JP6093712B2 - インターロイキン2のスーパーアゴニストおよびアンタゴニスト - Google Patents

インターロイキン2のスーパーアゴニストおよびアンタゴニスト Download PDF

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JP6093712B2
JP6093712B2 JP2013546430A JP2013546430A JP6093712B2 JP 6093712 B2 JP6093712 B2 JP 6093712B2 JP 2013546430 A JP2013546430 A JP 2013546430A JP 2013546430 A JP2013546430 A JP 2013546430A JP 6093712 B2 JP6093712 B2 JP 6093712B2
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cells
mutein
cell
amino acid
binding protein
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JP2014502967A (ja
JP2014502967A5 (cg-RX-API-DMAC7.html
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ガルシア,ケナン,クリストファー
レビン,アロン
リング,アーロン
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Leland Stanford Junior University
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2013546430A 2010-12-22 2011-12-22 インターロイキン2のスーパーアゴニストおよびアンタゴニスト Active JP6093712B2 (ja)

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US201061426307P 2010-12-22 2010-12-22
US61/426,307 2010-12-22
PCT/US2011/066911 WO2012088446A1 (en) 2010-12-22 2011-12-22 Superagonists and antagonists of interleukin-2

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JP2014502967A5 JP2014502967A5 (cg-RX-API-DMAC7.html) 2017-01-05
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US (4) US9428567B2 (cg-RX-API-DMAC7.html)
EP (2) EP3211001B1 (cg-RX-API-DMAC7.html)
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CA (1) CA2860170C (cg-RX-API-DMAC7.html)
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