JP6270717B2 - 磁性粒子のクラスタの検出 - Google Patents

磁性粒子のクラスタの検出 Download PDF

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Publication number
JP6270717B2
JP6270717B2 JP2014517993A JP2014517993A JP6270717B2 JP 6270717 B2 JP6270717 B2 JP 6270717B2 JP 2014517993 A JP2014517993 A JP 2014517993A JP 2014517993 A JP2014517993 A JP 2014517993A JP 6270717 B2 JP6270717 B2 JP 6270717B2
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magnetic particles
sample
clusters
magnetic field
sensor device
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Japanese (ja)
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JP2014518389A5 (cg-RX-API-DMAC7.html
JP2014518389A (ja
Inventor
アンドレア ランゾーニ
アンドレア ランゾーニ
メノ ウィレム ヨセ プリンス
メノ ウィレム ヨセ プリンス
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1727Magnetomodulation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers

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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2014517993A 2011-06-30 2012-06-18 磁性粒子のクラスタの検出 Active JP6270717B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11172070.2 2011-06-30
EP11172070A EP2541230A1 (en) 2011-06-30 2011-06-30 Detection of clusters of magnetic particles
PCT/IB2012/053051 WO2013001400A1 (en) 2011-06-30 2012-06-18 Detection of clusters of magnetic particles

Publications (3)

Publication Number Publication Date
JP2014518389A JP2014518389A (ja) 2014-07-28
JP2014518389A5 JP2014518389A5 (cg-RX-API-DMAC7.html) 2015-07-09
JP6270717B2 true JP6270717B2 (ja) 2018-01-31

Family

ID=44910028

Family Applications (1)

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JP2014517993A Active JP6270717B2 (ja) 2011-06-30 2012-06-18 磁性粒子のクラスタの検出

Country Status (5)

Country Link
US (1) US10036729B2 (cg-RX-API-DMAC7.html)
EP (2) EP2541230A1 (cg-RX-API-DMAC7.html)
JP (1) JP6270717B2 (cg-RX-API-DMAC7.html)
CN (1) CN103635788B (cg-RX-API-DMAC7.html)
WO (1) WO2013001400A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130051647A (ko) * 2011-11-10 2013-05-21 한국전자통신연구원 자성 입자를 이용한 바이오 물질의 분석 방법
US9863863B2 (en) 2011-11-14 2018-01-09 Koninklijke Philips N.V. Apparatus for cluster detection
JP7225656B2 (ja) * 2018-10-10 2023-02-21 凸版印刷株式会社 目的物質検出装置及び目的物質検出方法
TWI776251B (zh) * 2020-10-08 2022-09-01 中原大學 基於目標分子吸附之磁控量測系統
CN113515868B (zh) * 2021-08-04 2024-07-19 常熟理工学院 一种磁流变弹性体的链簇模型构建方法及性能估测方法
CN118818588B (zh) * 2024-07-12 2025-02-28 中国科学院近代物理研究所 高计数率twin-TPC的在线簇团重建方法、装置及设备

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62118255A (ja) * 1985-11-19 1987-05-29 Toshimitsu Musha 磁界を用いた免疫反応の検出法
CN1032399A (zh) * 1986-05-22 1989-04-12 尤尼利弗公司 免疫测定方法
EP0287665B1 (en) * 1986-09-22 1996-07-31 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and apparatus therefor
JP3244509B2 (ja) * 1991-01-16 2002-01-07 株式会社シノテスト 磁性粒子担体を用いた間接凝集反応法
WO2003067258A1 (fr) 2002-01-29 2003-08-14 Asahi Kasei Kabushiki Kaisha Biocapteur, procede de mesure de molecules magnetiques et procede de mesure de l'objet mesure
GB0410976D0 (en) 2004-05-17 2004-06-16 Randox Lab Ltd Magnetic particle detector system
RU2415433C2 (ru) * 2005-01-31 2011-03-27 Конинклейке Филипс Электроникс Н.В. Быстрое и чувствительное измерение биоинформации
JP2006247535A (ja) * 2005-03-10 2006-09-21 Toyo Univ 回転磁場を利用した反応促進方法
SE529474C2 (sv) 2006-04-19 2007-08-21 Imego Ab Detekteringsanordning och förfarande
WO2008001263A2 (en) 2006-06-28 2008-01-03 Koninklijke Philips Electronics N. V. Magnetic sensor device with field generators and sensor elements
RU2460058C2 (ru) * 2006-12-19 2012-08-27 Конинклейке Филипс Электроникс Н.В. Измерение параметров агглютинации
WO2008102218A1 (en) 2007-02-23 2008-08-28 Koninklijke Philips Electronics N.V. A sensor device for and a method of sensing magnetic particles
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
US20100188076A1 (en) 2007-07-09 2010-07-29 Koninklijke Philips Electronics N.V. Microelectronic sensor device with magnetic field generator and carrier
WO2009081309A2 (en) 2007-12-18 2009-07-02 Koninklijke Philips Electronics N. V. A magnetic sensor device
JP2011508199A (ja) * 2007-12-20 2011-03-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 標的粒子を検出するためのマイクロエレクトロニクスセンサデバイス
WO2009115951A1 (en) * 2008-03-17 2009-09-24 Koninklijke Philips Electronics N.V. Cartridge for assays with magnetic particles
BRPI0913469A2 (pt) * 2008-09-05 2015-12-22 Koninkl Philips Electronics Nv método para a realização de um ensaio de aglomerado, aparelho para a realização de um ensaio de aglomerado, uso de um método e uso de um aparelho
US8933694B2 (en) * 2009-01-22 2015-01-13 Koninklijkle Philips N.V. Mixed actuation protocol for a magnetic biosensor device
US20120251392A1 (en) 2009-10-19 2012-10-04 Tokyo Institute Of Technology Biosensor Using Magnetic Microparticles

Also Published As

Publication number Publication date
US10036729B2 (en) 2018-07-31
EP2541230A1 (en) 2013-01-02
US20140120632A1 (en) 2014-05-01
EP2726848B1 (en) 2016-04-13
CN103635788A (zh) 2014-03-12
JP2014518389A (ja) 2014-07-28
EP2726848A1 (en) 2014-05-07
CN103635788B (zh) 2016-12-14
WO2013001400A1 (en) 2013-01-03

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