1 (en) 2022-05-14 2023-11-23 Novozymes A/S COMPOSITIONS AND METHODS FOR THE PREVENTION, TREATMENT, SUPPRESSION AND/OR ELIMINATION OF PHYTOPATHOGENIC INFESTATIONS AND INFECTIONS
WO2023250301A1 (en) 2022-06-21 2023-12-28 Danisco Us Inc. Methods and compositions for cleaning comprising a polypeptide having thermolysin activity
EP4581138A1 (en) 2022-09-02 2025-07-09 Danisco US Inc. Subtilisin variants and methods related thereto
WO2024050346A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Detergent compositions and methods related thereto
WO2024102698A1 (en) 2022-11-09 2024-05-16 Danisco Us Inc. Subtilisin variants and methods of use
WO2024126697A1 (en) 2022-12-14 2024-06-20 Novozymes A/S High strength liquid protease formulations
KR20250130619A (ko) 2022-12-23 2025-09-02 노보자임스 에이/에스 카탈라제 및 아밀라제를 포함하는 세제 조성물
EP4658776A1 (en) 2023-02-01 2025-12-10 Danisco US Inc. Subtilisin variants and methods of use
EP4414443A1 (en) 2023-02-09 2024-08-14 Henkel AG & Co. KGaA Cleaning composition comprising polyesterase
EP4677080A1 (en) 2023-03-06 2026-01-14 Danisco US Inc. Subtilisin variants and methods of use
WO2024191711A1 (en) 2023-03-16 2024-09-19 Nutrition & Biosciences USA 4, Inc. Brevibacillus fermentate extracts for cleaning and malodor control and use thereof
WO2025071996A1 (en) 2023-09-28 2025-04-03 Danisco Us Inc. Variant cutinase enzymes with improved solubility and uses thereof
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use
WO2025093368A1 (en) 2023-11-02 2025-05-08 Basf Se Enzyme stabilization in compositions containing a protease inhibitor
WO2025217017A1 (en) 2024-04-08 2025-10-16 Novozymes A/S Compositions and methods for increasing phosphorous availability
WO2026024921A1 (en) 2024-07-25 2026-01-29 The Procter & Gamble Company Detergent composition comprising a subtilisin variant and methods of use

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (es) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
HU184368B (en) 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
EP0124317B1 (en) * 1983-04-27 1990-04-11 Ici Americas Inc. Proline derivatives
HU192646B (en) 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
ATE110768T1 (de) 1986-08-29 1994-09-15 Novo Nordisk As Enzymhaltiger reinigungsmittelzusatz.
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
US4765916A (en) 1987-03-24 1988-08-23 The Clorox Company Polymer film composition for rinse release of wash additives
US4972017A (en) 1987-03-24 1990-11-20 The Clorox Company Rinse soluble polymer film composition for wash additives
ATE125865T1 (de) 1987-08-28 1995-08-15 Novo Nordisk As Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen.
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体ｄｎａ、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
JP2728531B2 (ja) 1988-03-24 1998-03-18 ノボ ノルディスク アクティーゼルスカブ セルラーゼ調製品
US5776757A (en) 1988-03-24 1998-07-07 Novo Nordisk A/S Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
ATE107355T1 (de) 1990-04-14 1994-07-15 Kali Chemie Ag Alkalische bacillus-lipasen, hierfür codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren.
