KR102090969B1 - B 세포-매개 염증 질환의 치료 방법 - Google Patents

B 세포-매개 염증 질환의 치료 방법 Download PDF

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KR102090969B1
KR102090969B1 KR1020147027747A KR20147027747A KR102090969B1 KR 102090969 B1 KR102090969 B1 KR 102090969B1 KR 1020147027747 A KR1020147027747 A KR 1020147027747A KR 20147027747 A KR20147027747 A KR 20147027747A KR 102090969 B1 KR102090969 B1 KR 102090969B1
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seq
antibody
amino acid
leu
cxcl13
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KR20140138830A (ko
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어네스트 에스. 스미스
모리스 저더러
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백시넥스 인코포레이티드
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020147027747A 2012-03-02 2013-03-01 B 세포-매개 염증 질환의 치료 방법 Active KR102090969B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261606049P 2012-03-02 2012-03-02
US61/606,049 2012-03-02
PCT/US2013/028602 WO2013130959A1 (en) 2012-03-02 2013-03-01 Methods for the treatment of b cell-mediated inflammatory diseases

Publications (2)

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KR20140138830A KR20140138830A (ko) 2014-12-04
KR102090969B1 true KR102090969B1 (ko) 2020-03-19

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KR1020147027747A Active KR102090969B1 (ko) 2012-03-02 2013-03-01 B 세포-매개 염증 질환의 치료 방법

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Country Link
US (1) US9890213B2 (OSRAM)
EP (1) EP2820045B1 (OSRAM)
JP (1) JP6193275B2 (OSRAM)
KR (1) KR102090969B1 (OSRAM)
CN (1) CN104520323B (OSRAM)
AU (1) AU2013225812B2 (OSRAM)
CA (1) CA2865928C (OSRAM)
IN (1) IN2014DN08199A (OSRAM)
NZ (1) NZ629828A (OSRAM)
WO (1) WO2013130959A1 (OSRAM)

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AU2010245668B2 (en) 2009-05-08 2016-07-14 Vaccinex, Inc. Anti-CD100 antibodies and methods for using the same
US9963504B2 (en) 2010-09-02 2018-05-08 Vaccinex, Inc. Anti-CXCL13 antibodies and methods of using the same
BR112014008885B1 (pt) 2011-10-11 2021-02-17 Vaccinex, Inc uso de um anticorpo isolado ou fragmento de ligação ao antígeno do mesmo que se liga especificamente à semaforina-4d para diminuir permeabilidade da barreira hematoencefálica (bbb) em um indivíduo com permeabilidade da bbb aumentada e um transtorno neuroinflamatório
US9708601B2 (en) 2012-04-26 2017-07-18 Vaccinex, Inc. Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus
KR102176962B1 (ko) 2013-01-31 2020-11-10 백시넥스 인코포레이티드 면역글로불린 a 수준을 증가시키기 위한 방법
EA036591B1 (ru) 2013-06-25 2020-11-26 Вэксинекс, Инк. Способ ингибирования, замедления или уменьшения роста раковой опухоли у субъекта
SG11201808554TA (en) 2016-04-22 2018-11-29 Vaccinex Inc Integral membrane protein display on poxvirus extracellular enveloped virions
RU2747557C2 (ru) 2016-08-02 2021-05-06 Вэксинекс, Инк. Улучшенные способы получения библиотек полинуклеотидов в вирусах осповакцины/эукариотических клетках
KR101953706B1 (ko) * 2016-09-19 2019-03-05 아이-맵 항-gm-csf 항체 및 이것의 사용
KR20210016557A (ko) * 2018-05-31 2021-02-16 글리콤 에이/에스 자가면역 질환 치료를 위한 hmo 혼합물
SG11202010499UA (en) * 2018-09-18 2020-11-27 I Mab Biopharma Us Ltd Anti-cxcl13 antibodies for treating autoimmune diseases and cancer

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Also Published As

Publication number Publication date
JP6193275B2 (ja) 2017-09-06
CN104520323A (zh) 2015-04-15
US20150125467A1 (en) 2015-05-07
WO2013130959A1 (en) 2013-09-06
JP2015509960A (ja) 2015-04-02
NZ629828A (en) 2017-05-26
KR20140138830A (ko) 2014-12-04
AU2013225812A1 (en) 2014-09-25
EP2820045B1 (en) 2018-08-22
CN104520323B (zh) 2018-05-04
US9890213B2 (en) 2018-02-13
EP2820045A1 (en) 2015-01-07
CA2865928A1 (en) 2013-09-06
AU2013225812B2 (en) 2017-11-30
CA2865928C (en) 2021-02-16
IN2014DN08199A (OSRAM) 2015-05-01

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