JP6270717B2 - 磁性粒子のクラスタの検出 - Google Patents

磁性粒子のクラスタの検出 Download PDF

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Publication number
JP6270717B2
JP6270717B2 JP2014517993A JP2014517993A JP6270717B2 JP 6270717 B2 JP6270717 B2 JP 6270717B2 JP 2014517993 A JP2014517993 A JP 2014517993A JP 2014517993 A JP2014517993 A JP 2014517993A JP 6270717 B2 JP6270717 B2 JP 6270717B2
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magnetic particles
sample
clusters
magnetic field
sensor device
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JP2014517993A
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Japanese (ja)
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JP2014518389A (ja
JP2014518389A5 (enExample
Inventor
アンドレア ランゾーニ
アンドレア ランゾーニ
メノ ウィレム ヨセ プリンス
メノ ウィレム ヨセ プリンス
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1727—Magnetomodulation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers

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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2014517993A 2011-06-30 2012-06-18 磁性粒子のクラスタの検出 Active JP6270717B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11172070.2 2011-06-30
EP11172070A EP2541230A1 (en) 2011-06-30 2011-06-30 Detection of clusters of magnetic particles
PCT/IB2012/053051 WO2013001400A1 (en) 2011-06-30 2012-06-18 Detection of clusters of magnetic particles

Publications (3)

Publication Number Publication Date
JP2014518389A JP2014518389A (ja) 2014-07-28
JP2014518389A5 JP2014518389A5 (enExample) 2015-07-09
JP6270717B2 true JP6270717B2 (ja) 2018-01-31

Family

ID=44910028

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014517993A Active JP6270717B2 (ja) 2011-06-30 2012-06-18 磁性粒子のクラスタの検出

Country Status (5)

Country Link
US (1) US10036729B2 (enExample)
EP (2) EP2541230A1 (enExample)
JP (1) JP6270717B2 (enExample)
CN (1) CN103635788B (enExample)
WO (1) WO2013001400A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130051647A (ko) * 2011-11-10 2013-05-21 한국전자통신연구원 자성 입자를 이용한 바이오 물질의 분석 방법
US9863863B2 (en) 2011-11-14 2018-01-09 Koninklijke Philips N.V. Apparatus for cluster detection
JP7225656B2 (ja) * 2018-10-10 2023-02-21 凸版印刷株式会社 目的物質検出装置及び目的物質検出方法
CN116391126A (zh) 2020-08-07 2023-07-04 维塔生物科技公司 磁性分析物检测的动力学调节
TWI776251B (zh) * 2020-10-08 2022-09-01 中原大學 基於目標分子吸附之磁控量測系統
CN113515868B (zh) * 2021-08-04 2024-07-19 常熟理工学院 一种磁流变弹性体的链簇模型构建方法及性能估测方法
CN118818588B (zh) * 2024-07-12 2025-02-28 中国科学院近代物理研究所 高计数率twin-TPC的在线簇团重建方法、装置及设备

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62118255A (ja) * 1985-11-19 1987-05-29 Toshimitsu Musha 磁界を用いた免疫反応の検出法
CN1032399A (zh) * 1986-05-22 1989-04-12 尤尼利弗公司 免疫测定方法
US5252493A (en) * 1986-09-22 1993-10-12 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and apparatus therefor
JP3244509B2 (ja) 1991-01-16 2002-01-07 株式会社シノテスト 磁性粒子担体を用いた間接凝集反応法
TWI306153B (en) 2002-01-29 2009-02-11 Asahi Chemical Ind Biosensor, magnetic molecule measurement method, and measurement object measuring method
GB0410976D0 (en) 2004-05-17 2004-06-16 Randox Lab Ltd Magnetic particle detector system
JP5311445B2 (ja) * 2005-01-31 2013-10-09 コーニンクレッカ フィリップス エヌ ヴェ 高速かつ高感度バイオセンシング
JP2006247535A (ja) * 2005-03-10 2006-09-21 Toyo Univ 回転磁場を利用した反応促進方法
SE529474C2 (sv) 2006-04-19 2007-08-21 Imego Ab Detekteringsanordning och förfarande
US20100148765A1 (en) 2006-06-28 2010-06-17 Koninklijke Philips Electronics N.V. Magnetic sensor device with field generators and sensor elements
WO2008075285A1 (en) * 2006-12-19 2008-06-26 Koninklijke Philips Electronics N.V. Measuring agglutination parameters
CN101632018B (zh) 2007-02-23 2017-12-08 皇家飞利浦电子股份有限公司 用于感测磁性粒子的传感器设备和方法
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
WO2009007797A1 (en) 2007-07-09 2009-01-15 Koninklijke Philips Electronics N.V. Microelectronic sensor device with magnetic field generator and carrier
US20100277160A1 (en) 2007-12-18 2010-11-04 Koninklijke Philips Electronics N.V. Magnetic sensor device
US8486689B2 (en) * 2007-12-20 2013-07-16 Koninklijke Philips N.V. Microelectronic sensor device for the detection of target particles
JP5628784B2 (ja) * 2008-03-17 2014-11-19 コーニンクレッカ フィリップス エヌ ヴェ 磁性粒子によるアッセイ用カートリッジ
JP5685537B2 (ja) * 2008-09-05 2015-03-18 コーニンクレッカ フィリップス エヌ ヴェ クラスター・アッセイにおける改善した検出のための回転磁場
EP2389578B1 (en) * 2009-01-22 2013-03-06 Koninklijke Philips Electronics N.V. Mixed actuation protocol for a magnetic biosensor device
EP2492665A1 (en) 2009-10-19 2012-08-29 Tokyo Institute of Technology Biosensor using magnetic microparticles

Also Published As

Publication number Publication date
CN103635788A (zh) 2014-03-12
CN103635788B (zh) 2016-12-14
JP2014518389A (ja) 2014-07-28
US20140120632A1 (en) 2014-05-01
EP2726848A1 (en) 2014-05-07
WO2013001400A1 (en) 2013-01-03
US10036729B2 (en) 2018-07-31
EP2541230A1 (en) 2013-01-02
EP2726848B1 (en) 2016-04-13

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