JP6289460B2 - 難聴を治療するためのニコチンアミドリボシド - Google Patents
難聴を治療するためのニコチンアミドリボシド Download PDFInfo
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- JP6289460B2 JP6289460B2 JP2015523158A JP2015523158A JP6289460B2 JP 6289460 B2 JP6289460 B2 JP 6289460B2 JP 2015523158 A JP2015523158 A JP 2015523158A JP 2015523158 A JP2015523158 A JP 2015523158A JP 6289460 B2 JP6289460 B2 JP 6289460B2
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- hearing loss
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- nicotinamide riboside
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201261672169P | 2012-07-16 | 2012-07-16 | |
| US61/672,169 | 2012-07-16 | ||
| PCT/US2013/050511 WO2014014828A1 (en) | 2012-07-16 | 2013-07-15 | Nicotinamide riboside to treat hearing loss |
Publications (3)
| Publication Number | Publication Date |
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| JP2015524408A JP2015524408A (ja) | 2015-08-24 |
| JP2015524408A5 JP2015524408A5 (https=) | 2016-09-08 |
| JP6289460B2 true JP6289460B2 (ja) | 2018-03-07 |
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| JP2015523158A Expired - Fee Related JP6289460B2 (ja) | 2012-07-16 | 2013-07-15 | 難聴を治療するためのニコチンアミドリボシド |
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| US (1) | US9861651B2 (https=) |
| EP (1) | EP2872128B1 (https=) |
| JP (1) | JP6289460B2 (https=) |
| ES (1) | ES2785303T3 (https=) |
| WO (1) | WO2014014828A1 (https=) |
Families Citing this family (21)
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|---|---|---|---|---|
| EP3369738B1 (en) | 2005-11-18 | 2020-05-20 | Cornell Research Foundation, Inc. | Method for making nicotinoyl ribosides and nicotinamide beta-riboside |
| AU2015270090A1 (en) | 2014-06-06 | 2016-12-22 | Glaxosmithkline Intellectual Property (No.2) Limited | Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof |
| US10323058B2 (en) | 2014-07-24 | 2019-06-18 | W. R. Grace & Co.-Conn. | Crystalline form of nicotinamide riboside |
| EP3268379B1 (en) | 2015-03-09 | 2023-11-01 | W.R. Grace & CO. - CONN. | Crystalline form of nicotinamide riboside |
| ES2882602T3 (es) | 2015-05-18 | 2021-12-02 | Sensorion | Azasetrón para usar en el tratamiento de la pérdida auditiva |
| WO2017011788A1 (en) | 2015-07-15 | 2017-01-19 | Cornell University | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives |
| US9855289B2 (en) | 2015-08-05 | 2018-01-02 | Metro International Biotech, Llc | Nicotinamide mononucleotide derivatives and their uses |
| GB2542881B (en) | 2015-10-02 | 2020-01-01 | Carr Andrew | Crystal forms of ß-nicotinamide mononucleotide |
| RS65379B1 (sr) | 2016-04-14 | 2024-04-30 | Sensorion | (+)-azasetron za upotrebu u lečenju poremećaja uha |
| CN110248650A (zh) * | 2016-10-31 | 2019-09-17 | 霍夫耳科研究所 | 用于增强突触发生和神经突发生的方法 |
| EP3538099B1 (en) | 2016-11-11 | 2026-04-22 | The Queen's University of Belfast | Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof |
| JP7136795B2 (ja) | 2016-11-29 | 2022-09-13 | ユニバーシティー オブ アイオワ リサーチ ファウンデーション | 母体の健康および／または子の健康を向上させるためのｎａｄ前駆体の使用 |
| US11071747B2 (en) | 2016-11-29 | 2021-07-27 | University Of Iowa Research Foundation | Use of NAD precursors for breast enhancement |
| US10961268B2 (en) | 2017-04-05 | 2021-03-30 | Cornell University | β-nicotinate ester nucleotides and process for preparing same |
| CN112020363A (zh) | 2017-12-22 | 2020-12-01 | 益力舒健康公司 | 烟酰胺核苷氯化物的结晶形式 |
| AU2019214858B2 (en) | 2018-01-30 | 2023-02-02 | Metro International Biotech, Llc | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof |
| US10618927B1 (en) | 2019-03-22 | 2020-04-14 | Metro International Biotech, Llc | Compositions and methods for modulation of nicotinamide adenine dinucleotide |
| US11939348B2 (en) | 2019-03-22 | 2024-03-26 | Metro International Biotech, Llc | Compositions comprising a phosphorus derivative of nicotinamide riboside and methods for modulation of nicotinamide adenine dinucleotide |
| BR112022000963A2 (pt) | 2019-07-19 | 2022-04-05 | Biosynth Ag | Método de fabricação de sais de nicotinamida ribofuranosídeo, sais de nicotinamida ribofuranosídeo como tal e usos dos mesmos |
| AU2022281388A1 (en) | 2021-05-27 | 2023-12-07 | Metro International Biotech, Llc | Crystalline solids of nicotinic acid mononucleotide and esters thereof and methods of making and use |
| CN121793959A (zh) | 2023-06-14 | 2026-04-03 | 可劳迈戴斯有限公司 | 静脉内配制品中的烟酰胺核苷及其衍生物与使用方法 |
Family Cites Families (5)
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| CH695593A5 (de) | 2002-12-17 | 2006-06-30 | Granite Trading Ltd | Vorsatzlinse. |
| US20060063802A1 (en) * | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| WO2007008548A2 (en) | 2005-07-07 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| KR20130097813A (ko) * | 2008-04-21 | 2013-09-03 | 오토노미, 인코포레이티드 | 귀 질환 및 병태를 치료하기 위한 귀 조제물 |
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- 2013-07-15 ES ES13820653T patent/ES2785303T3/es active Active
- 2013-07-15 US US14/414,924 patent/US9861651B2/en active Active
- 2013-07-15 JP JP2015523158A patent/JP6289460B2/ja not_active Expired - Fee Related
- 2013-07-15 WO PCT/US2013/050511 patent/WO2014014828A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015524408A (ja) | 2015-08-24 |
| WO2014014828A1 (en) | 2014-01-23 |
| US9861651B2 (en) | 2018-01-09 |
| EP2872128B1 (en) | 2020-02-19 |
| EP2872128A4 (en) | 2016-03-30 |
| EP2872128A1 (en) | 2015-05-20 |
| ES2785303T3 (es) | 2020-10-06 |
| US20150174148A1 (en) | 2015-06-25 |
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