AU2013202137B2 - Peptide agents for cancer therapy - Google Patents

Peptide agents for cancer therapy Download PDF

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Publication number
AU2013202137B2
AU2013202137B2 AU2013202137A AU2013202137A AU2013202137B2 AU 2013202137 B2 AU2013202137 B2 AU 2013202137B2 AU 2013202137 A AU2013202137 A AU 2013202137A AU 2013202137 A AU2013202137 A AU 2013202137A AU 2013202137 B2 AU2013202137 B2 AU 2013202137B2
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AU
Australia
Prior art keywords
peptide
amino acid
cell
seq
cancer
Prior art date
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Active
Application number
AU2013202137A
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English (en)
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AU2013202137A1 (en
Inventor
Michael Valentine Agrez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
InterK Peptide Therapeutics Ltd
Original Assignee
Inter K Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012900259A external-priority patent/AU2012900259A0/en
Application filed by Inter K Pty Ltd filed Critical Inter K Pty Ltd
Priority to AU2013202137A priority Critical patent/AU2013202137B2/en
Publication of AU2013202137A1 publication Critical patent/AU2013202137A1/en
Application granted granted Critical
Publication of AU2013202137B2 publication Critical patent/AU2013202137B2/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/005Enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546Integrin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2013202137A 2012-01-24 2013-01-24 Peptide agents for cancer therapy Active AU2013202137B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013202137A AU2013202137B2 (en) 2012-01-24 2013-01-24 Peptide agents for cancer therapy

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
AU2012900259A AU2012900259A0 (en) 2012-01-24 Agents for use in cancer therapy
AU2012900259 2012-01-24
AU2012904368 2012-10-06
AU2012904368A AU2012904368A0 (en) 2012-10-06 Anti-cancer peptides
PCT/AU2013/000045 WO2013110120A1 (en) 2012-01-24 2013-01-24 Peptide agents for cancer therapy
AU2013202137A AU2013202137B2 (en) 2012-01-24 2013-01-24 Peptide agents for cancer therapy

Publications (2)

Publication Number Publication Date
AU2013202137A1 AU2013202137A1 (en) 2013-08-08
AU2013202137B2 true AU2013202137B2 (en) 2015-09-10

Family

ID=48872819

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013202137A Active AU2013202137B2 (en) 2012-01-24 2013-01-24 Peptide agents for cancer therapy

Country Status (7)

Country Link
US (1) US9403877B2 (enExample)
EP (1) EP2807180B1 (enExample)
JP (1) JP6249447B2 (enExample)
CN (1) CN104271590B (enExample)
AU (1) AU2013202137B2 (enExample)
CA (1) CA2862485C (enExample)
WO (1) WO2013110120A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
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KR101644982B1 (ko) * 2015-07-23 2016-08-02 주식회사 엔솔바이오사이언스 신규 펩타이드 및 그 용도
CN105294839A (zh) * 2015-10-28 2016-02-03 上海大学 对新生血管形成有阻断功能的多肽化合物及其应用
CN105936643A (zh) * 2016-07-09 2016-09-14 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN106146620A (zh) * 2016-07-09 2016-11-23 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN106167513A (zh) * 2016-07-09 2016-11-30 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN106084012A (zh) * 2016-07-09 2016-11-09 青岛大学 具有抑制癌细胞生长活性的肽及其应用
CN105936642A (zh) * 2016-07-09 2016-09-14 青岛大学 具有抑制癌细胞生长活性的肽及其应用
GB201706472D0 (en) * 2017-04-24 2017-06-07 Cancer Res Tech Ltd Tumour-targeting peptide variants
WO2019174610A1 (zh) * 2018-03-14 2019-09-19 蔡立刚 一种溶瘤病毒、合成dna序列及其应用
AU2019268411B2 (en) * 2018-05-15 2024-03-14 Interk Peptide Therapeutics Limited Activating agents
KR20210021984A (ko) 2018-05-15 2021-03-02 인터크 펩타이드 테라퓨틱스 리미티드 펩타이드 활성화 제제
US20220409510A1 (en) * 2018-11-30 2022-12-29 Interk Peptide Therapeutics Limited Polypeptides And Methods For Improving Skin Conditions
CN110893236A (zh) * 2019-10-09 2020-03-20 中山大学 溶酶体靶向的抗体药物偶联物及其应用
CN112646018B (zh) * 2021-01-25 2023-04-28 井冈山大学 一种抑制肿瘤细胞增殖和转移的生物活性肽及其应用
US20240358790A1 (en) * 2021-08-20 2024-10-31 Interk Peptide Therapeutics Limited Compositions and methods for treating autoimmunity, including autoimmunity associated with cancer and cancer therapy

Citations (8)

