JP6013376B2 - 包埋生体試料の前処置のための2相非混和系 - Google Patents
包埋生体試料の前処置のための2相非混和系 Download PDFInfo
- Publication number
- JP6013376B2 JP6013376B2 JP2013555948A JP2013555948A JP6013376B2 JP 6013376 B2 JP6013376 B2 JP 6013376B2 JP 2013555948 A JP2013555948 A JP 2013555948A JP 2013555948 A JP2013555948 A JP 2013555948A JP 6013376 B2 JP6013376 B2 JP 6013376B2
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- JP
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- Prior art keywords
- reagent
- carrier composition
- pretreatment
- sample
- biological sample
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
- G01N2001/366—Moulds; Demoulding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161447364P | 2011-02-28 | 2011-02-28 | |
| US61/447,364 | 2011-02-28 | ||
| PCT/IB2012/000405 WO2012117294A2 (en) | 2011-02-28 | 2012-02-28 | Two phase immiscible system for the pretreatment of embedded biological samples |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014523514A JP2014523514A (ja) | 2014-09-11 |
| JP2014523514A5 JP2014523514A5 (enExample) | 2015-03-19 |
| JP6013376B2 true JP6013376B2 (ja) | 2016-10-25 |
Family
ID=46758338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013555948A Active JP6013376B2 (ja) | 2011-02-28 | 2012-02-28 | 包埋生体試料の前処置のための2相非混和系 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10295442B2 (enExample) |
| EP (1) | EP2686662B1 (enExample) |
| JP (1) | JP6013376B2 (enExample) |
| CN (2) | CN107255584B (enExample) |
| AU (3) | AU2012222963B2 (enExample) |
| CA (1) | CA2826056C (enExample) |
| WO (1) | WO2012117294A2 (enExample) |
Families Citing this family (21)
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| WO2009147537A2 (en) | 2008-05-27 | 2009-12-10 | Dako Denmark A/S | Compositions and methods for detection of chromosomal aberrations with novel hybridization buffers |
| EP2401395A1 (en) | 2009-02-26 | 2012-01-04 | Dako Denmark A/S | Compositions and methods for rna hybridization applications |
| EP3252173A1 (en) * | 2011-10-21 | 2017-12-06 | Dako Denmark A/S | Hybridization compositions and methods |
| US8701980B2 (en) | 2011-10-27 | 2014-04-22 | Veltek Associates, Inc. | Air sample tracking system and method |
| DE102013204646B4 (de) * | 2013-03-15 | 2018-04-05 | Leica Biosystems Nussloch Gmbh | Gerät zum Bearbeiten von histologischen Proben |
| US10839509B2 (en) | 2015-07-10 | 2020-11-17 | 3Scan Inc. | Spatial multiplexing of histological stains |
| US10281374B2 (en) * | 2015-11-04 | 2019-05-07 | Diagnostic Biosystems | Method of pretreatment of biological samples for an analyte-staining assay method |
| EP3410093A4 (en) * | 2016-01-29 | 2020-02-12 | Sysmex Corporation | SAMPLE COLORING DEVICE, SWEAT PREPARATION DEVICE AND SAMPLE COLORING METHOD |
| US10613005B2 (en) | 2016-10-31 | 2020-04-07 | Agilent Technologies, Inc. | Deparaffinization of tissue by electric field generation and ionization |
| US10379015B2 (en) | 2017-06-04 | 2019-08-13 | Diagnostic Biosystems | Method for labeling concentration density differentials of an analyte in a biological sample |
| CN107828862A (zh) * | 2017-12-15 | 2018-03-23 | 郑州大学第附属医院 | 淋巴瘤组织石蜡包埋切片荧光原位杂交检测的预处理方法 |
| WO2019195677A1 (en) * | 2018-04-05 | 2019-10-10 | Instapath, Inc. | Disposable biopsy staining kit and related methods and systems |
| US11525759B2 (en) | 2018-04-24 | 2022-12-13 | Agilent Technologies, Inc. | Deparaffinization of tissue utilizing electric field |
| CN109142012A (zh) * | 2018-08-17 | 2019-01-04 | 上海迈景纳米科技有限公司 | 一种ffpe样本快速脱蜡装置及其使用方法 |
| CN113785184B (zh) * | 2019-05-14 | 2025-02-28 | 文塔纳医疗系统公司 | 包括生物学样品处理腔室的系统 |
| CN110132673B (zh) * | 2019-05-22 | 2021-06-15 | 上海市农业科学院 | 一种制备金针菇子实体组织切片的方法 |
