JP6006293B2 - モノカチオン性ヒドロキシル官能性を有するエーテル類 - Google Patents
モノカチオン性ヒドロキシル官能性を有するエーテル類 Download PDFInfo
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- JP6006293B2 JP6006293B2 JP2014506574A JP2014506574A JP6006293B2 JP 6006293 B2 JP6006293 B2 JP 6006293B2 JP 2014506574 A JP2014506574 A JP 2014506574A JP 2014506574 A JP2014506574 A JP 2014506574A JP 6006293 B2 JP6006293 B2 JP 6006293B2
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- IEURNECCLGSRFH-UHFFFAOYSA-N CC[N+](CC)(CCOCCO)CC(CO)O Chemical compound CC[N+](CC)(CCOCCO)CC(CO)O IEURNECCLGSRFH-UHFFFAOYSA-N 0.000 description 1
- FYSWCIHHIUMNEW-UHFFFAOYSA-N CC[N+](CCO)(CCOCCO)CC(CO)O Chemical compound CC[N+](CCO)(CCOCCO)CC(CO)O FYSWCIHHIUMNEW-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
Description
2,3−ジヒドロキシ−N−(2−(2−ヒドロキシエトキシ)エチル)−N,N−ジメチルプロパン−1−アミニウムクロライドを生成させるための3−クロロ−1,2−プロパンジオールと、2−[2−(ジメチルアミノ)エトキシ]エタノールとの反応
N,N−ジエチル−2,3−ジヒドロキシ−N−(2−(2−ヒドロキシエトキシ)エチル)プロパン−1−アミニウムクロライドを生成するための3−クロロ−1,2−プロパンジオールと、2−[2−(ジエチルアミノ)エトキシ]エタノールとの反応
N−エチル−2,3−ジヒドロキシ−N−(2−(2−ヒドロキシエトキシ)エチル)−N−(2−ヒドロキシエチル)プロパン−1−アミニウムクロライドを生成するための3−クロロ−1,2−プロパンジオールと、エチル(2−ヒドロキシエチル)[2−(2−ヒドロキシエトキシ)エチル]アミンとの反応
2,3−ジヒドロキシ−N−(2−(2−ヒドロキシエトキシ)プロピル)−N,N−ジメチルプロパン−1−アミニウムクロライドを生成させるための3−クロロ−1,2−プロパンジオールと、2−[2−(ジメチルアミノ)−1−メチルエトキシ]エタノールとの反応
実質的に実施例1〜4に従って調製される化合物を製造し、さらに、他の従来成分を含有するパーソナルケア用組成物へと製剤化した。該組成物を、本発明の組成物と従来の組成物とを比較するように依頼した訓練されたパネリストによって評価した。
本開示は以下も包含する。
[1] 式(I)の塩を含む化合物。
[2] 式中のmが2、3又は4である、上記態様1に記載の化合物。
[3] 式中の少なくとも1つのR 4a が−CH 3 である、上記態様1に記載の化合物。
[4] 式中のR 4a が−CH 2 OHである、上記態様1に記載の化合物。
[5] 式中のR 4b が−CH 2 CH 3 である、上記態様1に記載の化合物。
[6] 式中のR 4a 及びR 4b が協働してシクロヘキシル基を形成する、上記態様1に記載の化合物。
[7] 式中のR 5 が−CH 2 CH 2 OHである、上記態様1に記載の化合物。
[8] 式中のR 1a 及びR 1b がそれぞれHである、上記態様1に記載の化合物。
[9] 式中のR 2a 及びR 2b がそれぞれHである、上記態様1に記載の化合物。
[10] 式中のR 3a 及びR 3b が同一である、上記態様1に記載の化合物。
[11] 式中のR 3a 及びR 3b がそれぞれ−CH 3 である、上記態様10に記載の化合物。
[12] 式中のR 3a 及びR 3b がそれぞれ−CH 2 CH 3 である、上記態様10に記載の化合物。
[13] 式中のR 3a 及びR 3b がそれぞれ−CH 2 CH 2 OHである、上記態様10に記載の化合物。
[14] 式中のR 3a 及びR 3b が同一でない、上記態様1に記載の化合物。
[15] 式中のR 3a が−CH 2 CH 2 OHである、上記態様14に記載の化合物。
[16] 式中のR 3b が−(CH 2 ) 3 CH 3 である、上記態様15に記載の化合物。
[17] パーソナルケア用組成物に保湿性を付与する方法であって、前記パーソナルケア用組成物中に上記態様1に記載の化合物を含有させる工程を含む、方法。
[18] 上記態様1に記載の化合物を含むヘアケア用組成物。
[19] 上記態様1に記載の化合物を含むスキンケア用組成物。
Claims (5)
- 式(I)の塩を含む化合物。
- 式中のR3a及びR3bがそれぞれ−CH3、それぞれ−CH2CH3若しくはそれぞれ−CH2CH2OHであり、又はR3aが−CH2CH2OH及びR3bが−(CH2)3CH3である、請求項1に記載の化合物。
- パーソナルケア用組成物に保湿性を付与する方法であって、前記パーソナルケア用組成物中に請求項1に記載の化合物を含有させる工程を含む、方法。
- 請求項1に記載の化合物を含むヘアケア用組成物。
- 請求項1に記載の化合物を含むスキンケア用組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161477851P | 2011-04-21 | 2011-04-21 | |
US61/477,851 | 2011-04-21 | ||
PCT/US2012/034441 WO2012145621A1 (en) | 2011-04-21 | 2012-04-20 | Ethers with monocationic polyhydroxyl functionality |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014523402A JP2014523402A (ja) | 2014-09-11 |
JP6006293B2 true JP6006293B2 (ja) | 2016-10-12 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014506574A Active JP6006293B2 (ja) | 2011-04-21 | 2012-04-20 | モノカチオン性ヒドロキシル官能性を有するエーテル類 |
