JP6293732B2 - 噴霧化による肺サーファクタントの投与方法及びシステム - Google Patents

噴霧化による肺サーファクタントの投与方法及びシステム Download PDF

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JP6293732B2
JP6293732B2 JP2015506195A JP2015506195A JP6293732B2 JP 6293732 B2 JP6293732 B2 JP 6293732B2 JP 2015506195 A JP2015506195 A JP 2015506195A JP 2015506195 A JP2015506195 A JP 2015506195A JP 6293732 B2 JP6293732 B2 JP 6293732B2
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channel
catheter
surfactant
patient
pressure
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Expired - Fee Related
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Japanese (ja)
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JP2015514481A (ja
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デラッカ ラファエレ
デラッカ ラファエレ
ミレージ イラリア
ミレージ イラリア
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Chiesi Farmaceutici SpA
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Chiesi Farmaceutici SpA
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/03Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs
    • A61B5/036Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs by means introduced into body tracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057Pumps therefor
    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0475Tracheal tubes having openings in the tube
    • A61M16/0477Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
    • A61M16/0484Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids at the distal end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0486Multi-lumen tracheal tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/087Measuring breath flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/091Measuring volume of inspired or expired gases, e.g. to determine lung capacity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7242Details of waveform analysis using integration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0461Nasoendotracheal tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/105Filters
    • A61M16/106Filters in a path
    • A61M16/107Filters in a path in the inspiratory path
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M2025/004Multi-lumen catheters with stationary elements characterized by lumina being arranged circumferentially
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0468Liquids non-physiological
    • A61M2202/0488Surfactant, e.g. for the lung
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3348Pressure measurement using a water column
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/005Anatomical parts of the body used as an access side to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0618Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0625Mouth
    • A61M2210/065Throat; Pharynx
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2240/00Specially adapted for neonatal use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M25/003Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015506195A 2012-04-23 2013-04-12 噴霧化による肺サーファクタントの投与方法及びシステム Expired - Fee Related JP6293732B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12165234 2012-04-23
EP12165234.1 2012-04-23
PCT/EP2013/057744 WO2013160129A1 (en) 2012-04-23 2013-04-12 Method and system for the administration of a pulmonary surfactant by atomization

Publications (2)

Publication Number Publication Date
JP2015514481A JP2015514481A (ja) 2015-05-21
JP6293732B2 true JP6293732B2 (ja) 2018-03-14

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JP2015506195A Expired - Fee Related JP6293732B2 (ja) 2012-04-23 2013-04-12 噴霧化による肺サーファクタントの投与方法及びシステム

