JP6066350B2 - エアロゾルボーラスとしてのイロプロストの投与 - Google Patents

エアロゾルボーラスとしてのイロプロストの投与 Download PDF

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Publication number
JP6066350B2
JP6066350B2 JP2014506856A JP2014506856A JP6066350B2 JP 6066350 B2 JP6066350 B2 JP 6066350B2 JP 2014506856 A JP2014506856 A JP 2014506856A JP 2014506856 A JP2014506856 A JP 2014506856A JP 6066350 B2 JP6066350 B2 JP 6066350B2
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Japan
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composition
inhalation
aerosol
inhaler
iloprost
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JP2014506856A
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English (en)
Japanese (ja)
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JP2014513091A (ja
JP2014513091A5 (enExample
Inventor
ゲスラー トビアス
ゲスラー トビアス
シェメール トーマス
シェメール トーマス
ゼーガー ベルナー
ゼーガー ベルナー
フォスビンケル ロベルト
フォスビンケル ロベルト
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ベクチュラ・ゲーエムベーハー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5578—Eicosanoids, e.g. leukotrienes or prostaglandins having a pentalene ring system, e.g. carbacyclin, iloprost
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0085—Inhalators using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0024—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with an on-off output signal, e.g. from a switch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014506856A 2011-04-26 2012-04-26 エアロゾルボーラスとしてのイロプロストの投与 Active JP6066350B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11163659.3 2011-04-26
EP11163659 2011-04-26
PCT/EP2012/057615 WO2012146642A1 (en) 2011-04-26 2012-04-26 Administration of iloprost as aerosol bolus

Publications (3)

Publication Number Publication Date
JP2014513091A JP2014513091A (ja) 2014-05-29
JP2014513091A5 JP2014513091A5 (enExample) 2016-06-09
JP6066350B2 true JP6066350B2 (ja) 2017-01-25

Family

ID=44534909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014506856A Active JP6066350B2 (ja) 2011-04-26 2012-04-26 エアロゾルボーラスとしてのイロプロストの投与

Country Status (19)

Country Link
US (2) US20140155486A1 (enExample)
EP (2) EP2965748A1 (enExample)
JP (1) JP6066350B2 (enExample)
KR (1) KR101718372B1 (enExample)
CN (2) CN103619323B (enExample)
AU (1) AU2012247562B2 (enExample)
CA (1) CA2834063C (enExample)
CL (1) CL2013003057A1 (enExample)
CO (1) CO6821944A2 (enExample)
ES (1) ES2625282T3 (enExample)
IL (1) IL228182B (enExample)
NZ (1) NZ616048A (enExample)
PH (1) PH12013502152B1 (enExample)
PL (1) PL2701683T3 (enExample)
PT (1) PT2701683T (enExample)
RU (1) RU2605849C2 (enExample)
TW (1) TWI602568B (enExample)
WO (1) WO2012146642A1 (enExample)
ZA (1) ZA201307908B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104853744B (zh) * 2012-10-31 2018-01-19 维克多瑞有限责任公司 气溶胶化伊洛前列素的给药
US20160303040A1 (en) * 2013-11-19 2016-10-20 Rigshospitalet Injectable pharmaceutical compositions comprising prostacyclin
EP3082428A4 (en) 2013-12-09 2017-08-02 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
WO2017201349A1 (en) 2016-05-18 2017-11-23 Modernatx, Inc. Polynucleotides encoding citrin for the treatment of citrullinemia type 2
KR20220050839A (ko) 2019-05-16 2022-04-25 에어로베이트 테라퓨틱스, 인크. 이마티닙 제제, 그의 제조법 및 용도
US20250000873A1 (en) * 2021-09-10 2025-01-02 Justus-Liebig-Universitaet Giessen Inhaled iloprost for rescue treatment and treatment as needed in pulmonary hypertension
CN113952320B (zh) * 2021-09-18 2022-03-18 健康元药业集团股份有限公司 一种包含妥布霉素吸入溶液的药物组件及其用途
CN113712526B (zh) * 2021-09-30 2022-12-30 四川大学 一种脉搏波提取方法、装置、电子设备及存储介质
CN114652704A (zh) * 2022-04-29 2022-06-24 兆科药业（广州）有限公司 一种曲前列尼尔软雾吸入剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6972869B2 (en) 2000-12-18 2005-12-06 Xerox Corporation Mapping color to colorant amounts when colorants have similar hue
CN101090714A (zh) 2004-07-26 2007-12-19 康泽里克斯公司 通过吸入伊洛前列素和微粒制剂治疗肺动脉高血压症
EP1712220A1 (en) * 2005-04-15 2006-10-18 PARI GmbH Spezialisten für effektive Inhalation Pharmaceutical aerosol composition
WO2007134292A2 (en) * 2006-05-15 2007-11-22 United Therapeutics Corporation Treprostinil administration using a metered dose inhaler
WO2010008424A2 (en) 2008-04-04 2010-01-21 Novartis Ag Aerosolization device
US8668901B2 (en) * 2009-02-04 2014-03-11 Activaero Gmbh Research & Development Use of a glucocorticoid composition for the treatment of severe and uncontrolled asthma

Also Published As

Publication number Publication date
RU2013151018A (ru) 2015-06-27
TWI602568B (zh) 2017-10-21
US20140155486A1 (en) 2014-06-05
PT2701683T (pt) 2017-05-03
WO2012146642A1 (en) 2012-11-01
US10821116B2 (en) 2020-11-03
CA2834063C (en) 2016-01-05
CN106420676B (zh) 2020-04-28
US20170014424A1 (en) 2017-01-19
JP2014513091A (ja) 2014-05-29
PH12013502152A1 (en) 2014-01-13
ZA201307908B (en) 2014-07-30
EP2701683B1 (en) 2017-03-08
CN103619323A (zh) 2014-03-05
CN103619323B (zh) 2016-08-17
PH12013502152B1 (en) 2018-12-14
PL2701683T3 (pl) 2017-08-31
CO6821944A2 (es) 2013-12-31
TW201249442A (en) 2012-12-16
CL2013003057A1 (es) 2014-08-01
EP2701683A1 (en) 2014-03-05
HK1190627A1 (zh) 2014-07-11
IL228182B (en) 2018-07-31
NZ616048A (en) 2015-07-31
ES2625282T3 (es) 2017-07-19
AU2012247562B2 (en) 2015-12-17
CA2834063A1 (en) 2012-11-01
CN106420676A (zh) 2017-02-22
EP2965748A1 (en) 2016-01-13
AU2012247562A1 (en) 2013-09-26
KR20140012114A (ko) 2014-01-29
RU2605849C2 (ru) 2016-12-27
KR101718372B1 (ko) 2017-03-21

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