JP6043715B2 - 小型ｈｐｌｃ装置 - Google Patents

小型ｈｐｌｃ装置 Download PDF

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Publication number
JP6043715B2
JP6043715B2 JP2013515975A JP2013515975A JP6043715B2 JP 6043715 B2 JP6043715 B2 JP 6043715B2 JP 2013515975 A JP2013515975 A JP 2013515975A JP 2013515975 A JP2013515975 A JP 2013515975A JP 6043715 B2 JP6043715 B2 JP 6043715B2
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Japan
Prior art keywords
liquid
container
gas
liquid chromatography
column
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Expired - Fee Related
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JP2013515975A
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English (en)
Japanese (ja)
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JP2013529780A (ja
JP2013529780A5 (enExample
Inventor
ロバート ケーシー，ダンカン
ロバート ケーシー，ダンカン
ジョン カプリンスカイ，ジョセフ
ジョン カプリンスカイ，ジョセフ
サーレヒー−レイハニ，アリ
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Ip2ipo Innovations Ltd
Original Assignee
Imperial Innovations Ltd
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Publication of JP2013529780A publication Critical patent/JP2013529780A/ja
Publication of JP2013529780A5 publication Critical patent/JP2013529780A5/ja
Application granted granted Critical
Publication of JP6043715B2 publication Critical patent/JP6043715B2/ja
Expired - Fee Related legal-status Critical Current
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/22—Injection in high pressure liquid systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/36—Control of physical parameters of the fluid carrier in high pressure liquid systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/324—Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/326—Control of physical parameters of the fluid carrier of pressure or speed pumps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Fluid Mechanics (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2013515975A 2010-06-25 2011-06-27 小型ｈｐｌｃ装置 Expired - Fee Related JP6043715B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1010737.3A GB201010737D0 (en) 2010-06-25 2010-06-25 Minature HPLC device
GB1010737.3 2010-06-25
PCT/GB2011/051217 WO2011161481A1 (en) 2010-06-25 2011-06-27 Miniature hplc device

Publications (3)

Publication Number Publication Date
JP2013529780A JP2013529780A (ja) 2013-07-22
JP2013529780A5 JP2013529780A5 (enExample) 2014-08-14
JP6043715B2 true JP6043715B2 (ja) 2016-12-14

Family

ID=42583011

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013515975A Expired - Fee Related JP6043715B2 (ja) 2010-06-25 2011-06-27 小型ｈｐｌｃ装置

Country Status (10)

Country Link
US (1) US9354209B2 (enExample)
EP (1) EP2585820A1 (enExample)
JP (1) JP6043715B2 (enExample)
CN (2) CN103180726B (enExample)
AU (1) AU2011268682B2 (enExample)
BR (1) BR112012032726A2 (enExample)
CA (1) CA2803962A1 (enExample)
GB (1) GB201010737D0 (enExample)
WO (1) WO2011161481A1 (enExample)
ZA (1) ZA201300607B (enExample)

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GB201213537D0 (en) * 2012-07-30 2012-09-12 Imp Innovations Ltd Self-limiting injection assembly for sample introduction in HPLC
WO2014055331A1 (en) * 2012-10-03 2014-04-10 Waters Technologies Corporation A chromatography column
CN103439309A (zh) * 2013-08-19 2013-12-11 南通大学 高灵敏度的co气体光谱传感器的制备方法
TWI579553B (zh) 2013-11-24 2017-04-21 中央研究院 以紫外光－可見光檢測之高效能液相層析設備及方法
WO2015110860A1 (en) * 2014-01-24 2015-07-30 Dh Technologies Development Pte. Ltd. Systems and methods for delivering liquid to an ion source
GB2534936B (en) * 2015-02-06 2021-09-08 Agilent Technologies Inc Liquid chromatography analysis unit
JP6704920B2 (ja) * 2015-10-14 2020-06-03 アルプスアルパイン株式会社 流路構造体および測定対象液体の測定装置
US9513220B1 (en) 2015-12-29 2016-12-06 International Business Machines Corporation On-chip molecule fluorescence detection
FR3055703B1 (fr) * 2016-09-05 2020-12-18 Elichens Procede d’analyse d’un gaz
JP6696578B2 (ja) * 2016-09-26 2020-05-20 株式会社島津製作所 切替バルブ、バイナリポンプ及びそのバイナリポンプを備えた液体クロマトグラフ
CN116183705A (zh) * 2017-03-30 2023-05-30 九零八图案公司 生物样品的微射流分析
EP3756002B1 (en) * 2018-02-23 2023-11-29 Silcotek Corp. Liquid chromatography technique
CN108593813B (zh) * 2018-07-17 2020-04-10 厦门大学 手持式一体化液相色谱仪
WO2022153571A1 (ja) * 2021-01-15 2022-07-21 エースバイオアナリシス株式会社 走査ユニット、システムおよび方法、ならびにマイクロカラム

