MX2010009951A - Metodos, composiciones y kits para tratar dolor y prurito. - Google Patents

Metodos, composiciones y kits para tratar dolor y prurito.

Info

Publication number
MX2010009951A
MX2010009951A MX2010009951A MX2010009951A MX2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A
Authority
MX
Mexico
Prior art keywords
kits
compositions
methods
pruritis
treating pain
Prior art date
Application number
MX2010009951A
Other languages
English (en)
Inventor
Bruce P Bean
Clifford J Woolf
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of MX2010009951A publication Critical patent/MX2010009951A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La invención presenta métodos, composiciones, y kits para inhibición selectiva de neuronas detectoras de dolor y comezón (nociceptores y pruriceptores) por moléculas de fármaco de pese moléculas pequeño, mientras que minimiza los efectos sobre neuronas no detectoras de dolor u otros tipos de células.
MX2010009951A 2008-03-11 2009-03-11 Metodos, composiciones y kits para tratar dolor y prurito. MX2010009951A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6901808P 2008-03-11 2008-03-11
PCT/US2009/001541 WO2009114139A2 (en) 2008-03-11 2009-03-11 Methods, compositions, and kits for treating pain and pruritis

Publications (1)

Publication Number Publication Date
MX2010009951A true MX2010009951A (es) 2011-09-01

Family

ID=41065720

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010009951A MX2010009951A (es) 2008-03-11 2009-03-11 Metodos, composiciones y kits para tratar dolor y prurito.

Country Status (11)

Country Link
US (1) US20110086818A1 (es)
EP (1) EP2271329A4 (es)
JP (1) JP2011513484A (es)
KR (1) KR20110044166A (es)
CN (1) CN102112121A (es)
AU (1) AU2009223739A1 (es)
BR (1) BRPI0909627A2 (es)
CA (1) CA2717042A1 (es)
IL (1) IL208027A0 (es)
MX (1) MX2010009951A (es)
WO (1) WO2009114139A2 (es)

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DK2101819T3 (da) 2006-11-20 2013-04-29 Harvard College Fremgangsmåder, sammensætninger og kits til behandling af smerte og pruritis
US8637577B2 (en) 2009-01-22 2014-01-28 Absorption Pharmaceuticals, LLC Desensitizing drug product
EP3485881B1 (en) * 2009-07-10 2024-03-13 President and Fellows of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
JP5832856B2 (ja) * 2010-12-15 2015-12-16 久光製薬株式会社 局所鎮痛作用増強剤及び局所鎮痛キット
BR112013020874A2 (pt) 2011-02-18 2019-05-21 Endo Pharmaceuticals Inc. composto, regime, método para a preparação do referido composto, e, uso de um composto
JP6495654B2 (ja) 2011-10-24 2019-04-03 アサナ バイオサイエンシズ，リミティド ライアビリティ カンパニー シクロヘキシルアミン類
US8779003B2 (en) 2011-12-29 2014-07-15 Mackay Memorial Hospital Method and composition for prolonging analgesic effect of local anesthetic
TWI603957B (zh) 2012-08-15 2017-11-01 阿沙納生物科學有限責任公司 胺基氫茚化合物用於治療膀胱過動症及間質性膀胱炎之用途
CN111557432B (zh) 2013-02-08 2023-08-04 通用磨坊公司 低钠食品
WO2015160843A1 (en) * 2014-04-14 2015-10-22 Flex Pharma, Inc. Ion channel activators and methods of use
CA2994545A1 (en) * 2015-08-03 2017-02-09 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
CN106214678B (zh) * 2016-07-26 2020-12-29 上海璃道医药科技有限公司 苯酮类药物的用途
EP3570861A4 (en) 2017-01-23 2020-11-18 Flex Pharma, Inc. COMPOSITIONS AND PROCEDURES EFFECTING SPORTING PERFORMANCE
KR101877002B1 (ko) * 2017-03-06 2018-07-12 서울대학교 산학협력단 피라졸 유도체를 유효성분으로 함유하는 소양증의 예방 또는 치료용 약학적 조성물 및 이를 검출하기 위한 스크리닝 방법
KR101867779B1 (ko) * 2017-12-08 2018-06-19 서울대학교산학협력단 피라졸 유도체를 유효성분으로 함유하는 소양증의 예방 또는 치료용 약학적 조성물 및 이를 검출하기 위한 스크리닝 방법
US11591375B2 (en) * 2018-01-22 2023-02-28 Oregon State University Immunogenic compositions comprising Mycobacterium bovis surface proteins and uses thereof
KR20210044803A (ko) * 2018-08-15 2021-04-23 파마실 아베 치환된 벤즈아미드 및 치료법에서 이의 용도
CN109498604A (zh) * 2018-12-24 2019-03-22 复旦大学 香叶醇新用途，预防和治疗非疾病引起的瘙痒症的配制品及方法
KR20210145164A (ko) 2019-03-11 2021-12-01 녹시온 테라퓨틱스 인코포레이티드 에스테르 치환된 이온 채널 차단제 및 사용 방법
CA3129117A1 (en) 2019-03-11 2020-09-17 Bridget Mccarthy Cole Charged ion channel blockers and methods for use
JP2022525856A (ja) 2019-03-11 2022-05-20 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
IL292505A (en) 2019-11-06 2022-06-01 Nocion Therapeutics Inc Charged ion channel blockers and methods of use
EP4054586A4 (en) 2019-11-06 2023-11-22 Nocion Therapeutics, Inc. CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE
WO2021173916A1 (en) * 2020-02-27 2021-09-02 President And Fellows Of Harvard College Nociceptor neurons control cancer immunosurveillance
CN115243683A (zh) * 2020-03-04 2022-10-25 纽克尔斯有限公司 Qx314防止与施用trpv1调节剂相关的交感神经兴奋的用途
AU2021236130A1 (en) * 2020-03-11 2022-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN113509457B (zh) * 2020-09-07 2023-03-21 四川昇嘉科技有限公司 山椒素在制备治疗湿疹的药物中的用途
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413961B1 (en) * 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
US20030166629A1 (en) * 1999-12-15 2003-09-04 Choi Lewis Siu Leung Cyclic quaternary ammonium compounds
WO2002089849A1 (en) * 2001-05-07 2002-11-14 Corium International Compositions and delivery systems for administration of a local anesthetic agent
WO2004091521A2 (en) * 2003-04-10 2004-10-28 Neurogesx, Inc. Methods and compositions for administration of trpv1 agonists
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
CN102764247B (zh) * 2004-01-30 2016-04-20 考里安国际公司 递送活性剂的快速溶解膜
AU2005249572A1 (en) * 2004-06-02 2005-12-15 Neurogesx, Inc. Formulations comprising a capsaicinoid a local anesthetic and/or an antipruritic agent for the treatment of pain
DK2101819T3 (da) * 2006-11-20 2013-04-29 Harvard College Fremgangsmåder, sammensætninger og kits til behandling af smerte og pruritis

Also Published As

Publication number Publication date
EP2271329A4 (en) 2013-01-09
AU2009223739A1 (en) 2009-09-17
BRPI0909627A2 (pt) 2018-04-10
KR20110044166A (ko) 2011-04-28
EP2271329A2 (en) 2011-01-12
WO2009114139A3 (en) 2009-12-23
WO2009114139A2 (en) 2009-09-17
IL208027A0 (en) 2010-12-30
US20110086818A1 (en) 2011-04-14
JP2011513484A (ja) 2011-04-28
CA2717042A1 (en) 2009-09-17
CN102112121A (zh) 2011-06-29

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