Country Status (6)
Country | Link |
---|---|
US (1) | US9220670B2 (ja) |
EP (1) | EP2678308B1 (ja) |
JP (1) | JP6006293B2 (ja) |
CN (1) | CN103562176B (ja) |
BR (1) | BR112013026601B1 (ja) |
WO (1) | WO2012145621A1 (ja) |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL136722B1 (en) * | 1981-08-13 | 1986-03-31 | Inst Chemii Przemyslowej | Method of obtaining novel 3-/n,n,n-quaternary ammonia derivatives/ of 2-hydroxypropano-1-hydroxyalkanodicarboxylates |
US6177577B1 (en) | 1991-11-15 | 2001-01-23 | The Dow Chemical Company | Dicationic and polycationic monoprimary alcohols and derivatives thereof |
DE4238213A1 (de) | 1992-11-12 | 1994-05-19 | Henkel Kgaa | Quaternierte Bis-sorbitylalkylamine |
NZ331813A (en) | 1996-03-11 | 2001-03-30 | G | Benzothiepine compounds having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
US7214806B2 (en) | 2004-03-05 | 2007-05-08 | Sachem, Inc. | Synthetic multiple quaternary ammonium salts |
US6869977B1 (en) | 2004-04-09 | 2005-03-22 | Colonial Chemical Inc. | Skin moisturization compound |
US7176172B2 (en) | 2004-10-25 | 2007-02-13 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Quaternary ammonium polyol salts as anti-aging actives in personal care compositions |
US7282471B2 (en) | 2005-09-08 | 2007-10-16 | Conopco, Inc. | Personal care compositions with glycerin and hydroxypropyl quaternary ammonium salts |
RU2376977C1 (ru) | 2005-08-25 | 2009-12-27 | Колгейт-Палмолив Компани | Увлажняющие композиции |
CN101370770B (zh) | 2006-02-15 | 2013-09-18 | 陶氏环球技术有限责任公司 | 二羟基三烷基卤化铵的制备方法 |
US7659234B2 (en) | 2006-03-07 | 2010-02-09 | Conopco, Inc. | Personal care compositions containing quaternary ammonium trihydroxy substituted dipropyl ether |
US8206754B2 (en) | 2007-05-30 | 2012-06-26 | Conopco, Inc. | Personal care composition with cocoa butter and dihydroxypropyl ammonium salts |
US8003404B2 (en) | 2007-11-28 | 2011-08-23 | University Of Massachusetts | Methods and compositions for pathogen detection using nanoparticle-fluorescent polymer complexes |
CN103140469B (zh) * | 2010-09-30 | 2016-03-02 | 陶氏环球技术有限责任公司 | 季铵多羟基化合物及其在个人护理组合物中的用途 |
-
2012
- 2012-04-20 BR BR112013026601-5A patent/BR112013026601B1/pt active IP Right Grant
- 2012-04-20 US US14/006,746 patent/US9220670B2/en active Active
- 2012-04-20 JP JP2014506574A patent/JP6006293B2/ja active Active
- 2012-04-20 CN CN201280019397.8A patent/CN103562176B/zh active Active
- 2012-04-20 EP EP12718534.6A patent/EP2678308B1/en active Active
- 2012-04-20 WO PCT/US2012/034441 patent/WO2012145621A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
JP2014523402A (ja) | 2014-09-11 |
BR112013026601B1 (pt) | 2018-02-06 |
US20140030208A1 (en) | 2014-01-30 |
BR112013026601A2 (pt) | 2017-05-02 |
EP2678308B1 (en) | 2016-10-26 |
EP2678308A1 (en) | 2014-01-01 |
CN103562176B (zh) | 2016-05-18 |
US9220670B2 (en) | 2015-12-29 |
WO2012145621A1 (en) | 2012-10-26 |
CN103562176A (zh) | 2014-02-05 |
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