JP6050328B2 - Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用 - Google Patents

Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用 Download PDF

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JP6050328B2
JP6050328B2 JP2014510798A JP2014510798A JP6050328B2 JP 6050328 B2 JP6050328 B2 JP 6050328B2 JP 2014510798 A JP2014510798 A JP 2014510798A JP 2014510798 A JP2014510798 A JP 2014510798A JP 6050328 B2 JP6050328 B2 JP 6050328B2
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pharmaceutical composition
composition according
administered
lymphoma
maytansinoid immunoconjugate
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JP2014515036A (ja
JP2014515036A5 (OSRAM
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モラリユー，ロデイカ
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Sanofi SA
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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JP2014510798A 2011-05-17 2012-05-16 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用 Expired - Fee Related JP6050328B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11290232.5 2011-05-17
EP11290232A EP2524929A1 (en) 2011-05-17 2011-05-17 Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms
PCT/EP2012/059141 WO2012156455A1 (en) 2011-05-17 2012-05-16 Use of anti-cd19 maytansinoid immunoconjugate antibody for the treatment of b-cell malignancies symptoms

Related Child Applications (1)

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JP2016226407A Division JP6181273B2 (ja) 2011-05-17 2016-11-22 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用

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JP2014515036A JP2014515036A (ja) 2014-06-26
JP2014515036A5 JP2014515036A5 (OSRAM) 2014-08-07
JP6050328B2 true JP6050328B2 (ja) 2016-12-21

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JP2014510798A Expired - Fee Related JP6050328B2 (ja) 2011-05-17 2012-05-16 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用
JP2016226407A Expired - Fee Related JP6181273B2 (ja) 2011-05-17 2016-11-22 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用
JP2017138852A Pending JP2018021020A (ja) 2011-05-17 2017-07-18 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用
JP2019087962A Pending JP2019142961A (ja) 2011-05-17 2019-05-08 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用

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JP2016226407A Expired - Fee Related JP6181273B2 (ja) 2011-05-17 2016-11-22 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用
JP2017138852A Pending JP2018021020A (ja) 2011-05-17 2017-07-18 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用
JP2019087962A Pending JP2019142961A (ja) 2011-05-17 2019-05-08 Ｂ細胞悪性腫瘍の症状の治療のための抗ｃｄ１９メイタンシンノイドイムノコンジュゲート抗体の使用

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US (2) US9555126B2 (OSRAM)
EP (2) EP2524929A1 (OSRAM)
JP (4) JP6050328B2 (OSRAM)
KR (1) KR20140043388A (OSRAM)
CN (2) CN107007840A (OSRAM)
AR (1) AR086412A1 (OSRAM)
AU (3) AU2012258254B2 (OSRAM)
BR (1) BR112013029330A8 (OSRAM)
CA (1) CA2835738A1 (OSRAM)
CL (1) CL2013003272A1 (OSRAM)
CO (1) CO6821893A2 (OSRAM)
CR (1) CR20130593A (OSRAM)
DO (1) DOP2013000260A (OSRAM)
EA (1) EA028574B1 (OSRAM)
EC (1) ECSP13013084A (OSRAM)
GT (1) GT201300276A (OSRAM)
IL (3) IL229380B (OSRAM)
MA (1) MA35180B1 (OSRAM)
MX (1) MX347019B (OSRAM)
MY (1) MY163736A (OSRAM)
NI (1) NI201300119A (OSRAM)
PE (1) PE20141018A1 (OSRAM)
PH (2) PH12013502305A1 (OSRAM)
SG (2) SG10201609729VA (OSRAM)
TN (1) TN2013000468A1 (OSRAM)
TW (3) TWI601537B (OSRAM)
UA (1) UA114401C2 (OSRAM)
UY (1) UY34077A (OSRAM)
WO (1) WO2012156455A1 (OSRAM)
ZA (1) ZA201309400B (OSRAM)

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PT3916392T (pt) 2016-05-30 2024-06-04 Incyte Corp Métodos para prever o benefício terapêutico da terapia anti-cd19 nos pacientes
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CN110845617B (zh) * 2019-12-05 2021-07-09 常州费洛斯药业科技有限公司 针对cd19的全人源抗体或抗体片段、嵌合抗原受体及应用
JP2023530499A (ja) 2020-06-22 2023-07-18 モルフォシス・アーゲー 抗ＣＤ１９抗体及びＳＩＲＰα－ＣＤ４７自然免疫チェックポイントを遮断するポリペプチドを含む抗腫瘍組み合わせ療法
TW202229349A (zh) 2020-10-06 2022-08-01 美商山可爾股份有限公司 用於治療包括全身性紅斑性狼瘡(sle)的自體免疫疾病之生物標記、方法及組合物
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EP2710034A1 (en) 2014-03-26
IL257475A (en) 2018-06-28
US9555126B2 (en) 2017-01-31
TW201834687A (zh) 2018-10-01
TW201726167A (zh) 2017-08-01
CN103547596A (zh) 2014-01-29
WO2012156455A1 (en) 2012-11-22
TW201249460A (en) 2012-12-16
EP2524929A1 (en) 2012-11-21
EA201391714A1 (ru) 2014-03-31
MA35180B1 (fr) 2014-06-02
CL2013003272A1 (es) 2014-08-01
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IL229380A0 (en) 2014-01-30
NZ618012A (en) 2016-03-31
CN107007840A (zh) 2017-08-04
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JP2014515036A (ja) 2014-06-26
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US20140072587A1 (en) 2014-03-13
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