JP6139886B2 - ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ - Google Patents

ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ Download PDF

Info

Publication number
JP6139886B2
JP6139886B2 JP2012539940A JP2012539940A JP6139886B2 JP 6139886 B2 JP6139886 B2 JP 6139886B2 JP 2012539940 A JP2012539940 A JP 2012539940A JP 2012539940 A JP2012539940 A JP 2012539940A JP 6139886 B2 JP6139886 B2 JP 6139886B2
Authority
JP
Japan
Prior art keywords
hemoglobin
binds
antibody
seq
hbs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2012539940A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013511717A5 (https=
JP2013511717A (ja
Inventor
ウォーカー ロジャー
ウォーカー ロジャー
ジャルダン ベネディクト
ジャルダン ベネディクト
Original Assignee
バイオ−ラッド ラボラトリーズ，インコーポレイティド
バイオ−ラッド ラボラトリーズ，インコーポレイティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイオ−ラッド ラボラトリーズ，インコーポレイティド, バイオ−ラッド ラボラトリーズ，インコーポレイティド filed Critical バイオ−ラッド ラボラトリーズ，インコーポレイティド
Publication of JP2013511717A publication Critical patent/JP2013511717A/ja
Publication of JP2013511717A5 publication Critical patent/JP2013511717A5/ja
Application granted granted Critical
Publication of JP6139886B2 publication Critical patent/JP6139886B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2012539940A 2009-11-18 2010-11-09 ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ Active JP6139886B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26248809P 2009-11-18 2009-11-18
US61/262,488 2009-11-18
US12/941,738 US8603828B2 (en) 2009-11-18 2010-11-08 Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms
US12/941,738 2010-11-08
PCT/US2010/055952 WO2011062803A2 (en) 2009-11-18 2010-11-09 Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015209371A Division JP2016028254A (ja) 2009-11-18 2015-10-23 ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ

Publications (3)

Publication Number Publication Date
JP2013511717A JP2013511717A (ja) 2013-04-04
JP2013511717A5 JP2013511717A5 (https=) 2013-06-20
JP6139886B2 true JP6139886B2 (ja) 2017-05-31

Family

ID=44011571

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012539940A Active JP6139886B2 (ja) 2009-11-18 2010-11-09 ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ
JP2015209371A Pending JP2016028254A (ja) 2009-11-18 2015-10-23 ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015209371A Pending JP2016028254A (ja) 2009-11-18 2015-10-23 ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ

Country Status (8)

