JP6178805B2 - ナノ細孔センサーとともに使用するための二重層を作製するための方法 - Google Patents

ナノ細孔センサーとともに使用するための二重層を作製するための方法 Download PDF

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JP6178805B2
JP6178805B2 JP2014557852A JP2014557852A JP6178805B2 JP 6178805 B2 JP6178805 B2 JP 6178805B2 JP 2014557852 A JP2014557852 A JP 2014557852A JP 2014557852 A JP2014557852 A JP 2014557852A JP 6178805 B2 JP6178805 B2 JP 6178805B2
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molecule
nanopore
electrode
lipid
probe
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JP2015508896A5 (enExample
JP2015508896A (ja
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ランダル デイビス，
ランダル デイビス，
ロジャー チェン，
ロジャー チェン，
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ジニア テクノロジーズ， インコーポレイテッド
ジニア テクノロジーズ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules
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    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00734—Lipids
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
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  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2014557852A 2012-02-16 2013-02-15 ナノ細孔センサーとともに使用するための二重層を作製するための方法 Active JP6178805B2 (ja)

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US201261599871P 2012-02-16 2012-02-16
US61/599,871 2012-02-16
US201261600398P 2012-02-17 2012-02-17
US61/600,398 2012-02-17
PCT/US2013/026514 WO2013123450A1 (en) 2012-02-16 2013-02-15 Methods for creating bilayers for use with nanopore sensors

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JP2017049533A Active JP6431108B2 (ja) 2012-02-16 2017-03-15 標的分子を検出する方法
JP2018034689A Active JP6617167B2 (ja) 2012-02-16 2018-02-28 ナノ細孔センサーとともに使用するための二重層を作製するための方法
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CA (1) CA2864125C (enExample)
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