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Country Link
US (1) US10456538B2 (enExample)
EP (1) EP2841135B1 (enExample)
JP (1) JP6293732B2 (enExample)
KR (1) KR102051677B1 (enExample)
CN (1) CN104321103B (enExample)
AR (1) AR090811A1 (enExample)
AU (1) AU2013251865B2 (enExample)
BR (1) BR112014026212A8 (enExample)
CA (1) CA2870391A1 (enExample)
CL (1) CL2014002863A1 (enExample)
CO (1) CO7160044A2 (enExample)
EA (1) EA027030B1 (enExample)
ES (1) ES2616082T3 (enExample)
IL (1) IL235143A0 (enExample)
IN (1) IN2014DN09602A (enExample)
MA (1) MA37431B1 (enExample)
MX (1) MX351677B (enExample)
NZ (1) NZ701073A (enExample)
PE (1) PE20150604A1 (enExample)
PH (1) PH12014502321A1 (enExample)
SG (1) SG11201406628RA (enExample)
TN (1) TN2014000429A1 (enExample)
WO (1) WO2013160129A1 (enExample)
ZA (1) ZA201407557B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201609206A (zh) * 2013-10-22 2016-03-16 奇希製藥公司 藉由霧化投予肺部表面活性劑之改良方法及系統
WO2016089981A1 (en) * 2014-12-04 2016-06-09 Carefusion 2200, Inc. Breath-actuated nebulizer for medicine inhalation
WO2016109390A1 (en) 2014-12-29 2016-07-07 Ony Inc. Aerosol medication delivery system and method
ES2901761T3 (es) 2015-01-13 2022-03-23 Trudell Medical Int Interfaz respiratoria
EP3106090A1 (en) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. System for effective breath-synchronized delivery of medicament to the lungs
CN107666933A (zh) * 2015-04-22 2018-02-06 奇斯药制品公司 用于药物有效地呼吸同步递送到肺部的方法和系统
WO2016174098A1 (en) * 2015-04-28 2016-11-03 Chiesi Farmaceutici S.P.A. Device for facilitating the administration of a medicament to the lung by a catheter
WO2016173634A1 (en) 2015-04-28 2016-11-03 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
WO2017086939A1 (en) * 2015-11-17 2017-05-26 Flosure Technologies Llc Tracheal or endotracheal device having an integrated system for removing infectious secretions
EP3407844A4 (en) * 2016-01-29 2019-10-16 Qool Therapeutics, Inc. AEROSOLISATION OF STEM CELLS OR STEM CELL DERIVATIVES FOR PULMONARY ADMINISTRATION
KR101861078B1 (ko) * 2016-03-29 2018-05-28 (주)엘메카 네트워크를 통한 의료용 석션기의 관리 방법 및 이에 사용되는 관리 서버
WO2018019719A1 (en) 2016-07-28 2018-02-01 Chiesi Farmaceutici S.P.A Method and system for delivery of an aerosolized medicament
ES2892903T3 (es) * 2016-10-26 2022-02-07 Chiesi Farm Spa Dispositivo para facilitar la administración de un medicamento a los pulmones por medio de un catéter
AU2018240522B2 (en) * 2017-03-23 2023-07-06 Stamford Devices Ltd Aerosol delivery system and method
US11413407B2 (en) 2017-03-23 2022-08-16 Stamford Devices Ltd. Aerosol delivery device
EP3706773A2 (en) * 2017-11-10 2020-09-16 Defensin Therapeutics ApS Maturation of mucosal defense and gut/lung function in the preterm infant
MX2020011127A (es) * 2018-04-23 2021-01-15 Chiesi Farm Spa Combinacion terapeutica que comprende agente tensioactivo pulmonar y esteroide para la profilaxis de displasia broncopulmonar (bpd).
CN109745601B (zh) * 2019-01-11 2024-10-15 广州瑞普医疗科技有限公司 雾化过程监测方法、系统、计算机设备、存储介质及装置
US20230062996A1 (en) * 2019-10-11 2023-03-02 Rocket Science Health Corp. Intranasal drug delivery device, system, and process
US11771132B2 (en) 2020-08-27 2023-10-03 Rai Strategic Holdings, Inc. Atomization nozzle for aerosol delivery device
US20230364355A1 (en) * 2020-09-28 2023-11-16 Vectura Delivery Devices Limited Inhalation device
EP4272719A4 (en) * 2020-12-30 2024-11-20 Hexarhumancare Co., Ltd EXOSKELETON TYPE REHABILITATION ROBOT SYSTEM
WO2022154138A1 (ko) * 2021-01-13 2022-07-21 (주)앰틱스바이오 소화성 궤양 창상피복재 분무장치

