JP6040987B2 - 改変型アルカリホスファターゼ - Google Patents

改変型アルカリホスファターゼ Download PDF

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Publication number
JP6040987B2
JP6040987B2 JP2014523743A JP2014523743A JP6040987B2 JP 6040987 B2 JP6040987 B2 JP 6040987B2 JP 2014523743 A JP2014523743 A JP 2014523743A JP 2014523743 A JP2014523743 A JP 2014523743A JP 6040987 B2 JP6040987 B2 JP 6040987B2
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Japan
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alkaline phosphatase
amino acid
lysine
derived
seq
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JP2014523743A
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Japanese (ja)
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JPWO2014007229A1 (ja
Inventor
洋志 相場
洋志 相場
岸本　高英
高英 岸本
柳谷　周作
周作 柳谷
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Toyobo Co Ltd
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Toyobo Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2014523743A 2012-07-06 2013-07-02 改変型アルカリホスファターゼ Active JP6040987B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012152219 2012-07-06
JP2012152219 2012-07-06
PCT/JP2013/068085 WO2014007229A1 (ja) 2012-07-06 2013-07-02 改変型アルカリホスファターゼ

Related Child Applications (1)

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JP2016118930A Division JP2016168051A (ja) 2012-07-06 2016-06-15 改変型アルカリホスファターゼ

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JPWO2014007229A1 JPWO2014007229A1 (ja) 2016-06-02
JP6040987B2 true JP6040987B2 (ja) 2016-12-07

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JP2014523743A Active JP6040987B2 (ja) 2012-07-06 2013-07-02 改変型アルカリホスファターゼ
JP2016118930A Pending JP2016168051A (ja) 2012-07-06 2016-06-15 改変型アルカリホスファターゼ

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JP2016118930A Pending JP2016168051A (ja) 2012-07-06 2016-06-15 改変型アルカリホスファターゼ

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JP (2) JP6040987B2 (enExample)
WO (1) WO2014007229A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6732368B2 (ja) * 2016-01-12 2020-07-29 東ソー株式会社 アルカリホスファターゼ及びその製造方法
EP3737750B1 (en) * 2018-01-09 2024-06-05 Theriva Biologics, Inc. Alkaline phosphatase agents for treatment of neurodevelopmental disorders
WO2019183209A1 (en) * 2018-03-20 2019-09-26 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of radiation disorders
WO2020067121A1 (ja) * 2018-09-25 2020-04-02 東レ株式会社 アルカリホスファターゼ組成物並びに脱リン酸化核酸及び標識化核酸の製造方法
JPWO2022196538A1 (enExample) * 2021-03-17 2022-09-22

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ208612A (en) * 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
US4904584A (en) * 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
JP2008005734A (ja) * 2006-06-28 2008-01-17 Kikkoman Corp アルカリホスファターゼ
CN103380213B (zh) * 2011-02-23 2016-01-20 东洋纺株式会社 碱性磷酸酶

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WO2014007229A1 (ja) 2014-01-09
JP2016168051A (ja) 2016-09-23
JPWO2014007229A1 (ja) 2016-06-02

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