JP6253580B2 - 自己免疫および炎症性疾患の治療のための方法および組成物 - Google Patents

自己免疫および炎症性疾患の治療のための方法および組成物 Download PDF

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JP6253580B2
JP6253580B2 JP2014525142A JP2014525142A JP6253580B2 JP 6253580 B2 JP6253580 B2 JP 6253580B2 JP 2014525142 A JP2014525142 A JP 2014525142A JP 2014525142 A JP2014525142 A JP 2014525142A JP 6253580 B2 JP6253580 B2 JP 6253580B2
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rhob
antibody
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amino acids
inflammatory
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JP2014529590A (ja
JP2014529590A5 (enExample
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リサ・ローリー−クライントップ
ローラ・マンディック−ナヤック
ジョージ・シー・プレンダーギャスト
ジェイムズ・ドゥハダウェイ
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ランケナー インスティテュート フォー メディカル リサーチ
ランケナー インスティテュート フォー メディカル リサーチ
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response

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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
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  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2014525142A 2011-08-10 2012-08-09 自己免疫および炎症性疾患の治療のための方法および組成物 Expired - Fee Related JP6253580B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161522009P 2011-08-10 2011-08-10
US61/522,009 2011-08-10
PCT/US2012/050146 WO2013023059A2 (en) 2011-08-10 2012-08-09 Methods and compositions for the treatment of autoimmune and inflammatory diseases

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JP2014529590A JP2014529590A (ja) 2014-11-13
JP2014529590A5 JP2014529590A5 (enExample) 2015-09-24
JP6253580B2 true JP6253580B2 (ja) 2017-12-27

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JP2014525142A Expired - Fee Related JP6253580B2 (ja) 2011-08-10 2012-08-09 自己免疫および炎症性疾患の治療のための方法および組成物

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US (3) US9879092B2 (enExample)
EP (1) EP2741771B1 (enExample)
JP (1) JP6253580B2 (enExample)
KR (2) KR102221068B1 (enExample)
CN (1) CN104114184B (enExample)
AU (1) AU2012294342B2 (enExample)
CA (1) CA2844668C (enExample)
ES (1) ES2813415T3 (enExample)
RU (1) RU2639540C2 (enExample)
WO (1) WO2013023059A2 (enExample)

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US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
WO2013023059A2 (en) 2011-08-10 2013-02-14 Lankenau Institute For Medical Research Methods and compositions for the treatment of autoimmune and inflammatory diseases
CA2884704C (en) 2012-09-07 2023-04-04 Randolph J. Noelle Vista modulators for diagnosis and treatment of cancer
US10273301B2 (en) 2013-12-24 2019-04-30 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
AU2015243261B2 (en) * 2014-04-10 2020-06-25 Lankenau Institute For Medical Research Methods and compositions for the treatment of ocular diseases and disorders
EP3722314A1 (en) 2015-06-24 2020-10-14 Janssen Pharmaceutica NV Anti-vista antibodies and fragments
US10899836B2 (en) 2016-02-12 2021-01-26 Janssen Pharmaceutica Nv Method of identifying anti-VISTA antibodies
PE20190115A1 (es) 2016-04-15 2019-01-16 Immunext Inc Anticuerpos vista antihumanos y su uso
WO2018213331A1 (en) * 2017-05-16 2018-11-22 Lankenau Institute For Medical Research Compositions comprising ligands to rhob protein and the uses thereof
KR102276941B1 (ko) * 2018-07-03 2021-07-14 서울대학교산학협력단 류마티스 관절염 치료용 펩티드 및 그의 용도

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AU4116793A (en) * 1992-04-24 1993-11-29 Board Of Regents, The University Of Texas System Recombinant production of immunoglobulin-like domains in prokaryotic cells
EP1027042A4 (en) 1997-09-29 2004-08-18 Bristol Myers Squibb Co FARNESYL PROTEIN TRANSFERASE INHIBITORS
US6458783B1 (en) * 1997-09-29 2002-10-01 Bristol-Myers Squibb Company Non-imidazole benzodiazepine inhibitors of farnesyl protein transferase
US5962672A (en) * 1998-09-18 1999-10-05 Isis Pharmaceuticals Inc. Antisense modulation of RhoB expression
US20050032733A1 (en) 2001-05-18 2005-02-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
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WO2005017160A2 (en) * 2003-08-13 2005-02-24 Children's Hospital Medical Center Mobilization of hematopoietic cells
JP4967137B2 (ja) * 2005-04-18 2012-07-04 国立大学法人浜松医科大学 癌治療用組成物
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RU2489166C2 (ru) * 2006-04-09 2013-08-10 Джинентех, Инк. Применение антитела для лечения аутоиммунных заболеваний у пациента с неадекватным ответом на ингибитор tnf-альфа
JP5354634B2 (ja) * 2007-01-25 2013-11-27 国立大学法人大阪大学 ヒトａｂｈ８タンパク質、それをコードする遺伝子、およびこれらの治療的又は診断的用途
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Publication number Publication date
KR20200042013A (ko) 2020-04-22
KR102101478B1 (ko) 2020-04-16
JP2014529590A (ja) 2014-11-13
EP2741771B1 (en) 2020-04-29
EP2741771A2 (en) 2014-06-18
RU2639540C2 (ru) 2017-12-21
EP2741771A4 (en) 2015-04-15
AU2012294342A1 (en) 2014-03-06
WO2013023059A2 (en) 2013-02-14
ES2813415T3 (es) 2021-03-23
US12545744B2 (en) 2026-02-10
US20140227279A1 (en) 2014-08-14
US20210040230A1 (en) 2021-02-11
KR20140067027A (ko) 2014-06-03
RU2014106933A (ru) 2015-09-20
CN104114184B (zh) 2017-04-19
US9879092B2 (en) 2018-01-30
AU2012294342B2 (en) 2017-07-27
CN104114184A (zh) 2014-10-22
CA2844668A1 (en) 2013-02-14
US20180094076A1 (en) 2018-04-05
WO2013023059A3 (en) 2013-04-04
CA2844668C (en) 2021-03-09
KR102221068B1 (ko) 2021-02-25

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