JP6249447B2 - 癌治療用ペプチド剤 - Google Patents

癌治療用ペプチド剤 Download PDF

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Publication number
JP6249447B2
JP6249447B2 JP2014553578A JP2014553578A JP6249447B2 JP 6249447 B2 JP6249447 B2 JP 6249447B2 JP 2014553578 A JP2014553578 A JP 2014553578A JP 2014553578 A JP2014553578 A JP 2014553578A JP 6249447 B2 JP6249447 B2 JP 6249447B2
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Prior art keywords
peptide
seq
cell
cancer
amino acid
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Expired - Fee Related
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JP2014553578A
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English (en)
Japanese (ja)
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JP2015510393A5 (enExample
JP2015510393A (ja
Inventor
マイケル・ヴァレンティン・アグレス
Original Assignee
インターケー・ペプチド・セラピューティクス・リミテッド
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Priority claimed from AU2012900259A external-priority patent/AU2012900259A0/en
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Publication of JP2015510393A publication Critical patent/JP2015510393A/ja
Publication of JP2015510393A5 publication Critical patent/JP2015510393A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/005Enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546Integrin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2014553578A 2012-01-24 2013-01-24 癌治療用ペプチド剤 Expired - Fee Related JP6249447B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2012900259A AU2012900259A0 (en) 2012-01-24 Agents for use in cancer therapy
AU2012900259 2012-01-24
AU2012904368 2012-10-06
AU2012904368A AU2012904368A0 (en) 2012-10-06 Anti-cancer peptides
PCT/AU2013/000045 WO2013110120A1 (en) 2012-01-24 2013-01-24 Peptide agents for cancer therapy

Publications (3)

Publication Number Publication Date
JP2015510393A JP2015510393A (ja) 2015-04-09
JP2015510393A5 JP2015510393A5 (enExample) 2016-03-17
JP6249447B2 true JP6249447B2 (ja) 2017-12-20

Family

ID=48872819

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014553578A Expired - Fee Related JP6249447B2 (ja) 2012-01-24 2013-01-24 癌治療用ペプチド剤

Country Status (7)

Country Link
US (1) US9403877B2 (enExample)
EP (1) EP2807180B1 (enExample)
JP (1) JP6249447B2 (enExample)
CN (1) CN104271590B (enExample)
AU (1) AU2013202137B2 (enExample)
CA (1) CA2862485C (enExample)
WO (1) WO2013110120A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101644982B1 (ko) * 2015-07-23 2016-08-02 주식회사 엔솔바이오사이언스 신규 펩타이드 및 그 용도
CN105294839A (zh) * 2015-10-28 2016-02-03 上海大学 对新生血管形成有阻断功能的多肽化合物及其应用
CN106146620A (zh) * 2016-07-09 2016-11-23 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN106167513A (zh) * 2016-07-09 2016-11-30 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN106084012A (zh) * 2016-07-09 2016-11-09 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN105936643A (zh) * 2016-07-09 2016-09-14 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN105936642A (zh) * 2016-07-09 2016-09-14 青岛大学 具有抑制癌细胞生长活性的肽及其应用
GB201706472D0 (en) * 2017-04-24 2017-06-07 Cancer Res Tech Ltd Tumour-targeting peptide variants
CN111094324B (zh) * 2018-03-14 2023-10-10 武汉博威德生物技术有限公司 一种溶瘤病毒、合成dna序列及其应用
KR20210021984A (ko) * 2018-05-15 2021-03-02 인터크 펩타이드 테라퓨틱스 리미티드 펩타이드 활성화 제제
US12134663B2 (en) * 2018-05-15 2024-11-05 Interk Peptide Therapeutics Limited Cationic peptides for activating Lck
KR20210097729A (ko) * 2018-11-30 2021-08-09 인터크 펩타이드 테라퓨틱스 리미티드 피부 병태를 개선하기 위한 폴리펩타이드 및 방법
CN110893236A (zh) * 2019-10-09 2020-03-20 中山大学 溶酶体靶向的抗体药物偶联物及其应用
CN112646018B (zh) * 2021-01-25 2023-04-28 井冈山大学 一种抑制肿瘤细胞增殖和转移的生物活性肽及其应用
CN117979985A (zh) * 2021-08-20 2024-05-03 英特肽治疗有限公司 用于治疗包括与癌症和癌症疗法相关的自身免疫在内的自身免疫的组合物和方法

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US20030162956A1 (en) 1997-04-07 2003-08-28 Human Genome Sciences, Inc. Leukocyte regulatory factors 1 and 2
ATE385503T1 (de) 1999-06-28 2008-02-15 Inter K Pty Ltd Verfahren zur modulierung von integrin- vermittelter zellaktivitaet und hierfuer geeignete reagenzien
MXPA02012198A (es) 2000-06-09 2004-08-19 Teni Boulikas Encapsulacion de polinucleotidos y drogas en liposomas objetivos.
US6696546B1 (en) * 2000-11-06 2004-02-24 The Trustees Of Columbia University In The City Of New York Peptide that kills growing but not stationary cells
AUPR230500A0 (en) * 2000-12-22 2001-01-25 University Of Newcastle Research Associates Limited, The A method of modulating map kinase mediated cellular activity and agents useful in same
WO2002053726A2 (en) * 2001-01-02 2002-07-11 Hybrigenics Protein-protein interactions in adipocyte cells
US20030194798A1 (en) 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
PT2302063T (pt) 2001-10-15 2016-07-28 Engeneic Molecular Delivery Pty Ltd Minicélulas intactas, como vetores para a transferência de adn e terapêutica genética in vitro e in vivo
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Also Published As

Publication number Publication date
EP2807180B1 (en) 2018-03-28
CN104271590A (zh) 2015-01-07
US9403877B2 (en) 2016-08-02
WO2013110120A1 (en) 2013-08-01
AU2013202137B2 (en) 2015-09-10
EP2807180A1 (en) 2014-12-03
CA2862485C (en) 2021-05-11
CA2862485A1 (en) 2013-08-01
JP2015510393A (ja) 2015-04-09
US20150110744A1 (en) 2015-04-23
EP2807180A4 (en) 2016-01-06
CN104271590B (zh) 2018-06-05

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