JP6267239B2 - 極めて低粘度の新規エステル化セルロースエーテル - Google Patents

極めて低粘度の新規エステル化セルロースエーテル Download PDF

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Publication number
JP6267239B2
JP6267239B2 JP2015560340A JP2015560340A JP6267239B2 JP 6267239 B2 JP6267239 B2 JP 6267239B2 JP 2015560340 A JP2015560340 A JP 2015560340A JP 2015560340 A JP2015560340 A JP 2015560340A JP 6267239 B2 JP6267239 B2 JP 6267239B2
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Japan
Prior art keywords
cellulose ether
esterified cellulose
viscosity
esterified
solution
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Expired - Fee Related
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JP2015560340A
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English (en)
Japanese (ja)
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JP2016516835A5 (cg-RX-API-DMAC7.html
JP2016516835A (ja
Inventor
オリヴァー・ピーターマン
ロバート・ビー・アッペル
マインオルフ・ブラックハーゲン
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Dow Global Technologies LLC
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Dow Global Technologies LLC
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B13/00—Preparation of cellulose ether-esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2015560340A 2013-03-07 2014-02-28 極めて低粘度の新規エステル化セルロースエーテル Expired - Fee Related JP6267239B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361774161P 2013-03-07 2013-03-07
US61/774,161 2013-03-07
PCT/US2014/019266 WO2014137778A1 (en) 2013-03-07 2014-02-28 Novel esterified cellulose ethers of very low viscosity

Publications (3)

Publication Number Publication Date
JP2016516835A JP2016516835A (ja) 2016-06-09
JP2016516835A5 JP2016516835A5 (cg-RX-API-DMAC7.html) 2016-11-04
JP6267239B2 true JP6267239B2 (ja) 2018-01-24

Family

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Family Applications (1)

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JP2015560340A Expired - Fee Related JP6267239B2 (ja) 2013-03-07 2014-02-28 極めて低粘度の新規エステル化セルロースエーテル

Country Status (7)

Country Link
US (1) US9617351B2 (cg-RX-API-DMAC7.html)
EP (1) EP2964204B1 (cg-RX-API-DMAC7.html)
JP (1) JP6267239B2 (cg-RX-API-DMAC7.html)
KR (1) KR101661952B1 (cg-RX-API-DMAC7.html)
CN (1) CN105025887B (cg-RX-API-DMAC7.html)
BR (1) BR112015015846A2 (cg-RX-API-DMAC7.html)
WO (1) WO2014137778A1 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6371482B2 (ja) * 2015-03-16 2018-08-08 ダウ グローバル テクノロジーズ エルエルシー エステル化セルロースエーテルの水溶液
WO2016148975A1 (en) * 2015-03-16 2016-09-22 Dow Global Technologies Llc A process for fractionating an esterified cellulose ether
BR112017018232A2 (pt) 2015-03-16 2018-04-17 Dow Global Technologies Llc éteres de celulose esterificados solúveis em água
JP6356922B2 (ja) * 2015-03-16 2018-07-11 ダウ グローバル テクノロジーズ エルエルシー 低い中和度を有する水溶性エステル化セルロースエーテル
KR20170128355A (ko) * 2015-03-16 2017-11-22 다우 글로벌 테크놀로지스 엘엘씨 에스테르화 셀룰로오스 에테르의 겔화
JP6295380B2 (ja) * 2015-03-16 2018-03-14 ダウ グローバル テクノロジーズ エルエルシー 脂肪族カルボン酸の存在下でエステル化セルロースエーテルを調製するためのプロセス
JP6564148B2 (ja) 2016-05-25 2019-08-21 ダウ グローバル テクノロジーズ エルエルシー セルロースエーテルアセテートの水溶液
KR102490265B1 (ko) * 2016-11-02 2023-01-20 신에쓰 가가꾸 고교 가부시끼가이샤 히프로멜로오스아세트산에스테르숙신산에스테르 및 제조 방법
KR20190125334A (ko) 2017-03-17 2019-11-06 다우 글로벌 테크놀로지스 엘엘씨 반응 생성 혼합물로부터 에스테르화 셀룰로스 에테르를 회수하는 공정
MX2019010207A (es) 2017-03-17 2019-10-09 Dow Global Technologies Llc Proceso para recuperar un eter de celulosa esterificado a partir de una mezcla de producto de reaccion.
WO2018170083A1 (en) 2017-03-17 2018-09-20 Dow Global Technologies Llc Process for recovering an esterified cellulose ether from a reaction product mixture