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WO2001093836A2 (en) * 2000-06-09 2001-12-13 Teni Boulikas Encapsulation of polynucleotides and drugs into targeted liposomes
US20030040089A1 (en) * 2001-01-02 2003-02-27 Pierre Legrain Protein-protein interactions in adipocyte cells
WO2003044172A2 (en) * 2001-11-16 2003-05-30 Genentech, Inc. Composition comprising and method of using angiopoietin-like protein 3 angptl3
US6696546B1 (en) * 2000-11-06 2004-02-24 The Trustees Of Columbia University In The City Of New York Peptide that kills growing but not stationary cells
WO2005037308A1 (en) * 2003-10-17 2005-04-28 Inter-K Pty Limited Methods and agents for the treatment of cancer
WO2005105837A2 (en) * 2004-04-14 2005-11-10 Brigham And Women's Hospital, Inc. Use of the ribosomal protein rpl41 to treat infections and inhibit cancer
WO2009106073A2 (en) * 2008-02-28 2009-09-03 Dako Denmark A/S Mhc multimers in borrelia diagnostics and disease
WO2010039778A2 (en) * 2008-09-30 2010-04-08 Zirus, Inc. Mammalian genes involved in infection

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US20030162956A1 (en) 1997-04-07 2003-08-28 Human Genome Sciences, Inc. Leukocyte regulatory factors 1 and 2
ATE385503T1 (de) * 1999-06-28 2008-02-15 Inter K Pty Ltd Verfahren zur modulierung von integrin- vermittelter zellaktivitaet und hierfuer geeignete reagenzien
AUPR230500A0 (en) 2000-12-22 2001-01-25 University Of Newcastle Research Associates Limited, The A method of modulating map kinase mediated cellular activity and agents useful in same
US20030194798A1 (en) 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
CN102172406B (zh) 2001-10-15 2013-03-13 恩吉尼克分子传递私人有限公司 用作体外和体内dna转染与基因治疗载体的完整微细胞
EP1636385A4 (en) 2003-06-24 2010-06-02 Mirus Bio Corp INHIBITION OF GENE FUNCTION BY IN VIVO DISTRIBUTION OF GENE EXPRESSION INHIBITORS BASED ON POLYNUCLEOTIDES IN MAMMALIAN CELLS
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US20060194319A1 (en) 2004-09-02 2006-08-31 Webb Carol F Promoter substitution for immunoglobulin therapy
ES2407859T3 (es) 2004-09-13 2013-06-14 Genzyme Corporation Construcciones multiméricas.
WO2006029981A1 (en) 2004-09-13 2006-03-23 Vib Vzw Abin-mediated protection against lung inflammatory disease
US7429481B2 (en) 2004-09-14 2008-09-30 University Of Pittsburgh Targeting viruses using a modified sindbis glycoprotein
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WO2001093836A2 (en) * 2000-06-09 2001-12-13 Teni Boulikas Encapsulation of polynucleotides and drugs into targeted liposomes
US6696546B1 (en) * 2000-11-06 2004-02-24 The Trustees Of Columbia University In The City Of New York Peptide that kills growing but not stationary cells
US20030040089A1 (en) * 2001-01-02 2003-02-27 Pierre Legrain Protein-protein interactions in adipocyte cells
WO2003044172A2 (en) * 2001-11-16 2003-05-30 Genentech, Inc. Composition comprising and method of using angiopoietin-like protein 3 angptl3
WO2005037308A1 (en) * 2003-10-17 2005-04-28 Inter-K Pty Limited Methods and agents for the treatment of cancer
WO2005105837A2 (en) * 2004-04-14 2005-11-10 Brigham And Women's Hospital, Inc. Use of the ribosomal protein rpl41 to treat infections and inhibit cancer
WO2009106073A2 (en) * 2008-02-28 2009-09-03 Dako Denmark A/S Mhc multimers in borrelia diagnostics and disease
WO2010039778A2 (en) * 2008-09-30 2010-04-08 Zirus, Inc. Mammalian genes involved in infection

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Also Published As

Publication number Publication date
WO2013110120A1 (en) 2013-08-01
CN104271590B (zh) 2018-06-05
EP2807180A4 (en) 2016-01-06
US9403877B2 (en) 2016-08-02
CA2862485C (en) 2021-05-11
US20150110744A1 (en) 2015-04-23
EP2807180B1 (en) 2018-03-28
JP2015510393A (ja) 2015-04-09
CA2862485A1 (en) 2013-08-01
CN104271590A (zh) 2015-01-07
JP6249447B2 (ja) 2017-12-20
EP2807180A1 (en) 2014-12-03

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE NAME OF THE INVENTOR TO READ AGREZ, MICHAEL VALENTINE

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ PEPTIDE AGENTS FOR CANCER THERAPY

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