TR201906539T4 - Mentol, Linalool ve/veya Icilin Kullanarak Beyin Travması ve İnmelerden Kaynaklanan Non-İnflamatuar Nöron Hasarının Tedavisi veya Önlenmesi. - Google Patents
Mentol, Linalool ve/veya Icilin Kullanarak Beyin Travması ve İnmelerden Kaynaklanan Non-İnflamatuar Nöron Hasarının Tedavisi veya Önlenmesi. Download PDFInfo
- Publication number
- TR201906539T4 TR201906539T4 TR2019/06539T TR201906539T TR201906539T4 TR 201906539 T4 TR201906539 T4 TR 201906539T4 TR 2019/06539 T TR2019/06539 T TR 2019/06539T TR 201906539 T TR201906539 T TR 201906539T TR 201906539 T4 TR201906539 T4 TR 201906539T4
- Authority
- TR
- Turkey
- Prior art keywords
- strokes
- prevention
- damage caused
- linalool
- menthol
- Prior art date
Links
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 title abstract 4
- 208000030886 Traumatic Brain injury Diseases 0.000 title abstract 3
- 230000003961 neuronal insult Effects 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 title abstract 2
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 title abstract 2
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 title abstract 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 title abstract 2
- 229930007744 linalool Natural products 0.000 title abstract 2
- 229940041616 menthol Drugs 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 230000002757 inflammatory effect Effects 0.000 abstract 2
- RCEFMOGVOYEGJN-UHFFFAOYSA-N 3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-1,4-dihydropyrimidin-2-one Chemical compound OC1=CC=CC=C1N1C(=O)NC(C=2C=C(C=CC=2)[N+]([O-])=O)=CC1 RCEFMOGVOYEGJN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Beyin travmasından ve inmelerden kaynaklanan non-inflamatuar nöron hasarının önlenmesi için bileşimler sağlanmaktadır ve bileşimler Mentol, Linalool, Icilin ve bunların kombinasyonlarından meydana gelen gruptan seçilmiş bir bileşiğin terapötik olarak etkili miktarını içermektedir. Beyin travması ve inmelerden kaynaklanan non-inflamatuar nöron hasarının tedavisi veya önlenmesi için yöntemler de sağlanmaktadır ve yöntemler bu gibi bileşimlerin uygulanmasını içermektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361827232P | 2013-05-24 | 2013-05-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201906539T4 true TR201906539T4 (tr) | 2019-05-21 |
Family
ID=50819728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/06539T TR201906539T4 (tr) | 2013-05-24 | 2014-05-23 | Mentol, Linalool ve/veya Icilin Kullanarak Beyin Travması ve İnmelerden Kaynaklanan Non-İnflamatuar Nöron Hasarının Tedavisi veya Önlenmesi. |
Country Status (10)
Country | Link |
---|---|
US (2) | US20160166570A1 (tr) |
EP (1) | EP3003292B1 (tr) |
JP (2) | JP2016520588A (tr) |
CN (1) | CN105228601A (tr) |
AU (2) | AU2014270341A1 (tr) |
BR (1) | BR112015026484A2 (tr) |
CA (1) | CA2908365C (tr) |
ES (1) | ES2721922T3 (tr) |
TR (1) | TR201906539T4 (tr) |
WO (1) | WO2014187945A1 (tr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2721922T3 (es) * | 2013-05-24 | 2019-08-06 | Nestle Sa | Tratamiento o prevención del daño neuronal no inflamatorio por traumatismo cerebral e ictus utilizando mentol, linalool y/o icilina |