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4819231B1 (cg-RX-API-DMAC7.html) 1970-03-06 1973-06-12
US4226981A (en) * 1977-09-28 1980-10-07 Shin-Etsu Chemical Co., Ltd. Ether-ester derivatives of cellulose and their applications
US4365060A (en) 1979-04-28 1982-12-21 Shin-Etsu Chemical Co. Ltd. Enterosoluble capsules
JPS59167521A (ja) * 1983-03-14 1984-09-21 Shin Etsu Chem Co Ltd 腸溶性コ−テイング剤組成物
JPS6281402A (ja) 1985-10-07 1987-04-14 Shin Etsu Chem Co Ltd セルロ−スエ−テル酸性ジカルボン酸エステルの製造方法
JP3149122B2 (ja) 1994-11-07 2001-03-26 信越化学工業株式会社 固形腸溶製剤のコーティング用基剤
JPH10167959A (ja) * 1996-12-04 1998-06-23 Zensei Yakuhin Kogyo Kk ジクロフェナクナトリウムの徐放性カプセル製剤
EP0872233A1 (en) 1997-04-14 1998-10-21 Janssen Pharmaceutica N.V. Antiretroviral compositions with improved bioavailability
DK0901786T3 (da) 1997-08-11 2007-10-08 Pfizer Prod Inc Faste farmaceutiske dispersioner med foröget biotilgængelighed
KR100387126B1 (ko) * 2001-04-19 2003-06-12 삼성정밀화학 주식회사 히드록시프로필메틸 셀룰로오스 프탈레이트의 분리정제방법
DE10141680B4 (de) * 2001-08-25 2004-02-26 Clariant Gmbh Verfahren zur Herstellung niederviskoser Celluloseether durch sauer-oxidativen Abbau von gemahlenen und getrockneten Celluloseethern
IL165043A0 (en) 2002-05-17 2005-12-18 Tibotec Pharm Ltd broadspectrum substituted benzisoxazole sulfonamide hiv protease inhibitors
ATE442130T1 (de) 2002-08-12 2009-09-15 Bend Res Inc Arzneizubereitungen bestehend aus arzneimitteln in halb-geordneter form und polymeren
DE602005010074D1 (de) * 2004-05-28 2008-11-13 Pfizer Prod Inc Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymer
WO2009070744A1 (en) 2007-11-28 2009-06-04 Sequoia Pharmaceuticals, Inc. Compositions and methods for inhibiting cytochrome p450 2d6
US8920554B2 (en) * 2007-11-09 2014-12-30 Dow Global Technologies Llc Method for preparing very low viscosity cellulose ether and product
KR101598009B1 (ko) 2007-11-09 2016-02-29 다우 글로벌 테크놀로지스 엘엘씨 셀룰로스 에테르 피복 조성물 및 방법
JP5322740B2 (ja) * 2009-04-01 2013-10-23 国立大学法人東京農工大学 有害生物防除方法
WO2011159626A1 (en) * 2010-06-14 2011-12-22 Bend Research, Inc. Hydroxypropyl methyl cellulose acetate succinate with enhanced acetate and succinate substitution
US20120251588A1 (en) * 2011-03-30 2012-10-04 Miyuki Fukasawa Coating Composition, Solid Preparation Coated Therewith, and Method for Preparing Solid Preparation
EP2831121B1 (en) 2012-03-27 2018-10-10 Dow Global Technologies LLC A process of preparing an ester of a cellulose ether
JP6133969B2 (ja) * 2012-04-11 2017-05-24 ダウ グローバル テクノロジーズ エルエルシー 特定の置換基分布を有するエステル化セルロースエーテル
MX2015002427A (es) 2012-08-24 2015-06-22 Dow Global Technologies Llc Eteres de celulosa esterificados parcialmente entrelazados.
JP6224712B2 (ja) 2012-08-24 2017-11-01 ダウ グローバル テクノロジーズ エルエルシー 高分子量および均一性の新規エステル化セルロースエーテル
KR102138544B1 (ko) * 2012-08-24 2020-07-28 다우 글로벌 테크놀로지스 엘엘씨 신규한 하이드록시알킬 메틸 셀룰로즈 아세테이트 석시네이트

Also Published As

Publication number Publication date
EP2964204B1 (en) 2017-01-04
WO2014137778A1 (en) 2014-09-12
US20150376299A1 (en) 2015-12-31
CN105025887A (zh) 2015-11-04
KR101661952B1 (ko) 2016-10-04
KR20150119472A (ko) 2015-10-23
BR112015015846A2 (pt) 2017-07-11
EP2964204A1 (en) 2016-01-13
CN105025887B (zh) 2017-07-28
JP2016516835A (ja) 2016-06-09
US9617351B2 (en) 2017-04-11

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