JP6319515B2 - タンパク質の製造方法 - Google Patents

タンパク質の製造方法 Download PDF

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Publication number
JP6319515B2
JP6319515B2 JP2017519022A JP2017519022A JP6319515B2 JP 6319515 B2 JP6319515 B2 JP 6319515B2 JP 2017519022 A JP2017519022 A JP 2017519022A JP 2017519022 A JP2017519022 A JP 2017519022A JP 6319515 B2 JP6319515 B2 JP 6319515B2
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protein
culture
xylan
inducer
strain
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Japanese (ja)
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JPWO2017170917A1 (ja
Inventor
小林　宏治
宏治 小林
紳吾 平松
紳吾 平松
山田　勝成
勝成 山田
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Toray Industries Inc
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Toray Industries Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/248—Xylanases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K1/00—Glucose; Glucose-containing syrups
    • C13K1/02—Glucose; Glucose-containing syrups obtained by saccharification of cellulosic materials
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K13/00—Sugars not otherwise provided for in this class

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2017519022A 2016-03-31 2017-03-30 タンパク質の製造方法 Expired - Fee Related JP6319515B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2018025165A JP6939624B2 (ja) 2016-03-31 2018-02-15 タンパク質の製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016070584 2016-03-31
JP2016070584 2016-03-31
PCT/JP2017/013377 WO2017170917A1 (ja) 2016-03-31 2017-03-30 タンパク質の製造方法

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JP6319515B2 true JP6319515B2 (ja) 2018-05-09

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US (1) US11453899B2 (cg-RX-API-DMAC7.html)
EP (2) EP3974527A1 (cg-RX-API-DMAC7.html)
JP (2) JP6319515B2 (cg-RX-API-DMAC7.html)
CN (1) CN108779456B (cg-RX-API-DMAC7.html)
AU (1) AU2017239832B2 (cg-RX-API-DMAC7.html)
CA (1) CA3019297A1 (cg-RX-API-DMAC7.html)
PH (1) PH12018502082A1 (cg-RX-API-DMAC7.html)
WO (1) WO2017170917A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI701249B (zh) * 2015-03-13 2020-08-11 德商４Ｓｃ製藥公司 Ｋv１.３抑制劑及其醫學應用
CA3019284A1 (en) * 2016-03-31 2017-10-05 Toray Industries, Inc. Method for producing xylo-oligosaccharide
CN112334582B (zh) * 2018-07-04 2025-03-11 花王株式会社 蛋白质的制造方法
BR112021001743A2 (pt) * 2018-07-30 2021-04-27 Toray Industries, Inc. cepas mutantes de um fungo filamentoso do gênero trichoderma e métodos para a produção de uma proteína e para a produção de uma celulase
CN111500619B (zh) * 2019-01-31 2023-06-23 中国科学院分子植物科学卓越创新中心 一种bxl基因或其编码蛋白的应用
CN114981405B (zh) * 2020-01-28 2024-09-06 东丽株式会社 木霉属丝状菌突变株
CN115552027A (zh) * 2020-05-19 2022-12-30 东丽株式会社 使用了玉米皮的蛋白质的制造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0731467A (ja) 1993-07-20 1995-02-03 Mitsui Toatsu Chem Inc 糸状菌の培養法
WO1997000964A1 (en) 1995-06-23 1997-01-09 Danisco Ingredients A/S (Danisco A/S) Novel beta-xylosidase, nucleotide sequence encoding it, and use thereof
CN1188510A (zh) * 1995-06-23 1998-07-22 丹尼斯科成分公司(丹尼斯科公司) 新的β-木糖苷酶和编码该酶的核苷酸序列以及该酶的用途
JP2009171885A (ja) * 2008-01-23 2009-08-06 Nippon Paper Industries Co Ltd セルロース含有物から糖を製造する方法
KR20100124787A (ko) * 2008-03-21 2010-11-29 다니스코 유에스 인크. 바이오매스의 가수분해를 향상시키기 위한 헤미셀룰라아제 강화 조성물
US8518684B2 (en) * 2008-11-18 2013-08-27 Novozymes, Inc. Methods and compositions for degrading cellulosic material
MX353237B (es) * 2009-09-23 2018-01-08 Danisco Us Inc Enzimas de glicosil hidrolasa novedosas y usos de las mismas.
US10138499B2 (en) 2009-12-23 2018-11-27 Danisco Us Inc. Methods for improving the efficiency of simultaneous saccharification and fermentation reactions
CA2808777C (en) 2010-08-25 2019-10-29 Danisco Us Inc. Filamentous fungi having an altered viscosity phenotype
JP2014150745A (ja) 2013-02-06 2014-08-25 Nagaoka Univ Of Technology トリコデルマ属に属する微生物の変異株および該変異株の使用
AU2014219823B2 (en) 2013-02-20 2017-07-20 Toray Industries, Inc. Sugar-solution production method
WO2014208493A1 (ja) * 2013-06-25 2014-12-31 東レ株式会社 糖液の製造方法
CN105473729B (zh) 2013-08-22 2019-05-14 东丽株式会社 糖液的制造方法
JP6508039B2 (ja) * 2013-12-27 2019-05-08 東レ株式会社 糖液の製造方法
EP3152315B1 (en) * 2014-06-06 2018-08-15 Novozymes A/S Enzyme compositions and uses thereof
US10041136B2 (en) 2014-07-10 2018-08-07 The United States Of America As Represented By The Secretary Of Agriculture Glycosyl hydrolase xylanases, compositions and methods of use for efficient hydrolysis and processing of xylan
WO2016068223A1 (ja) * 2014-10-31 2016-05-06 東レ株式会社 糖液およびキシロオリゴ糖の製造方法
WO2016100825A1 (en) * 2014-12-18 2016-06-23 Danisco Us Inc Engineered multifunctional enzymes and methods of use
CN109072222B (zh) * 2016-03-31 2022-05-06 东丽株式会社 具有突变型bxl1基因的木霉属真菌和使用该真菌制造低聚木糖和葡萄糖的制造方法
CA3019284A1 (en) * 2016-03-31 2017-10-05 Toray Industries, Inc. Method for producing xylo-oligosaccharide

Also Published As

Publication number Publication date
JPWO2017170917A1 (ja) 2018-04-05
EP3438262A4 (en) 2019-09-04
PH12018502082A1 (en) 2019-07-08
AU2017239832A1 (en) 2018-10-25
EP3974527A1 (en) 2022-03-30
EP3438262A1 (en) 2019-02-06
AU2017239832B2 (en) 2023-04-27
US11453899B2 (en) 2022-09-27
CN108779456A (zh) 2018-11-09
BR112018069854A2 (pt) 2019-01-29
WO2017170917A1 (ja) 2017-10-05
JP6939624B2 (ja) 2021-09-22
JP2018117620A (ja) 2018-08-02
CN108779456B (zh) 2022-04-05
US20200165647A1 (en) 2020-05-28
CA3019297A1 (en) 2017-10-05
EP3438262B1 (en) 2021-12-01

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