| CN112113822A (zh) * | 2019-06-21 | 2020-12-22 | 深圳迈瑞生物医疗电子股份有限公司 | 生物样本染色装置、推片染色机及生物样本染色方法 |
| CN111238912A (zh) * | 2020-03-12 | 2020-06-05 | 河南农业大学 | 一种叶片切片包埋的方法和叶片制片方法 |
| EP4193137A4 (en) * | 2020-08-10 | 2024-05-22 | Leica Biosystems Nussloch GmbH | Xylene-free tissue processor and method for processing tissue |
| CN113092219B (zh) * | 2021-03-24 | 2025-07-18 | 迪帕微(上海)生物科技有限公司 | 一种硬组织切片防脱预处理装置及防脱预处理方法 |
| US20230392196A1 (en) * | 2022-06-06 | 2023-12-07 | Applied Materials, Inc. | RNA retrieval process for preparing formalin-fixed, paraffin-embedded (FFPE) tissue samples for in situ hybridization |
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| US2137549A (en) | 1935-05-10 | 1938-11-22 | Union Oil Co | Method for dewaxing oils |
| US3769934A (en) | 1973-01-26 | 1973-11-06 | Dow Chemical Co | Sample preparing apparatus |
| DE2753710C2 (de) * | 1977-12-02 | 1980-01-03 | Thomas, Carlos, Prof. Dr., 7808 Waldkirch | Verfahren zur Entwässerung von Gewebeproben o.dgl. und Vorrichtung zur Durchführung des Verfahrens |
| DE2915248C3 (de) | 1979-04-14 | 1982-01-14 | Gise, Frhr. von, Hardo, Dr.med., 7400 Tübingen | Einrichtung zum automatischen wahlweisen u. exakten Behandeln von Präparaten |
| US4379525A (en) | 1981-08-06 | 1983-04-12 | Owens-Illinois, Inc. | Process for recycling plastic container scrap |
| JPS60131442A (ja) * | 1983-12-21 | 1985-07-13 | Chiyoda Seisakusho:Kk | 包埋装置におけるパラフイン障害除去装置 |
| US5023187A (en) * | 1985-09-13 | 1991-06-11 | Fisher Scientific Company | Method and device for accelerated treatment of thin sample on surface |
| JP2693450B2 (ja) | 1987-09-16 | 1997-12-24 | 株式会社東芝 | 磁気ヘッド |
| JPH0725669Y2 (ja) * | 1989-06-26 | 1995-06-07 | 株式会社千代田製作所 | 一槽式標本処理装置に於ける気泡混入防止装置 |
| US5273905A (en) * | 1991-02-22 | 1993-12-28 | Amoco Corporation | Processing of slide mounted material |
| US5695942A (en) * | 1993-02-03 | 1997-12-09 | Histaggen Incorporated | Automated histo-cytochemistry apparatus and encapsulation system for processing biological materials |
| US5344637A (en) | 1993-06-01 | 1994-09-06 | Camiener Gerald W | Use of saturated, ring-containing compounds as clearing solvents in histologic procedures |
| US6632598B1 (en) | 1994-03-11 | 2003-10-14 | Biogenex Laboratories | Deparaffinization compositions and methods for their use |
| US6451551B1 (en) * | 1994-03-11 | 2002-09-17 | Biogenex Laboratories | Releasing embedding media from tissue specimens |
| EP0843169B1 (de) * | 1995-02-25 | 2003-03-19 | Roche Diagnostics GmbH | Vorrichtung zur Bearbeitung von Proben auf Objekträgern |
| JP2901521B2 (ja) * | 1995-07-31 | 1999-06-07 | アロカ株式会社 | 生物組織の処理装置 |
| JPH1019749A (ja) * | 1996-06-28 | 1998-01-23 | Aloka Co Ltd | 生物組織処理装置 |
| US5948359A (en) | 1997-03-21 | 1999-09-07 | Biogenex Laboratories | Automated staining apparatus |
| US8137619B2 (en) | 1997-08-11 | 2012-03-20 | Ventana Medical Systems, Inc. | Memory management method and apparatus for automated biological reaction system |
| US6855559B1 (en) * | 1998-09-03 | 2005-02-15 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
| AU763354B2 (en) | 1998-02-27 | 2003-07-17 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6183693B1 (en) * | 1998-02-27 | 2001-02-06 | Cytologix Corporation | Random access slide stainer with independent slide heating regulation |
| JP4082782B2 (ja) * | 1998-04-30 | 2008-04-30 | 雪印乳業株式会社 | 歯周病予防及び改善剤 |
| US7410753B2 (en) * | 1998-09-03 | 2008-08-12 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
| JP3782663B2 (ja) | 1998-09-03 | 2006-06-07 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 生物学的試料からの包埋媒体の除去および自動化された染色装置における細胞コンディショニング |
| US6544798B1 (en) | 1999-02-26 | 2003-04-08 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