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US692273A (en) * 1901-03-16 1902-02-04 Edward J Gulick Desk-support.
DE3206482C2 (de) * 1982-02-23 1984-03-15 Drägerwerk AG, 2400 Lübeck Beatmungsvorrichtung mit einer Einrichtung zur Sicherheitsüberwachung
US4813431A (en) * 1987-07-22 1989-03-21 David Brown Intrapulmonary pressure monitoring system
GB9307733D0 (en) * 1993-04-14 1993-06-02 Msa Britain Ltd Respiratory protective device
EP0758257B1 (en) * 1994-05-06 2000-02-23 Mark Brauner Apparatus for intrapulmonary therapy and drug administration
US5803078A (en) * 1994-05-06 1998-09-08 Brauner; Mark E. Methods and apparatus for intrapulmonary therapy and drug administration
ZA954936B (en) * 1994-06-17 1996-02-27 Trudell Medical Ltd Nebulizing catheter system and methods of use and manufacture
DE69814918T2 (de) * 1997-12-17 2004-03-11 Universidad De Sevilla Vorrichtung und verfahren zur erzeugung von aerosolen für arzneimittelverabreichung
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
US6315739B1 (en) * 1999-09-27 2001-11-13 Instrumentarium Corporation Apparatus and method for measuring the intratracheal pressure of an intubated patient
SE0203591D0 (sv) * 2002-12-04 2002-12-04 Siemens Elema Ab Förfarande för beredning av ett mediakament och en medicinsk anordning
US7267121B2 (en) * 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
KR101226995B1 (ko) * 2004-04-20 2013-01-28 노바르티스 아게 압력 보조식 호흡 장치용 에어로졸 전달 장치
DE102006006183A1 (de) * 2006-02-10 2007-08-16 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung für die Anwendung bei Frühgeborenen und Kleinkindern
CN2905088Y (zh) * 2006-04-10 2007-05-30 陈清甫 便携式雾化给药装置
US8303531B2 (en) * 2008-02-11 2012-11-06 Nordson Corporation Spray applicator with positionable spray tip
HRP20160258T1 (hr) * 2008-03-17 2016-04-22 Discovery Laboratories, Inc. Adapter za cijevni sustav ventilacije i proksimalni sustav za dovođenje aerosola
PL2110126T3 (pl) * 2008-04-18 2012-04-30 Novaliq Gmbh Zastosowanie do inhalacji i zakraplania semifluorowanych alkanów jako nośników substancji aktywnych w strefie wewnątrzpłucnej
DE102010025045B4 (de) * 2010-06-22 2016-11-03 Frank Jochum Vorrichtung zur Gabe von Surfactant
CN107293314B (zh) * 2016-03-31 2019-03-12 光宝电子(广州)有限公司 托盘刹车装置

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AR090811A1 (es) 2014-12-10
NZ701073A (en) 2016-04-29
CL2014002863A1 (es) 2015-04-10
KR102051677B1 (ko) 2019-12-03
EA201491812A1 (ru) 2015-02-27
BR112014026212A2 (pt) 2017-06-27
PH12014502321A1 (en) 2015-01-12
EP2841135A1 (en) 2015-03-04
CN104321103A (zh) 2015-01-28
MX351677B (es) 2017-10-25
JP2015514481A (ja) 2015-05-21
CO7160044A2 (es) 2015-01-15
CA2870391A1 (en) 2013-10-31
IN2014DN09602A (enExample) 2015-07-31
SG11201406628RA (en) 2014-11-27
MA20150421A1 (fr) 2015-11-30
WO2013160129A1 (en) 2013-10-31
HK1205474A1 (en) 2015-12-18
MX2014012368A (es) 2015-05-11
PE20150604A1 (es) 2015-06-07
ES2616082T3 (es) 2017-06-09
US20130333695A1 (en) 2013-12-19
ZA201407557B (en) 2016-08-31
CN104321103B (zh) 2017-04-26
KR20150004832A (ko) 2015-01-13
BR112014026212A8 (pt) 2019-12-24
AU2013251865A1 (en) 2014-11-06
EA027030B1 (ru) 2017-06-30
IL235143A0 (en) 2014-12-31
EP2841135B1 (en) 2016-12-14
TN2014000429A1 (en) 2016-03-30
MA37431B1 (fr) 2016-06-30
AU2013251865B2 (en) 2017-02-16

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