Country Link
US (5) US8603828B2 (https=)
EP (3) EP3043182B1 (https=)
JP (2) JP6139886B2 (https=)
AU (3) AU2010322233B2 (https=)
CA (1) CA2781255C (https=)
ES (1) ES2665958T3 (https=)
PT (1) PT3043182T (https=)
WO (1) WO2011062803A2 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8603828B2 (en) * 2009-11-18 2013-12-10 Bio-Rad Laboratories, Inc. Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms
US11435358B2 (en) 2011-06-23 2022-09-06 Board Of Regents, The University Of Texas System Single molecule peptide sequencing
WO2015099123A1 (ja) * 2013-12-26 2015-07-02 京セラ株式会社 センサ
EP3404413B1 (en) 2014-03-20 2020-01-01 Bio-Rad Laboratories, Inc. Glycated protein assay
WO2015157669A1 (en) 2014-04-11 2015-10-15 Siemens Healthcare Diagnostics Inc. Spectroscopic methods for the detection of glycated hemoglobin
US20160116489A1 (en) * 2014-10-23 2016-04-28 Biomedomics, Inc. Lateral flow immunoassay method of simultaneously detecting hemoglobin s, hemoglobin c, and hemoglobin a in newborns, infants, children, and adults
WO2016109378A1 (en) 2014-12-29 2016-07-07 North Carolina State University Multiplexed diagnostic to recognize concentrations of related proteins and peptides
JP6692834B2 (ja) 2015-02-09 2020-05-13 スリングショット バイオサイエンシーズ， インコーポレイテッド 調整可能な光学特性を有するヒドロゲル粒子およびその使用の方法
JP6492856B2 (ja) * 2015-03-25 2019-04-03 東ソー株式会社 安定型糖化ヘモグロビンＡ１ｃの定量方法
US20190023806A1 (en) * 2015-10-21 2019-01-24 Qoolabs, Inc. Camelid hemoglobin antibodies and methods of use
WO2017096373A1 (en) * 2015-12-04 2017-06-08 Polymer Technology Systems, Inc. Systems and methods for interference correction from hemoglobin variants
WO2017141514A1 (ja) 2016-02-17 2017-08-24 株式会社デンソー 車両用空調ユニット
US12345718B2 (en) * 2016-11-04 2025-07-01 Université Paris Est Créteil Val De Marne Method for determining the haemoglobin content of an erythroid cell
US10317413B2 (en) 2016-11-14 2019-06-11 The Board Of Regents Of The University Of Texas System Method and kit for detection of anti-zika virus antibodies
US11535681B2 (en) * 2017-12-15 2022-12-27 Bluebird Bio, Inc. Sickled beta globin antibodies
CA3110800A1 (en) 2018-07-12 2020-01-16 Board Of Regents, The University Of Texas System Molecular neighborhood detection by oligonucleotides
SG11202103027UA (en) * 2018-09-28 2021-04-29 Sekisui Medical Co Ltd Glycated hemoglobin (%) assay method
CA3117476A1 (en) 2018-10-05 2020-04-09 Board Of Regents, The University Of Texas System Solid-phase n-terminal peptide capture and release
US20220163543A1 (en) * 2019-03-04 2022-05-26 Siemens Healthcare Diagnostics Inc. Dried reagent polysaccharide surface area stabilization
US20200284807A1 (en) * 2019-03-05 2020-09-10 Victor Manneh Saturation binding ratiometric assay
KR20220129585A (ko) 2020-01-24 2022-09-23 슬링샷 바이오사이언시즈 인코포레이티드 세포-유사 보정 입자를 위한 조성물 및 방법
JP7807395B2 (ja) 2020-05-04 2026-01-27 スリングショット バイオサイエンシーズ， インコーポレイテッド 多重化アッセイのためのパッシブ光学バーコード付与のための組成物および方法
AU2022376541A1 (en) 2021-10-29 2024-04-18 Slingshot Biosciences, Inc. Hydrogel particles as feeder cells and as synthetic antigen presenting cells
WO2023195348A1 (ja) * 2022-04-04 2023-10-12 デンカ株式会社 抗ヒトヘモグロビンα鎖モノクローナル抗体又はその抗原結合性断片、ヒトヘモグロビン及び／又は糖化ヒトヘモグロビンを検出する方法、ヒトヘモグロビン及び／又は糖化ヒトヘモグロビンの検出キット、並びに、ペプチド
WO2023196898A1 (en) * 2022-04-07 2023-10-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Beta globin mimetic peptides and their use
CN119907921A (zh) 2022-05-05 2025-04-29 弹弓生物科学公司 用于血液学的作为红细胞模拟物的工程化颗粒和含有工程化颗粒的组合物
CA3257621A1 (en) 2022-06-02 2023-12-07 Slingshot Biosciences, Inc. APOPTOTIC CELL MIMETIC
CN120712108A (zh) 2022-10-26 2025-09-26 弹弓生物科学公司 具有可调整光学性质的大小可调整合成颗粒和用于使用其进行免疫细胞激活的方法
WO2025049609A1 (en) 2023-08-29 2025-03-06 Slingshot Biosciences, Inc. Cd34 stem cell mimics

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2632478A1 (de) 1975-07-23 1977-02-24 Coulter Electronics Verfahren zur erfassung und trennung von antigenen und antikoerperchen im blut und in anderen proben
US4752583A (en) * 1984-11-29 1988-06-21 The United States Of America As Represented By The United States Department Of Energy Monoclonal antibodies to human hemoglobin S and cell lines for the production thereof
US5428754A (en) 1988-03-23 1995-06-27 3Dlabs Ltd Computer system with clock shared between processors executing separate instruction streams
US5922854A (en) * 1991-06-14 1999-07-13 Kumar; Ramesh Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids
DE69332138T2 (de) 1992-03-04 2003-03-27 Abbott Laboratories, Abbott Park Bestimmung von glykosyliertem hämoglobin durch dämpfung der fluoreszenz
US6043043A (en) * 1993-04-02 2000-03-28 Bayer Corporation Method for the determination of hemoglobin adducts
US6933106B2 (en) 1995-03-13 2005-08-23 Mark Hechinger Platelet immunoglobulin bead suspension and flow cytometry
US6951716B2 (en) 1995-03-13 2005-10-04 Mark Hechinger Anti-platelet immunoglobulin bead positive control
EP1015028A2 (en) * 1997-09-19 2000-07-05 Serex, Inc. Methods to improve immunogenicity of antigens and specificity of antibodies
DE69812329T2 (de) 1997-11-18 2004-02-12 Bio-Rad Laboratories, Inc., Hercules Multiplex-zufluss-immunotest mit magnetischen teilchen als festphase
US7271009B1 (en) * 1997-11-18 2007-09-18 Bio-Rad Laboratories, Inc. Multi-analyte diagnostic test for thyroid disorders
DE69830854T2 (de) 1997-12-04 2006-04-20 Amersham Biosciences Uk Ltd., Amersham Mehrfaches testverfahren
US20020115116A1 (en) 2001-02-22 2002-08-22 Yong Song Multiplex protein interaction determinations using glutathione-GST binding
WO2002088185A2 (en) * 2001-04-26 2002-11-07 Dakocytomation Denmark A/S Pan-specific monoclonal antibody
US20040101874A1 (en) * 2002-04-12 2004-05-27 Mitokor Inc. Targets for therapeutic intervention identified in the mitochondrial proteome
US7326573B2 (en) 2003-01-10 2008-02-05 Beckman Coulter, Inc. Assay procedures and apparatus
US20040229284A1 (en) 2003-02-19 2004-11-18 The Regents Of The University Of California Multiplex analysis of proteins
US20040214243A1 (en) 2003-04-25 2004-10-28 Beckman Coulter, Inc. Differential determination of hemoglobins
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20080108144A1 (en) * 2004-05-27 2008-05-08 Alam Muhammad A Method for the Rapid Analysis of Polypeptides
JP2006052480A (ja) 2004-08-10 2006-02-23 Nisshinbo Ind Inc セルロース系繊維含有布帛の加工方法及びセルロース系繊維含有布帛
GB0502068D0 (en) * 2005-02-01 2005-03-09 King S College London Screening method
JPWO2006129751A1 (ja) 2005-06-03 2009-01-08 ニプロ株式会社 メチオニンアミノペプチダーゼ遺伝子を含む高コピー高発現ベクター
US7521244B2 (en) * 2006-10-26 2009-04-21 Bionostics, Inc. Standard reference solutions
EP2210113B1 (en) * 2007-11-20 2015-05-27 Siemens Healthcare Diagnostics Inc. Methods for the detection of glycated hemoglobin
US8260556B2 (en) 2008-08-21 2012-09-04 Bio-Rad Laboratories, Inc. Calibration surface method for determination on of analyte ratios
CA2765457A1 (en) * 2009-07-07 2011-01-13 Uvic Industry Partnerships Inc. Methods for early detection of blood disorders
US8603828B2 (en) * 2009-11-18 2013-12-10 Bio-Rad Laboratories, Inc. Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms

