BRPI0919987A8 - Dispositivo biosensor magnético e método para aplicar um campo magnético em uma superfície do sensor de um dispositivo biosensor magnético - Google Patents

Dispositivo biosensor magnético e método para aplicar um campo magnético em uma superfície do sensor de um dispositivo biosensor magnético

Info

Publication number
BRPI0919987A8
BRPI0919987A8 BRPI0919987A BRPI0919987A BRPI0919987A8 BR PI0919987 A8 BRPI0919987 A8 BR PI0919987A8 BR PI0919987 A BRPI0919987 A BR PI0919987A BR PI0919987 A BRPI0919987 A BR PI0919987A BR PI0919987 A8 BRPI0919987 A8 BR PI0919987A8
Authority
BR
Brazil
Prior art keywords
magnetic
magnetic field
applying
biosensor device
sensor surface
Prior art date
Application number
BRPI0919987A
Other languages
English (en)
Inventor
Van Zon Hans
Ovsyanko Mykhaylo
Original Assignee
Koninl Philips Electronics Nv
Koninklijke Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninl Philips Electronics Nv, Koninklijke Philips Nv filed Critical Koninl Philips Electronics Nv
Publication of BRPI0919987A2 publication Critical patent/BRPI0919987A2/pt
Publication of BRPI0919987A8 publication Critical patent/BRPI0919987A8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269—Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

DISPOSITIVO BIOSENSOR MAGNÉTICO E MÉTODO PARA APLICAR UM CAMPO MAGNÉTICO EM UMA SUPERFÍCIE DO SENSOR DE UM DISPOSITIVO BIOSENSOR MAGNÉTICO. A presente invenção apresenta um dispositivo biosensor magnético que compreende um cartucho do sensor para receber um ensaio a ser testado, uma unidade eletromagnética para produzir um campo magnético em uma superfície do sensor do cartucho do sensor, e um meio de detecção para detectar a presença de partículas magnéticas perto da superfície do sensor. A unidade eletromagnética é adaptada para produzir periodicamente um campo magnético que tem pelo menos uma primeira e uma segunda intensidades de campo magnético, em que a relação entre a proporção de tempo de aplicação da primeira intensidade de campo magnético e a proporção de tempo do período de aplicação da primeira e segunda intensidades de campo é variada durante a medição. A invenção apresenta adicionalmente um método para aplicar um campo magnético a uma superfície do sensor de um dispositivo biosensor magnético.
BRPI0919987A 2009-01-22 2009-04-09 Dispositivo biosensor magnético e método para aplicar um campo magnético em uma superfície do sensor de um dispositivo biosensor magnético BRPI0919987A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09151058 2009-01-22
PCT/IB2009/051496 WO2010084383A1 (en) 2009-01-22 2009-04-09 Mixed actuation protocol for a magnetic biosensor device

Publications (2)

Publication Number Publication Date
BRPI0919987A2 BRPI0919987A2 (pt) 2015-12-15
BRPI0919987A8 true BRPI0919987A8 (pt) 2016-08-30

Family

ID=41174796

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919987A BRPI0919987A8 (pt) 2009-01-22 2009-04-09 Dispositivo biosensor magnético e método para aplicar um campo magnético em uma superfície do sensor de um dispositivo biosensor magnético

Country Status (7)

Country Link
US (1) US8933694B2 (pt)
EP (1) EP2389578B1 (pt)
JP (1) JP5654487B2 (pt)
CN (1) CN102292634B (pt)
BR (1) BRPI0919987A8 (pt)
RU (1) RU2491540C2 (pt)
WO (1) WO2010084383A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011073866A1 (en) * 2009-12-18 2011-06-23 Koninklijke Philips Electronics N.V. Substance determining apparatus
US20130088221A1 (en) * 2010-06-22 2013-04-11 Koninklijke Philips Electronics N.V. Detection of magnetic particles and their clustering
US9207210B2 (en) * 2010-09-09 2015-12-08 Koninklijke Philips N.V. Method and a device for attracting magnetic particles to a surface
EP2541230A1 (en) * 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Detection of clusters of magnetic particles
WO2013064990A1 (en) * 2011-11-03 2013-05-10 Koninklijke Philips Electronics N.V. Detection of surface-bound magnetic particles
IN2014CN03614A (pt) * 2011-11-14 2015-10-09 Koninkl Philips Nv

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62118255A (ja) * 1985-11-19 1987-05-29 Toshimitsu Musha 磁界を用いた免疫反応の検出法
RU2166751C1 (ru) * 2000-03-09 2001-05-10 Никитин Петр Иванович Способ анализа смеси биологических и/или химических компонентов с использованием магнитных частиц и устройство для его осуществления
JP2002372490A (ja) * 2001-04-12 2002-12-26 Fuji Photo Film Co Ltd 全反射減衰を利用したセンサーおよび測定チップアセンブリ
CN100516879C (zh) 2002-01-29 2009-07-22 旭化成株式会社 生物传感器、用于磁性分子以及待测量目标的测量方法
US20080309329A1 (en) * 2003-07-30 2008-12-18 Koninklike Philips Electronics N.V. On-Chip Magnetic Sensor Device with Suppressed Cross-Talk
GB0410976D0 (en) 2004-05-17 2004-06-16 Randox Lab Ltd Magnetic particle detector system
US7482807B2 (en) 2004-09-28 2009-01-27 Koninklijke Philips Electronics N.V. Method of determining a spatial distribution of magnetic particles
JP2007271573A (ja) * 2006-03-31 2007-10-18 Osaka Gas Co Ltd 磁粉探傷装置および磁粉探傷方法
EP2018574A1 (en) * 2006-05-09 2009-01-28 Koninklijke Philips Electronics N.V. A magnetic sensor device for and a method of sensing magnetic particles
RU2482495C2 (ru) * 2006-10-12 2013-05-20 Конинклейке Филипс Электроникс Н.В. Быстрый биосенсор со слоем реагента
JP2010512534A (ja) * 2006-12-12 2010-04-22 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ ラベル粒子を検出するマイクロエレクトロニクスセンサデバイス
WO2008102218A1 (en) * 2007-02-23 2008-08-28 Koninklijke Philips Electronics N.V. A sensor device for and a method of sensing magnetic particles
EP3059583B1 (en) * 2007-03-06 2019-05-15 Koninklijke Philips N.V. An electromagnetic system for biosensors
WO2008139356A1 (en) * 2007-05-09 2008-11-20 Koninklijke Philips Electronics N. V. A cartridge for sample investigations
WO2009007797A1 (en) * 2007-07-09 2009-01-15 Koninklijke Philips Electronics N.V. Microelectronic sensor device with magnetic field generator and carrier

Also Published As

Publication number Publication date
CN102292634B (zh) 2016-08-03
RU2491540C2 (ru) 2013-08-27
JP2012515917A (ja) 2012-07-12
EP2389578A1 (en) 2011-11-30
JP5654487B2 (ja) 2015-01-14
EP2389578B1 (en) 2013-03-06
US20110279114A1 (en) 2011-11-17
RU2011134865A (ru) 2013-02-27
WO2010084383A1 (en) 2010-07-29
BRPI0919987A2 (pt) 2015-12-15
US8933694B2 (en) 2015-01-13
CN102292634A (zh) 2011-12-21

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B25G Requested change of headquarter approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]