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
DK0531372T4 (da) 1990-05-09 2004-08-09 Novozymes As Cellulasepræparat omfattende et endoglucanaseenzym
WO1992005249A1 (en) 1990-09-13 1992-04-02 Novo Nordisk A/S Lipase variants
DE69133035T2 (de) 1991-01-16 2003-02-13 The Procter & Gamble Company, Cincinnati Kompakte Waschmittelzusammensetzungen mit hochaktiven Cellulasen
KR100258460B1 (ko) 1991-05-01 2000-06-01 한센 핀 베네드 안정화 효소 및 세제 조성물
WO1993012067A1 (en) 1991-12-13 1993-06-24 The Procter & Gamble Company Acylated citrate esters as peracid precursors
DK28792D0 (da) 1992-03-04 1992-03-04 Novo Nordisk As Nyt enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
DE69334295D1 (de) 1992-07-23 2009-11-12 Novo Nordisk As MUTIERTE -g(a)-AMYLASE, WASCHMITTEL UND GESCHIRRSPÜLMITTEL
DK0583534T3 (da) 1992-08-14 1997-06-16 Procter & Gamble Flydende detergenter, der indeholder et peptidaldehyd
ATE262035T1 (de) 1992-10-06 2004-04-15 Novozymes As Zellulosevarianten
WO1994018314A1 (en) 1993-02-11 1994-08-18 Genencor International, Inc. Oxidatively stable alpha-amylase
CN1108457A (zh) 1993-04-27 1995-09-13 吉斯特·布罗卡迪斯股份有限公司 用于洗涤剂领域的新的脂酶变异体
EP0703974B1 (en) 1993-06-14 1998-09-02 The Procter & Gamble Company Concentrated nil-phosphate liquid automatic dishwashing detergent compositions containing enzyme
GB9314350D0 (en) 1993-07-12 1993-08-25 Zeneca Ltd Armide derivatives
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
BR9506861A (pt) 1994-02-22 1997-09-23 Novo Nordisk As Processo para preparar e produzir uma variante de uma enzima lipolítica originária variante de enzima liplítica construção de dna vetor célula hospedeira aditivo detergente e composição detergente
US5436229A (en) * 1994-03-04 1995-07-25 Eli Lilly And Company Bisulfite adducts of arginine aldehydes
CA2143533A1 (en) 1994-03-04 1995-09-05 Kenneth D. Kurz Antithrombotic agents
CA2185101A1 (en) 1994-03-08 1995-09-14 Martin Schulein Novel alkaline cellulases
EP0751991A1 (en) 1994-03-22 1997-01-08 The Procter & Gamble Company Protease enzyme manufacture using non-protein protease inhibitors
US5453216A (en) 1994-04-28 1995-09-26 Creative Products Resource, Inc. Delayed-release encapsulated warewashing composition and process of use
US6017866A (en) 1994-05-04 2000-01-25 Genencor International, Inc. Lipases with improved surfactant resistance
AU2884595A (en) 1994-06-20 1996-01-15 Unilever Plc Modified pseudomonas lipases and their use
AU2884695A (en) 1994-06-23 1996-01-19 Unilever Plc Modified pseudomonas lipases and their use
ATE389012T1 (de) 1994-10-06 2008-03-15 Novozymes As Ein enzympräparat mit endoglucanase aktivität
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
US5827719A (en) 1994-10-26 1998-10-27 Novo Nordisk A/S Enzyme with lipolytic activity
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
CN101173263A (zh) 1995-03-17 2008-05-07 诺沃奇梅兹有限公司 新的内切葡聚糖酶
ATE282087T1 (de) 1995-07-14 2004-11-15 Novozymes As Modifiziertes enzym mit lipolytischer aktivität
ATE267248T1 (de) 1995-08-11 2004-06-15 Novozymes As Neuartige lipolytische enzyme
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
WO1998008940A1 (en) 1996-08-26 1998-03-05 Novo Nordisk A/S A novel endoglucanase
CA2265914C (en) 1996-09-17 2011-05-03 Novo Nordisk A/S Cellulase variants
EP0929638A1 (en) 1996-09-24 1999-07-21 The Procter & Gamble Company Liquid detergents containing proteolytic enzyme and protease inhibitors
CA2266487A1 (en) 1996-09-24 1998-04-02 Laurence Anthony Smith Liquid detergents containing proteolytic enzyme, peptide aldehyde and a source of boric acid
CA2266525A1 (en) 1996-09-24 1998-04-02 Charles Winston Saunders Liquid laundry detergent compositions containing proteolytic enzyme and protease inhibitors
CN1113088C (zh) 1996-09-24 2003-07-02 普罗格特-甘布尔公司 含有蛋白酶和蛋白酶抑制剂的液体洗涤剂
JP2000506930A (ja) * 1996-09-24 2000-06-06 ザ、プロクター、エンド、ギャンブル、カンパニー タンパク質分解酵素、ペプチドアルデヒドおよびカルシウムイオンを含有した液体洗剤
CA2268772C (en) 1996-10-18 2008-12-09 The Procter & Gamble Company Detergent compositions comprising an amylolytic enzyme and a cationic surfactant
BR9712473B1 (pt) 1996-11-04 2009-08-11 variantes de subtilase e composições.
CN1136311C (zh) 1996-11-04 2004-01-28 诺沃奇梅兹有限公司 枯草杆菌酶变异体和组合物
US6159731A (en) 1997-02-12 2000-12-12 Massachusetts Institute Of Technology Daxx, a Fas-binding protein that activates JNK and apoptosis
ES2252831T3 (es) * 1997-04-18 2006-05-16 Cephalon, Inc. Acidos peptidil-2-amino-1-hidroxialcanosulfonico utilizado como inhibidor de la cisteina proteasa.
EP1002061A1 (en) 1997-07-04 2000-05-24 Novo Nordisk A/S FAMILY 6 ENDO-1,4-$g(b)-GLUCANASE VARIANTS AND CLEANING COMPOSIT IONS CONTAINING THEM
WO1999027083A1 (en) 1997-11-24 1999-06-03 Novo Nordisk A/S PECTIN DEGRADING ENZYMES FROM $i(BACILLUS LICHENIFORMIS)
US6124127A (en) 1997-11-24 2000-09-26 Novo Nordisk A/S Pectate lyase
TR200001489T2 (tr) 1997-11-24 2000-11-21 Novo Nordisk A/S Yeni pektat liazlar.
