JP6019118B2 - 吸入に適した酸化型アビジンの医薬品組成物 - Google Patents
吸入に適した酸化型アビジンの医薬品組成物 Download PDFInfo
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- JP6019118B2 JP6019118B2 JP2014523289A JP2014523289A JP6019118B2 JP 6019118 B2 JP6019118 B2 JP 6019118B2 JP 2014523289 A JP2014523289 A JP 2014523289A JP 2014523289 A JP2014523289 A JP 2014523289A JP 6019118 B2 JP6019118 B2 JP 6019118B2
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- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
- A61K47/665—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells the pre-targeting system, clearing therapy or rescue therapy involving biotin-(strept) avidin systems
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A—HUMAN NECESSITIES
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- A61P11/06—Antiasthmatics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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| Application Number | Priority Date | Filing Date | Title |
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| EP11006338 | 2011-08-02 | ||
| EP11006338.5 | 2011-08-02 | ||
| PCT/EP2012/064576 WO2013017494A1 (en) | 2011-08-02 | 2012-07-25 | Pharmaceutical composition of oxidised avidin suitable for inhalation |
Publications (3)
| Publication Number | Publication Date |
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| JP2014521675A JP2014521675A (ja) | 2014-08-28 |
| JP2014521675A5 JP2014521675A5 (enExample) | 2015-08-27 |
| JP6019118B2 true JP6019118B2 (ja) | 2016-11-02 |
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| EP2941243A4 (en) | 2013-01-04 | 2016-09-14 | Massachusetts Inst Technology | SURFACE BINDING IN THE ADMINISTRATION OF A MEDICAMENT ON NANOPARTICLE BASE IN A TISSUE |
| EP3458097A4 (en) * | 2016-05-19 | 2020-01-08 | University of Miami | TARGETED DELIVERY OF THERAPEUTIC AGENTS AND IMAGING REAGENTS TO CANCER PANCREAS CELLS |
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| US5384128A (en) * | 1993-03-02 | 1995-01-24 | University Of Alabama Research Foundation | Method of and compounds for treatment for cystic fibrosis |
| JPH09501418A (ja) | 1993-07-19 | 1997-02-10 | アムジエン・インコーポレーテツド | エアゾル化タンパク質の安定化 |
| DE69830305T2 (de) * | 1997-02-20 | 2006-02-02 | Dime, David S., Toronto | Ortsspezifische arzneimittel verabreichung |
| HK1042234A1 (zh) * | 1999-04-13 | 2002-08-09 | Nektar Therapeutics | 向肺部施加乾粉配方以治疗不育症 |
| US7001994B2 (en) * | 2001-01-18 | 2006-02-21 | Genzyme Corporation | Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins |
| ITRM20010079A1 (it) | 2001-02-16 | 2002-08-16 | Sigma Tau Ind Farmaceuti | Amminoderivati della biotina e loro coniugati con chelanti macrociclici. |
| ITRM20030196A1 (it) * | 2003-04-24 | 2004-10-25 | Sigma Tau Ind Farmaceuti | Uso di reagenti per la preparazione di un medicamento |
| EP2311793A1 (en) * | 2004-12-17 | 2011-04-20 | Cipla Ltd. | Crystalline levosalbutamol sulphate (Form II) |
| GB0602778D0 (en) * | 2006-02-10 | 2006-03-22 | Glaxo Group Ltd | Novel compound |
| KR101544628B1 (ko) * | 2007-08-02 | 2015-08-17 | 시구마-토우인더스트리에파아마슈우티히리유니트에스.피이.에이. | 처리 조직에서의 체류 시간이 긴 산화 아비딘 |
| EP2106806A1 (en) * | 2008-03-31 | 2009-10-07 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Nanoparticles for targeted delivery of active agents to the lung |
| TW201031436A (en) * | 2009-02-16 | 2010-09-01 | Univ Nat Taiwan | Pharmaceutical composition for inhalation delivery and fabrication method thereof |
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Also Published As
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| EP2739314A1 (en) | 2014-06-11 |
| ES2729549T3 (es) | 2019-11-04 |
| PL2739314T3 (pl) | 2019-09-30 |
| EA026453B1 (ru) | 2017-04-28 |
| MX355177B (es) | 2018-04-09 |
| CN103717239A (zh) | 2014-04-09 |
| BR112014002593A2 (pt) | 2017-03-01 |
| ZA201401921B (en) | 2015-05-27 |
| PH12014500193A1 (en) | 2014-03-24 |
| US20140134106A1 (en) | 2014-05-15 |
| CA2842276C (en) | 2020-11-24 |
| AU2012292229A1 (en) | 2014-02-13 |
| US9872831B2 (en) | 2018-01-23 |
| CA2842276A1 (en) | 2013-02-07 |
| KR20140047668A (ko) | 2014-04-22 |
| NZ620202A (en) | 2016-05-27 |
| EP2739314B1 (en) | 2019-05-22 |
| CN103717239B (zh) | 2017-08-01 |
| DK2739314T3 (da) | 2019-06-24 |
| KR101966630B1 (ko) | 2019-04-09 |
| IL230597A0 (en) | 2014-03-31 |
| MX2014001176A (es) | 2014-07-14 |
| EA201490401A1 (ru) | 2014-05-30 |
| WO2013017494A1 (en) | 2013-02-07 |
| BR112014002593B1 (pt) | 2022-11-29 |
| UA114482C2 (uk) | 2017-06-26 |
| PT2739314T (pt) | 2019-06-21 |
| AU2012292229B2 (en) | 2017-08-03 |
| JP2014521675A (ja) | 2014-08-28 |
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