JP6305981B2 - 標的化治療薬 - Google Patents

標的化治療薬 Download PDF

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JP6305981B2
JP6305981B2 JP2015505991A JP2015505991A JP6305981B2 JP 6305981 B2 JP6305981 B2 JP 6305981B2 JP 2015505991 A JP2015505991 A JP 2015505991A JP 2015505991 A JP2015505991 A JP 2015505991A JP 6305981 B2 JP6305981 B2 JP 6305981B2
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sdc
trap
moiety
hsp90
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JP2015512953A (ja
JP2015512953A5 (https=
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チマナマダ，ディネーシュ，ユー．
イン，ウェイウェン
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マドリガル ファーマシューティカルズ，インコーポレーテッド
マドリガル ファーマシューティカルズ，インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2015505991A 2012-04-16 2013-04-16 標的化治療薬 Expired - Fee Related JP6305981B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261624639P 2012-04-16 2012-04-16
US61/624,639 2012-04-16
US13/843,771 2013-03-15
US13/843,771 US20140079636A1 (en) 2012-04-16 2013-03-15 Targeted therapeutics
PCT/US2013/036783 WO2013158644A2 (en) 2012-04-16 2013-04-16 Targeted therapeutics

Related Child Applications (1)

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JP2018040266A Division JP2018135332A (ja) 2012-04-16 2018-03-07 標的化治療薬

Publications (3)

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JP2015512953A JP2015512953A (ja) 2015-04-30
JP2015512953A5 JP2015512953A5 (https=) 2016-06-09
JP6305981B2 true JP6305981B2 (ja) 2018-04-04

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JP2015505991A Expired - Fee Related JP6305981B2 (ja) 2012-04-16 2013-04-16 標的化治療薬
JP2018040266A Pending JP2018135332A (ja) 2012-04-16 2018-03-07 標的化治療薬
JP2019161628A Expired - Fee Related JP6949911B2 (ja) 2012-04-16 2019-09-05 標的化治療薬
JP2021153930A Pending JP2022000452A (ja) 2012-04-16 2021-09-22 標的化治療薬

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JP2018040266A Pending JP2018135332A (ja) 2012-04-16 2018-03-07 標的化治療薬
JP2019161628A Expired - Fee Related JP6949911B2 (ja) 2012-04-16 2019-09-05 標的化治療薬
JP2021153930A Pending JP2022000452A (ja) 2012-04-16 2021-09-22 標的化治療薬

Country Status (10)

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US (4) US20140079636A1 (https=)
EP (2) EP2838909A4 (https=)
JP (4) JP6305981B2 (https=)
KR (4) KR102163906B1 (https=)
CN (2) CN110559446A (https=)
AU (4) AU2013249429B2 (https=)
CA (1) CA2870357A1 (https=)
HK (1) HK1207098A1 (https=)
IL (4) IL293316A (https=)
WO (1) WO2013158644A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018135332A (ja) * 2012-04-16 2018-08-30 マドリガル ファーマシューティカルズ，インコーポレーテッド 標的化治療薬
US11377447B2 (en) 2017-06-20 2022-07-05 Madrigal Pharmaceuticals, Inc. Targeted therapeutics
US11491145B2 (en) 2017-06-20 2022-11-08 Madrigal Pharmaceuticals, Inc. Combination therapies comprising targeted therapeutics

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100797283B1 (ko) 2001-08-27 2008-01-23 주식회사 포스코 코일 폭 감지 및 위치 조정 기능을 가진 코일 받침대
WO2010017545A2 (en) 2008-08-08 2010-02-11 Synta Pharamceuticals Corp. Triazole compounds that modulate hsp90 activity
WO2014025395A1 (en) 2012-08-06 2014-02-13 Duke University Compounds and methods for targeting hsp90
WO2014111815A2 (en) * 2013-01-18 2014-07-24 Cortendo Ab (Publ) Abiraterone and analogs thereof for the treatment of diseases associated with cortisol overproduction
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