CN100497614C (zh) 1998-06-10 2009-06-10 诺沃奇梅兹有限公司 甘露聚糖酶
JP4523178B2 (ja) 1999-03-31 2010-08-11 ノボザイムス アクティーゼルスカブ リパーゼ変異体
CN1415011B (zh) 1999-12-15 2010-12-08 诺沃奇梅兹有限公司 对蛋渍具有改进洗涤性能的枯草杆菌酶变体
KR20020077421A (ko) 2000-02-08 2002-10-11 에프. 호프만-라 로슈 아게 동물 사료에서 산-안정성 서브틸리신 프로테아제의 사용
WO2002006442A2 (en) 2000-07-19 2002-01-24 Novozymes A/S Cell-wall degrading enzyme variants
GB2365018A (en) 2000-07-24 2002-02-13 Procter & Gamble Water soluble pouches
JP4213475B2 (ja) 2001-05-14 2009-01-21 ノボザイムス アクティーゼルスカブ バシラス・ズブチリスペクチン酸リアーゼを含んでなる洗浄剤組成物
GB0114847D0 (en) 2001-06-18 2001-08-08 Unilever Plc Water soluble package and liquid contents thereof
DK200101090A (da) 2001-07-12 2001-08-16 Novozymes As Subtilase variants
GB0207430D0 (en) 2002-03-28 2002-05-08 Unilever Plc Liquid cleaning compositionsand their use
MXPA04011011A (es) 2002-05-14 2005-02-14 Novozymes As Variantes de pectato liasa.
BRPI0409992A (pt) 2003-05-07 2006-05-09 Novozymes As enzima subtilase, polinucleotìdeo isolado, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, método para produzir a subtilase, composição limpadora ou detergente, usos de uma subtilase e de uma composição limpadora ou detergente, e, métodos para limpar ou lavar louças, lavar uma superfìcie dura ou lavar roupas e para remover manchas de ovo de uma superfìcie dura ou de roupas para lavar
ES2628940T3 (es) 2006-01-23 2017-08-04 Novozymes A/S Variantes de lipasa
MX2008015590A (es) 2006-06-05 2008-12-18 Procter & Gamble Estabilizacion de enzima.
WO2007141736A2 (en) * 2006-06-05 2007-12-13 The Procter & Gamble Company Enzyme stabilization
ES2364193T3 (es) 2007-07-02 2011-08-26 THE PROCTER & GAMBLE COMPANY Composición para bolsa de múltiples compartimentos para el lavado de ropa.
US7919298B2 (en) 2008-02-29 2011-04-05 Novozymes A/S Polypeptides having lipase activity and polynucleotides encoding same
MX2010010348A (es) 2008-03-26 2010-11-09 Novozymes As Composiciones de enzimas liquidas estabilizadas.
PL2310483T3 (pl) 2008-07-07 2016-09-30 Kompozycja enzymatyczna zawierająca cząstki polimerowe zawierające enzym
US10577568B2 (en) 2008-11-13 2020-03-03 Novozymes A/S Detergent composition
KR20120090991A (ko) 2009-09-25 2012-08-17 노보자임스 에이/에스 세제 조성물
CN102648273B (zh) 2009-09-25 2017-04-26 诺维信公司 枯草蛋白酶变体

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MX2014000060A (es) 2014-05-01
CN103649292A (zh) 2014-03-19
CN107858217A (zh) 2018-03-30
EP2726592B1 (en) 2015-04-01
KR20140053102A (ko) 2014-05-07
RU2014103501A (ru) 2015-08-10
DK2726592T3 (en) 2015-07-06
KR101956895B1 (ko) 2019-03-12
AU2012280414B2 (en) 2015-06-25
WO2013004636A1 (en) 2013-01-10
JP6334396B2 (ja) 2018-05-30
BR112013033811A2 (pt) 2017-02-14
US20140336098A1 (en) 2014-11-13
AU2012280414A1 (en) 2014-01-16
JP6927920B2 (ja) 2021-09-01
EP2726592A1 (en) 2014-05-07
US9085750B2 (en) 2015-07-21
JP2018139598A (ja) 2018-09-13
ZA201400692B (en) 2015-05-27
ES2539504T3 (es) 2015-07-01
CN103649292B (zh) 2017-11-28
IN2014CN00700A (es) 2015-04-03
RU2635355C2 (ru) 2017-11-13
CN107858217B (zh) 2021-03-23

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