JP6205133B2 - 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー - Google Patents

抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー Download PDF

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JP6205133B2
JP6205133B2 JP2012519763A JP2012519763A JP6205133B2 JP 6205133 B2 JP6205133 B2 JP 6205133B2 JP 2012519763 A JP2012519763 A JP 2012519763A JP 2012519763 A JP2012519763 A JP 2012519763A JP 6205133 B2 JP6205133 B2 JP 6205133B2
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compound
alkenyl
alkynyl
heteroalkyl
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JP2012532887A5 (OSRAM
JP2012532887A (ja
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ウルフ，クリフォード，ジェイ．
ビーン，ブルース，ピー．
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Boston Childrens Hospital
Harvard University
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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JP2012519763A 2009-07-10 2010-07-09 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー Expired - Fee Related JP6205133B2 (ja)

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US22451209P 2009-07-10 2009-07-10
US61/224,512 2009-07-10
PCT/US2010/041537 WO2011006073A1 (en) 2009-07-10 2010-07-09 Permanently charged sodium and calcium channel blockers as anti-inflammatory agents

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JP2017086446A Division JP6530005B2 (ja) 2009-07-10 2017-04-25 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー

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JP2012532887A JP2012532887A (ja) 2012-12-20
JP2012532887A5 JP2012532887A5 (OSRAM) 2013-08-29
JP6205133B2 true JP6205133B2 (ja) 2017-09-27

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JP2012519763A Expired - Fee Related JP6205133B2 (ja) 2009-07-10 2010-07-09 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
JP2017086446A Expired - Fee Related JP6530005B2 (ja) 2009-07-10 2017-04-25 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
JP2019091784A Active JP6845280B2 (ja) 2009-07-10 2019-05-15 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
JP2021028224A Pending JP2021098713A (ja) 2009-07-10 2021-02-25 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー

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JP2019091784A Active JP6845280B2 (ja) 2009-07-10 2019-05-15 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
JP2021028224A Pending JP2021098713A (ja) 2009-07-10 2021-02-25 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー

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US (5) US20120172429A1 (OSRAM)
EP (3) EP3485881B1 (OSRAM)
JP (4) JP6205133B2 (OSRAM)
CN (1) CN102725401A (OSRAM)
AU (4) AU2010271269B2 (OSRAM)
CA (2) CA2767646C (OSRAM)
WO (1) WO2011006073A1 (OSRAM)

Cited By (3)

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JP2017178948A (ja) * 2009-07-10 2017-10-05 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
US10179116B2 (en) 2006-11-20 2019-01-15 President And Fellows Of Harvard College Methods, compositions, and kits for treating pain and pruritis
US11021443B2 (en) 2015-08-03 2021-06-01 President And Fellows Of Harvard College Charged ion channel blockers and methods for use

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CN107096014B (zh) 2010-09-29 2022-07-15 普马特里克斯营业公司 吸入用单价金属阳离子干粉剂
EP2654898A1 (en) * 2010-12-22 2013-10-30 Galderma Research & Development Modulators of trpa1 for the treatment of rosacea
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BR112013020874A2 (pt) 2011-02-18 2019-05-21 Endo Pharmaceuticals Inc. composto, regime, método para a preparação do referido composto, e, uso de um composto
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TWI603957B (zh) 2012-08-15 2017-11-01 阿沙納生物科學有限責任公司 胺基氫茚化合物用於治療膀胱過動症及間質性膀胱炎之用途
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JP6393680B2 (ja) 2013-05-23 2018-09-19 学校法人近畿大学 Ｔ型カルシウムチャネル阻害剤
WO2014187943A1 (en) * 2013-05-24 2014-11-27 Nestec S.A. Treatment or prevention of depression using menthol and/or icilin
TR201906539T4 (tr) * 2013-05-24 2019-05-21 Nestec Sa Mentol, Linalool ve/veya Icilin Kullanarak Beyin Travması ve İnmelerden Kaynaklanan Non-İnflamatuar Nöron Hasarının Tedavisi veya Önlenmesi.
US9700549B2 (en) 2013-10-03 2017-07-11 David Wise Compositions and methods for treating pelvic pain and other conditions
BR112017020307B1 (pt) 2015-03-26 2023-11-07 Jacqueline M. Iversen Usos de uma combinação de naproxeno e fexofenadina
CN106214670B (zh) * 2016-07-25 2020-12-29 上海璃道医药科技有限公司 酰胺类药物的用途
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JP7678757B2 (ja) 2019-03-11 2025-05-16 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
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JP7708777B2 (ja) * 2020-03-11 2025-07-15 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
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