JP6039566B2 - 治療用、診断用および抗体組成物に関連したトリプトファニルｔＲＮＡ合成酵素のタンパク質フラグメントの革新的発見 - Google Patents

治療用、診断用および抗体組成物に関連したトリプトファニルｔＲＮＡ合成酵素のタンパク質フラグメントの革新的発見 Download PDF

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JP6039566B2
JP6039566B2 JP2013532947A JP2013532947A JP6039566B2 JP 6039566 B2 JP6039566 B2 JP 6039566B2 JP 2013532947 A JP2013532947 A JP 2013532947A JP 2013532947 A JP2013532947 A JP 2013532947A JP 6039566 B2 JP6039566 B2 JP 6039566B2
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polypeptide
protein
seq
cell
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JP2013544779A5 (enExample
JP2013544779A (ja
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レスリー アン グリーン，
レスリー アン グリーン，
カイル ピー． チャン，
カイル ピー． チャン，
フェイ ホン，
フェイ ホン，
アレイン ピー． バサロット，
アレイン ピー． バサロット，
ウィン−セー ロー，
ウィン−セー ロー，
ジェフリー ディー． ワトキンス，
ジェフリー ディー． ワトキンス，
シェリル エル． クイン，
シェリル エル． クイン，
ジョン ディー． メンドレイン，
ジョン ディー． メンドレイン，
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エータイアー ファーマ， インコーポレイテッド
エータイアー ファーマ， インコーポレイテッド
パング バイオファーマ リミテッド
パング バイオファーマ リミテッド
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/53—Ligases (6)
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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    • C12Y—ENZYMES
    • C12Y601/00—Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01—Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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JP2013532947A 2010-10-06 2011-10-06 治療用、診断用および抗体組成物に関連したトリプトファニルｔＲＮＡ合成酵素のタンパク質フラグメントの革新的発見 Active JP6039566B2 (ja)

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US39055510P 2010-10-06 2010-10-06
US39055410P 2010-10-06 2010-10-06
US39055310P 2010-10-06 2010-10-06
US61/390,554 2010-10-06
US61/390,553 2010-10-06
US61/390,555 2010-10-06
PCT/US2011/055130 WO2012048125A2 (en) 2010-10-06 2011-10-06 Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases

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JP2015186665A Division JP2016000052A (ja) 2010-10-06 2015-09-24 治療用、診断用および抗体組成物に関連したトリプトファニルｔＲＮＡ合成酵素のタンパク質フラグメントの革新的発見

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JP2013544779A5 JP2013544779A5 (enExample) 2014-05-22
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JP2015186665A Withdrawn JP2016000052A (ja) 2010-10-06 2015-09-24 治療用、診断用および抗体組成物に関連したトリプトファニルｔＲＮＡ合成酵素のタンパク質フラグメントの革新的発見

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