Family Cites Families (26)

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FR2389891B1 (enExample) * 1977-05-02 1981-07-03 Prolabo Sa
EP0583003A1 (en) 1992-08-13 1994-02-16 Perseptive Biosystems, Inc. Fluid metering, mixing and composition control system
US5408326A (en) * 1993-04-28 1995-04-18 Shell Oil Company Dual-wavelength absorption detector adapted for continuous-flow detection
US6277257B1 (en) 1997-06-25 2001-08-21 Sandia Corporation Electrokinetic high pressure hydraulic system
JPH11287791A (ja) * 1998-04-01 1999-10-19 Naohiro Soga キャピラリーカラム
JP2003502655A (ja) * 1999-06-22 2003-01-21 アジレント・テクノロジーズ・インコーポレーテッド 微小流体デバイスの操作用装置
US20030223913A1 (en) * 2002-06-03 2003-12-04 Nanostream, Inc. Microfluidic separation devices and methods
US20040124085A1 (en) * 2002-06-26 2004-07-01 California Institute Of Technology Microfluidic devices and methods with electrochemically actuated sample processing
US7530257B2 (en) * 2002-09-27 2009-05-12 Honeywell International Inc. Phased micro analyzer VIII
US7700745B2 (en) * 2003-02-28 2010-04-20 Japan Science And Technology Agency Method for separating carbohydrate in glycoside-linkage-having compound, carbohydrate separating system, carbohydrate separating reagent kit, standard sample for carbohydrate separation, and evaluation system
JP4307221B2 (ja) * 2003-11-11 2009-08-05 株式会社日立ハイテクノロジーズ 進捗管理方法及び装置
CN1749750A (zh) * 2004-09-13 2006-03-22 聂智明 高效液相色谱仪
CN1755351A (zh) * 2004-09-30 2006-04-05 中国科学院大连化学物理研究所 发光二极管诱导荧光微型检测器
CN100406886C (zh) * 2005-06-22 2008-07-30 夏之宁 一种微型化的液相色谱分离方法
JP2009508729A (ja) 2005-09-21 2009-03-05 ウオーターズ・インベストメンツ・リミテツド 高圧チュービング
JP2009516162A (ja) * 2005-11-11 2009-04-16 モレキュラー・ビジョン・リミテッド マイクロ流体装置
JP2007163252A (ja) * 2005-12-13 2007-06-28 Sekisui Chem Co Ltd 液体クロマトグラフ用測定カートリッジ及び液体クロマトグラフ装置
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CN1963497A (zh) * 2006-11-08 2007-05-16 浙江大学 微分析芯片上的微液相色谱分离方法及其装置
CN101206205B (zh) * 2006-12-22 2011-08-10 中国科学院大连化学物理研究所 微流量液相色谱在线大体积进样的方法和专用装置
JP4946647B2 (ja) * 2007-06-14 2012-06-06 株式会社島津製作所 試料前処理装置及び液体クロマトグラフ装置
KR100966590B1 (ko) 2007-12-11 2010-06-29 한국전자통신연구원 생체신호 측정 장치들의 상호 협업 방법 및 시스템
JP5181650B2 (ja) * 2007-12-13 2013-04-10 株式会社島津製作所 分析システム

Also Published As

Publication number Publication date
JP2013529780A (ja) 2013-07-22
GB201010737D0 (en) 2010-08-11
EP2585820A1 (en) 2013-05-01
US20130219999A1 (en) 2013-08-29
CN103180726A (zh) 2013-06-26
CA2803962A1 (en) 2011-12-29
ZA201300607B (en) 2014-05-26
AU2011268682A1 (en) 2013-01-10
AU2011268682B2 (en) 2015-01-29
CN105004821A (zh) 2015-10-28
CN103180726B (zh) 2015-07-01
US9354209B2 (en) 2016-05-31
BR112012032726A2 (pt) 2018-02-27
WO2011161481A1 (en) 2011-12-29

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