Also Published As

Publication number Publication date
ES2665958T3 (es) 2018-04-30
US20170176462A1 (en) 2017-06-22
EP3043182B1 (en) 2018-01-17
JP2016028254A (ja) 2016-02-25
US9605060B2 (en) 2017-03-28
AU2010322233A1 (en) 2012-06-21
WO2011062803A3 (en) 2011-07-28
AU2017200733A1 (en) 2017-02-23
PT3043182T (pt) 2018-04-23
US20140073532A1 (en) 2014-03-13
CA2781255A1 (en) 2011-05-26
CA2781255C (en) 2017-08-01
US8603828B2 (en) 2013-12-10
US20190018023A1 (en) 2019-01-17
EP3043182A1 (en) 2016-07-13
EP2502080B1 (en) 2016-04-13
EP3301452A1 (en) 2018-04-04
EP2502080A2 (en) 2012-09-26
EP3301452B1 (en) 2020-01-08
JP2013511717A (ja) 2013-04-04
US9213034B2 (en) 2015-12-15
WO2011062803A2 (en) 2011-05-26
US10088488B2 (en) 2018-10-02
AU2019200070B2 (en) 2020-07-16
AU2010322233B2 (en) 2016-11-03
AU2019200070A1 (en) 2019-01-31
US20110117670A1 (en) 2011-05-19
EP2502080A4 (en) 2013-03-27
US20160068594A1 (en) 2016-03-10
US11262366B2 (en) 2022-03-01
AU2017200733B2 (en) 2018-10-11

Similar Documents

Publication Publication Date Title
JP6139886B2 (ja) ヘモグロビン、ヘモグロビンバリアント、及び糖化フォームの多重免疫アッセイ
EP0573972B1 (en) Method for measuring glycated hemoglobin
JP5199067B2 (ja) 免疫凝集反応試薬キット及び抗原の測定方法
EP3859332B1 (en) Glycated hemoglobin (%) assay method
CN112326973B (zh) 一种用于检测新型冠状病毒抗体的试剂盒及其应用
JP2677753B2 (ja) 凝集イムノアッセイ法
JP3833358B2 (ja) 被検体の亜集団の測定のための均一検出方法
US20180238876A1 (en) Method For Assessing Cell Surface Receptors of Blood Cells
WO2018138139A1 (en) Method for assessing cell surface receptors of blood cells
CN110133270A (zh) 一种增强免疫抑制比浊抗体筛选试剂及其制作和使用方法
JPH06167495A (ja) 凝集イムノアッセイ法
CN117285624B (zh) 抗犬NT-proBNP双特异性抗体及试剂盒

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130422

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20131108

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140709

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140715

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20141014

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20141021

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150115

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20150623

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151023

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20151030

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20151228

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20160915

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161220

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170216

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20170428

R150 Certificate of patent or registration of utility model

Ref document number: 6139886

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250