CN116018134A (zh) * | 2020-03-24 | 2023-04-25 | 洪明奇 | 薄荷醇用于制备治疗神经退化症及中风的外用组合物的用途 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2483635A1 (en) * | 2002-04-25 | 2003-11-06 | Alon Shalev | Methods and apparatus for modifying properties of the bbb and cerebral circulation by using the neuroexcitatory and/or neuroinhibitory effects of odorants on nerves in the head |
JP4742204B2 (ja) * | 2005-01-21 | 2011-08-10 | 財団法人ヒューマンサイエンス振興財団 | 脂肪細胞分化制御剤 |
JP2007291069A (ja) * | 2006-03-31 | 2007-11-08 | Daiichi Sankyo Healthcare Co Ltd | 抗酸化剤および/または消炎鎮痛剤組成物 |
GB0615136D0 (en) * | 2006-07-29 | 2006-09-06 | Univ Edinburgh | Induction of analgesia in neuropathic pain |
KR20090085237A (ko) * | 2008-02-04 | 2009-08-07 | 김병문 | 천연 진주가루를 함유한 뇌질환 예방 및 치료용 한약조성물 |
JP6205133B2 (ja) * | 2009-07-10 | 2017-09-27 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー |
KR20120103317A (ko) * | 2011-03-10 | 2012-09-19 | 한국생명공학연구원 | 아실 코에이:콜레스테롤 아실트랜스퍼라제 저해활성을 갖는 고수씨 추출물 또는 이로부터 분리된 리나로올을 포함하는 조성물 |
SI2793883T1 (en) * | 2011-12-19 | 2018-08-31 | Dompe Farmaceutici S.P.A. | Antagonists TRPM8 |
CN102512634A (zh) * | 2011-12-26 | 2012-06-27 | 神威药业(张家口)有限公司 | 复方麝香软胶囊及其制备方法 |
CN104284668B (zh) * | 2012-05-07 | 2018-04-20 | 以色列国家农业和农村发展部农业科研组织(Aro)(沃尔卡尼中心) | 用于治疗神经变性疾病的天竺葵精油及其成分 |
ES2721922T3 (es) * | 2013-05-24 | 2019-08-06 | Nestle Sa | Tratamiento o prevención del daño neuronal no inflamatorio por traumatismo cerebral e ictus utilizando mentol, linalool y/o icilina |
-
2014
- 2014-05-23 ES ES14726347T patent/ES2721922T3/es active Active
- 2014-05-23 JP JP2016514431A patent/JP2016520588A/ja not_active Withdrawn
- 2014-05-23 CN CN201480029057.2A patent/CN105228601A/zh active Pending
- 2014-05-23 US US14/892,287 patent/US20160166570A1/en not_active Abandoned
- 2014-05-23 TR TR2019/06539T patent/TR201906539T4/tr unknown
- 2014-05-23 EP EP14726347.9A patent/EP3003292B1/en active Active
- 2014-05-23 WO PCT/EP2014/060637 patent/WO2014187945A1/en active Application Filing
- 2014-05-23 BR BR112015026484A patent/BR112015026484A2/pt not_active Application Discontinuation
- 2014-05-23 CA CA2908365A patent/CA2908365C/en active Active
- 2014-05-23 AU AU2014270341A patent/AU2014270341A1/en not_active Abandoned
-
2017
- 2017-03-17 US US15/462,387 patent/US10799502B2/en active Active
-
2019
- 2019-08-26 AU AU2019222781A patent/AU2019222781B2/en active Active
- 2019-09-26 JP JP2019175366A patent/JP2020011985A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US20170189403A1 (en) | 2017-07-06 |
JP2020011985A (ja) | 2020-01-23 |
AU2014270341A1 (en) | 2015-10-08 |
AU2019222781B2 (en) | 2021-05-13 |
JP2016520588A (ja) | 2016-07-14 |
EP3003292B1 (en) | 2019-03-20 |
US20160166570A1 (en) | 2016-06-16 |
CA2908365C (en) | 2023-02-28 |
CA2908365A1 (en) | 2014-11-27 |
BR112015026484A2 (pt) | 2017-07-25 |
ES2721922T3 (es) | 2019-08-06 |
US10799502B2 (en) | 2020-10-13 |
AU2019222781A1 (en) | 2019-09-12 |
CN105228601A (zh) | 2016-01-06 |
WO2014187945A1 (en) | 2014-11-27 |
EP3003292A1 (en) | 2016-04-13 |
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