| US6248535B1 (en) * | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| WO2001073399A2 (en) | 2000-03-24 | 2001-10-04 | Biogenex Laboratories, Inc. | Device and methods for automated specimen processing |
| JP4596501B2 (ja) * | 2000-04-10 | 2010-12-08 | サクラ精機株式会社 | 顕微鏡標本のカバーガラス貼着装置 |
| CN1161285C (zh) * | 2000-08-08 | 2004-08-11 | 杨传芳 | 溶氧法污水处理装置 |
| EP1325300A1 (en) | 2000-09-15 | 2003-07-09 | Biogenex Laboratories | ENHANCEMENT OF i IN SITU /i HYBRIDIZATION |
| US7468161B2 (en) * | 2002-04-15 | 2008-12-23 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
| ES2424988T3 (es) | 2002-04-15 | 2013-10-10 | Ventana Medical Systems, Inc. | Sistema automatizado de coloración de placas portaobjetos con elevada velocidad de producción |
| US7438940B2 (en) | 2002-04-19 | 2008-10-21 | E. I. Du Pont De Nemours And Company | Film and film structures having improved oxygen transmission, forming, and puncture resistances |
| WO2004057308A1 (en) | 2002-12-20 | 2004-07-08 | Dakocytomation Denmark A/S | An automated sample processing apparatus and a method of automated treating of samples and use of such apparatus |
| US7648678B2 (en) | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
| US7767152B2 (en) * | 2003-08-11 | 2010-08-03 | Sakura Finetek U.S.A., Inc. | Reagent container and slide reaction retaining tray, and method of operation |
| US20070248924A1 (en) | 2003-12-10 | 2007-10-25 | Torstein Ljungmann | Apparatus for treatment of tissue specimens |
| AU2005267018B2 (en) * | 2004-07-23 | 2008-10-23 | Ventana Medical Systems, Inc. | Method and apparatus for applying fluids to a biological sample |
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| DE102009025574A1 (de) * | 2009-06-19 | 2010-12-23 | Leica Biosystems Nussloch Gmbh | Verfahren zum automatischen Bearbeiten von Gewebeproben in einem Gewebeprozessor |
| DE202009018981U1 (de) * | 2009-07-01 | 2015-03-11 | Axagarius Gmbh & Co. Kg | Verwendung eines Kits für die Isolierung von Biomolekülen aus biologischen Proben sowie Kit dafür |
| CN101693156B (zh) * | 2009-10-23 | 2011-05-25 | 张子楠 | 发电厂凝汽器内多功能净化装置 |
| CN201607343U (zh) | 2009-12-17 | 2010-10-13 | 巨石集团有限公司 | 液体取样装置 |
| CN201605875U (zh) * | 2010-03-08 | 2010-10-13 | 河北和拓嘉实环境工程有限公司 | 防风抑尘网 |
-
2012
- 2012-02-28 CN CN201710343058.XA patent/CN107255584B/zh active Active
- 2012-02-28 CA CA2826056A patent/CA2826056C/en active Active
- 2012-02-28 AU AU2012222963A patent/AU2012222963B2/en active Active
- 2012-02-28 JP JP2013555948A patent/JP6013376B2/ja active Active
- 2012-02-28 EP EP12752162.3A patent/EP2686662B1/en active Active
- 2012-02-28 CN CN201280010677.2A patent/CN103930761B/zh active Active
- 2012-02-28 WO PCT/IB2012/000405 patent/WO2012117294A2/en not_active Ceased
- 2012-02-28 US US14/001,714 patent/US10295442B2/en active Active
-
2016
- 2016-08-30 AU AU2016222358A patent/AU2016222358A1/en not_active Abandoned
-
2018
- 2018-10-19 AU AU2018250513A patent/AU2018250513B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012117294A2 (en) | 2012-09-07 |
| EP2686662B1 (en) | 2022-01-19 |
| EP2686662A2 (en) | 2014-01-22 |
| US20140051118A1 (en) | 2014-02-20 |
| JP2014523514A (ja) | 2014-09-11 |
| WO2012117294A3 (en) | 2016-07-28 |
| AU2018250513A1 (en) | 2018-11-15 |
| CN107255584B (zh) | 2021-04-13 |
| CA2826056A1 (en) | 2012-09-07 |
| AU2018250513B2 (en) | 2020-05-21 |
| EP2686662A4 (en) | 2017-07-26 |
| CN103930761A (zh) | 2014-07-16 |
| CN107255584A (zh) | 2017-10-17 |
| AU2012222963B2 (en) | 2016-09-22 |
| AU2012222963A1 (en) | 2013-08-22 |
| AU2016222358A1 (en) | 2016-09-22 |
| CA2826056C (en) | 2021-01-26 |
| US10295442B2 (en) | 2019-05-21 |
| CN103930761B (zh) | 2017-06-13 |
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