JP6193275B2 - B細胞媒介炎症性疾患を治療するための方法 - Google Patents

B細胞媒介炎症性疾患を治療するための方法 Download PDF

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JP6193275B2
JP6193275B2 JP2014560085A JP2014560085A JP6193275B2 JP 6193275 B2 JP6193275 B2 JP 6193275B2 JP 2014560085 A JP2014560085 A JP 2014560085A JP 2014560085 A JP2014560085 A JP 2014560085A JP 6193275 B2 JP6193275 B2 JP 6193275B2
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seq
antibody
amino acid
cxcl13
acid residues
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JP2015509960A5 (OSRAM
JP2015509960A (ja
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スミス,アーネスト・エス
ザウダラー,モーリス
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ヴァクシネックス, インコーポレイテッド
ヴァクシネックス, インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2014560085A 2012-03-02 2013-03-01 B細胞媒介炎症性疾患を治療するための方法 Active JP6193275B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261606049P 2012-03-02 2012-03-02
US61/606,049 2012-03-02
PCT/US2013/028602 WO2013130959A1 (en) 2012-03-02 2013-03-01 Methods for the treatment of b cell-mediated inflammatory diseases

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JP2015509960A JP2015509960A (ja) 2015-04-02
JP2015509960A5 JP2015509960A5 (OSRAM) 2016-04-21
JP6193275B2 true JP6193275B2 (ja) 2017-09-06

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Country Link
US (1) US9890213B2 (OSRAM)
EP (1) EP2820045B1 (OSRAM)
JP (1) JP6193275B2 (OSRAM)
KR (1) KR102090969B1 (OSRAM)
CN (1) CN104520323B (OSRAM)
AU (1) AU2013225812B2 (OSRAM)
CA (1) CA2865928C (OSRAM)
IN (1) IN2014DN08199A (OSRAM)
NZ (1) NZ629828A (OSRAM)
WO (1) WO2013130959A1 (OSRAM)

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Also Published As

Publication number Publication date
IN2014DN08199A (OSRAM) 2015-05-01
NZ629828A (en) 2017-05-26
AU2013225812A1 (en) 2014-09-25
WO2013130959A1 (en) 2013-09-06
EP2820045B1 (en) 2018-08-22
AU2013225812B2 (en) 2017-11-30
US9890213B2 (en) 2018-02-13
CN104520323B (zh) 2018-05-04
CA2865928A1 (en) 2013-09-06
CA2865928C (en) 2021-02-16
KR20140138830A (ko) 2014-12-04
EP2820045A1 (en) 2015-01-07
US20150125467A1 (en) 2015-05-07
CN104520323A (zh) 2015-04-15
JP2015509960A (ja) 2015-04-02
KR102090969B1 (ko) 2020-03-19

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